ASYMPTOTIC DISTRIBUTIONS OF SEMIPARAMETRIC MAXIMUM LIKELIHOOD ESTIMATORS WITH ESTIMATING EQUATIONS FOR GROUP-CENSORED DATA

Semiparametric maximum likelihood estimation with estimating equations (SMLE) is more flexible than traditional methods; it has fewer restrictions on distributions and regression models. The required information about distribution and regression structures is incorporated in estimating equations of the SMLE to improve the estimation quality of non‐parametric methods. The likelihood of SMLE for censored data involves complicated implicit functions without closed‐form expressions, and the first derivatives of the log‐profile‐likelihood cannot be expressed as summations of independent and identically distributed random variables; it is challenging to derive asymptotic properties of the SMLE for censored data. For group‐censored data, the paper shows that all the implicit functions are well defined and obtains the asymptotic distributions of the SMLE for model parameters and lifetime distributions. With several examples the paper compares the SMLE, the regular non‐parametric likelihood estimation method and the parametric MLEs in terms of their asymptotic efficiencies, and illustrates application of SMLE. Various asymptotic distributions of the likelihood ratio statistics are derived for testing the adequacy of estimating equations and a partial set of parameters equal to some known values.     

Analysis of Type-II hybrid censored competing risks data

Kundu and Gupta [Analysis of hybrid life-tests in presence of competing risks. Metrica. 2007;65:159–170] provided the analysis of Type-I hybrid censored competing risks data, when the lifetime distributions of the competing cause of failures follows exponential distribution. In this paper, we consider the analysis of Type-II hybrid censored competing risks data. It is assumed that latent lifetime distributions of the competing causes of failures follow independent exponential distributions with different scale parameters. It is observed that the maximum likelihood estimators of the unknown parameters do not always exist. We propose the modified estimators of the scale parameters, which coincide with the corresponding maximum likelihood estimators when they exist, and asymptotically they are equivalent. We obtain the exact distribution of the proposed estimators. Using the exact distributions of the proposed estimators, associated confidence intervals are obtained. The asymptotic and bootstrap confidence intervals of the unknown parameters are also provided. Further, Bayesian inference of some unknown parametric functions under a very flexible Beta-Gamma prior is considered. Bayes estimators and associated credible intervals of the unknown parameters are obtained using the Monte Carlo method. Extensive Monte Carlo simulations are performed to see the effectiveness of the proposed estimators and one real data set has been analysed for the illustrative purposes. It is observed that the proposed model and the method work quite well for this data set.     

Quasi-likelihood from<Emphasis Type="Italic">M</Emphasis>-estimators: A numerical comparison with empirical likelihood

In this paper we compare two robust pseudo-likelihoods for a parameter of interest, also in the presence of nuisance parameters. These functions are obtained by computing quasi-likelihood and empirical likelihood from the estimating equations which define robustM-estimators. Application examples in the context of linear transformation models are considered. Monte Carlo studies are performed in order to assess the finite-sample performance of the inferential procedures based on quasi-and empirical likelihood, when the objective is the construction of robust confidence regions.     

A Study of Interval Censoring in Parametric Regression Models

Parametric models for interval censored data can now easily be fitted with minimal programming in certain standard statistical software packages. Regression equations can be introduced, both for the location and for the dispersion parameters. Finite mixture models can also be fitted, with a point mass on right (or left) censored observations, to allow for individuals who cannot have the event (or already have it). This mixing probability can also be allowed to follow a regression equation.Here, models based on nine different distributions are compared for three examples of heavily censored data as well as a set of simulated data. We find that, for parametric models, interval censoring can often be ignored and that the density, at centres of intervals, can be used instead in the likelihood function, although the approximation is not always reliable. In the context of heavily interval censored data, the conclusions from parametric models are remarkably robust with changing distributional assumptions and generally more informative than the corresponding non-parametric models.     

Estimation in Maxwell distribution with randomly censored data

In many practical situations, complete data are not available in lifetime studies. Many of the available observations are right censored giving survival information up to a noted time and not the exact failure times. This constitutes randomly censored data. In this paper, we consider Maxwell distribution as a survival time model. The censoring time is also assumed to follow a Maxwell distribution with a different parameter. Maximum likelihood estimators and confidence intervals for the parameters are derived with randomly censored data. Bayes estimators are also developed with inverted gamma priors and generalized entropy loss function. A Monte Carlo simulation study is performed to compare the developed estimation procedures. A real data example is given at the end of the study.     

