An objective Bayesian estimation in a two-period crossover design

Two-period crossover design is one of the commonly used designs in clinical trials. But, the estimation of treatment effect is complicated by the possible presence of carryover effect. It is known that ignoring the carryover effect when it exists can lead to poor estimates of the treatment effect. The classical approach by Grizzle (1965 Grizzle, J.E. (1965). The two-period change-over design and its use in clinical trials. Biometrics 21:467–480. See Grizzle (1974) for corrections.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) consists of two stages. First, a preliminary test is conducted on carryover effect. If the carryover effect is significant, analysis is based only on data from period one; otherwise, analysis