A complementary generalized linear failure rate-geometric distribution

In this article, we shall attempt to introduce a new class of lifetime distributions, which enfolds several known distributions such as the generalized linear failure rate distribution and covers both positive as well as negative skewed data. This new four-parameter distribution allows for flexible hazard rate behavior. Indeed, the hazard rate function here can be increasing, decreasing, bathtub-shaped, or upside-down bathtub-shaped. We shall first study some basic distributional properties of the new model such as the cumulative distribution function, the density of the order statistics, their moments, and Rényi entropy. Estimation of the stress-strength parameter as an important reliability property is also studied. The maximum likelihood estimation procedure for complete and censored data and Bayesian method are used for estimating the parameters involved. Finally, application of the new model to three real datasets is illustrated to show the flexibility and potential of the new model compared to rival models.     

Comparisons of methods of estimation for a pareto distribution of the first kind

This paper compares methods of estimation for the parameters of a Pareto distribution of the first kind to determine which method provides the better estimates when the observations are censored, The unweighted least squares (LS) and the maximum likelihood estimates (MLE) are presented for both censored and uncensored data. The MLE's are obtained using two methods, In the first, called the ML method, it is shown that log-likelihood is maximized when the scale parameter is the minimum sample value. In the second method, called the modified ML (MML) method, the estimates are found by utilizing the maximum likelihood value of the shape parameter in terms of the scale parameter and the equation for the mean of the first order statistic as a function of both parameters. Since censored data often occur in applications, we study two types of censoring for their effects on the methods of estimation: Type II censoring and multiple random censoring. In this study we consider different sample sizes and several values of the true shape and scale parameters.

Comparisons are made in terms of bias and the mean squared error of the estimates. We propose that the LS method be generally preferred over the ML and MML methods for estimating the Pareto parameter γ for all sample sizes, all values of the parameter and for both complete and censored samples. In many cases, however, the ML estimates are comparable in their efficiency, so that either estimator can effectively be used. For estimating the parameter α, the LS method is also generally preferred for smaller values of the parameter (α ≤4). For the larger values of the parameter, and for censored samples, the MML method appears superior to the other methods with a slight advantage over the LS method. For larger values of the parameter α, for censored samples and all methods, underestimation can be a problem.     

Reliability estimation in generalized inverted exponential distribution with progressively type II censored sample

In this paper, a generalization of inverted exponential distribution is considered as a lifetime model [A.M. Abouammoh and A.M. Alshingiti, Reliability estimation of generalized inverted exponential distribution, J. Statist. Comput. Simul. 79(11) (2009), pp. 1301–1315]. Its reliability characteristics and important distributional properties are discussed. Maximum likelihood estimation of the two parameters involved along with reliability and failure rate functions are derived. The method of least square estimation of parameters is also studied here. In view of cost and time constraints, type II progressively right censored sampling scheme has been used. For illustration of the performance of the estimates, a Monte Carlo simulation study is carried out. Finally, a real data example is given to show the practical applications of the paper.     

Inference from PseudoLikelihoods with Plug‐In Estimates

Effective implementation of likelihood inference in models for high‐dimensional data often requires a simplified treatment of nuisance parameters, with these having to be replaced by handy estimates. In addition, the likelihood function may have been simplified by means of a partial specification of the model, as is the case when composite likelihood is used. In such circumstances tests and confidence regions for the parameter of interest may be constructed using Wald type and score type statistics, defined so as to account for nuisance parameter estimation or partial specification of the likelihood. In this paper a general analytical expression for the required asymptotic covariance matrices is derived, and suggestions for obtaining Monte Carlo approximations are presented. The same matrices are involved in a rescaling adjustment of the log likelihood ratio type statistic that we propose. This adjustment restores the usual chi‐squared asymptotic distribution, which is generally invalid after the simplifications considered. The practical implication is that, for a wide variety of likelihoods and nuisance parameter estimates, confidence regions for the parameters of interest are readily computable from the rescaled log likelihood ratio type statistic as well as from the Wald type and score type statistics. Two examples, a measurement error model with full likelihood and a spatial correlation model with pairwise likelihood, illustrate and compare the procedures. Wald type and score type statistics may give rise to confidence regions with unsatisfactory shape in small and moderate samples. In addition to having satisfactory shape, regions based on the rescaled log likelihood ratio type statistic show empirical coverage in reasonable agreement with nominal confidence levels.     

A note on interval‐censored lifetime data and the constant‐sum condition of oiler,gómez & calle (2004)

Oiler, Gomez & Calle (2004) give a constant sum condition for processes that generate interval‐censored lifetime data. They show that in models satisfying this condition, it is possible to estimate non‐parametrically the lifetime distribution based on a well‐known simplified likelihood. The author shows that this constant‐sum condition is equivalent to the existence of an observation process that is independent of lifetimes and which gives the same probability distribution for the observed data as the underlying true process.     

Analysis of hybrid censored competing risks data

In this paper, we consider the analysis of hybrid censored competing risks data, based on Cox's latent failure time model assumptions. It is assumed that lifetime distributions of latent causes of failure follow Weibull distribution with the same shape parameter, but different scale parameters. Maximum likelihood estimators (MLEs) of the unknown parameters can be obtained by solving a one-dimensional optimization problem, and we propose a fixed-point type algorithm to solve this optimization problem. Approximate MLEs have been proposed based on Taylor series expansion, and they have explicit expressions. Bayesian inference of the unknown parameters are obtained based on the assumption that the shape parameter has a log-concave prior density function, and for the given shape parameter, the scale parameters have Beta–Gamma priors. We propose to use Markov Chain Monte Carlo samples to compute Bayes estimates and also to construct highest posterior density credible intervals. Monte Carlo simulations are performed to investigate the performances of the different estimators, and two data sets have been analysed for illustrative purposes.     

The Kumaraswamy modified Weibull distribution: theory and applications

A five-parameter extension of the Weibull distribution capable of modelling a bathtub-shaped hazard rate function is introduced and studied. The beauty and importance of the new distribution lies in its ability to model both monotone and non-monotone failure rates that are quite common in lifetime problems and reliability. The proposed distribution has a number of well-known lifetime distributions as special sub-models, such as the Weibull, extreme value, exponentiated Weibull, generalized Rayleigh and modified Weibull (MW) distributions, among others. We obtain quantile and generating functions, mean deviations, Bonferroni and Lorenz curves and reliability. We provide explicit expressions for the density function of the order statistics and their moments. For the first time, we define the log-Kumaraswamy MW regression model to analyse censored data. The method of maximum likelihood is used for estimating the model parameters and the observed information matrix is determined. Two applications illustrate the potentiality of the proposed distribution.     

The log-exponentiated generalized gamma regression model for censored data

For the first time, we introduce a generalized form of the exponentiated generalized gamma distribution [Cordeiro et al. The exponentiated generalized gamma distribution with application to lifetime data, J. Statist. Comput. Simul. 81 (2011), pp. 827–842.] that is the baseline for the log-exponentiated generalized gamma regression model. The new distribution can accommodate increasing, decreasing, bathtub- and unimodal-shaped hazard functions. A second advantage is that it includes classical distributions reported in the lifetime literature as special cases. We obtain explicit expressions for the moments of the baseline distribution of the new regression model. The proposed model can be applied to censored data since it includes as sub-models several widely known regression models. It therefore can be used more effectively in the analysis of survival data. We obtain maximum likelihood estimates for the model parameters by considering censored data. We show that our extended regression model is very useful by means of two applications to real data.     

Gompertz-power series distributions

ABSTRACT

In this article, we introduce the Gompertz power series (GPS) class of distributions which is obtained by compounding Gompertz and power series distributions. This distribution contains several lifetime models such as Gompertz-geometric (GG), Gompertz-Poisson (GP), Gompertz-binomial (GB), and Gompertz-logarithmic (GL) distributions as special cases. Sub-models of the GPS distribution are studied in details. The hazard rate function of the GPS distribution can be increasing, decreasing, and bathtub-shaped. We obtain several properties of the GPS distribution such as its probability density function, and failure rate function, Shannon entropy, mean residual life function, quantiles, and moments. The maximum likelihood estimation procedure via a EM-algorithm is presented, and simulation studies are performed for evaluation of this estimation for complete data, and the MLE of parameters for censored data. At the end, a real example is given.     

Using BBPSO Algorithm to Estimate the Weibull Parameters with Censored Data

This article proposes the maximum likelihood estimates based on bare bones particle swarm optimization (BBPSO) algorithm for estimating the parameters of Weibull distribution with censored data, which is widely used in lifetime data analysis. This approach can produce more accuracy of the parameter estimation for the Weibull distribution. Additionally, the confidence intervals for the estimators are obtained. The simulation results show that the BB PSO algorithm outperforms the Newton–Raphson method in most cases in terms of bias, root mean square of errors, and coverage rate. Two examples are used to demonstrate the performance of the proposed approach. The results show that the maximum likelihood estimates via BBPSO algorithm perform well for estimating the Weibull parameters with censored data.     

A log-location-scale lifetime distribution with censored data: Regression modeling,residuals, and global influence

In survival analysis applications, the presence of failure rate functions with non monotone shapes is common. Therefore, models that can accommodate such different shapes are needed. In this article, we present a location regression model based on the complementary exponentiated exponential geometric distribution as an alternative to the usual bathtub, increasing, and decreasing failure rates in lifetime data. Assuming censored data, we consider the maximum likelihood inference for analysis, graphical verification for residuals, and test statistics for influential points.     

Robust regression for estimating the Burr XII parameters with outliers

The Burr XII distribution offers a more flexible alternative to the lognormal, log-logistic and Weibull distributions. Outliers can occur during reliability life testing. Thus, we need an efficient method to estimate the parameters of the Burr XII distribution for censored data with outliers. The objective of this paper is to present a robust regression (RR) method called M-estimator to estimate the parameters of a two-parameter Burr XII distribution based on the probability plotting procedure for both the complete and multiply-censored data with outliers. The simulation results show that the RR method outperforms the unweighted least squares and maximum likelihood methods in most cases in terms of bias and errors in the root mean square.     

The Weibull Marshall–Olkin family: Regression model and application to censored data

We introduce a new class of distributions called the Weibull Marshall–Olkin-G family. We obtain some of its mathematical properties. The special models of this family provide bathtub-shaped, decreasing-increasing, increasing-decreasing-increasing, decreasing-increasing-decreasing, monotone, unimodal and bimodal hazard functions. The maximum likelihood method is adopted for estimating the model parameters. We assess the performance of the maximum likelihood estimators by means of two simulation studies. We also propose a new family of linear regression models for censored and uncensored data. The flexibility and importance of the proposed models are illustrated by means of three real data sets.     

Fitting linear regression models to censored data by least squares and maximum likelihood methods

Several approaches have been suggested for fitting linear regression models to censored data. These include Cox's propor­tional hazard models based on quasi-likelihoods. Methods of fitting based on least squares and maximum likelihoods have also been proposed. The methods proposed so far all require special purpose optimization routines. We describe an approach here which requires only a modified standard least squares routine.

We present methods for fitting a linear regression model to censored data by least squares and method of maximum likelihood. In the least squares method, the censored values are replaced by their expectations, and the residual sum of squares is minimized. Several variants are suggested in the ways in which the expect­ation is calculated. A parametric (assuming a normal error model) and two non-parametric approaches are described. We also present a method for solving the maximum likelihood equations in the estimation of the regression parameters in the censored regression situation. It is shown that the solutions can be obtained by a recursive algorithm which needs only a least squares routine for optimization. The suggested procesures gain considerably in computational officiency. The Stanford Heart Transplant data is used to illustrate the various methods.     

Non Null Asymptotic Distributions of Some Criteria in Censored Exponential Regression

In this article, we consider the class of censored exponential regression models which is very useful for modeling lifetime data. Under a sequence of Pitman alternatives, the asymptotic expansions up to order n^{? 1/2} of the non null distribution functions of the likelihood ratio, Wald, Rao score, and gradient statistics are derive in this class of models. The non null asymptotic distribution functions of these statistics are obtained for testing a composite null hypothesis in the presence of nuisance parameters. The power of all four tests, which are equivalent to first order, are compared based on these non null asymptotic expansions. Furthermore, in order to compare the finite-sample performance of these tests in this class of models, we consider Monte Carlo simulations. We also present an empirical application for illustrative purposes.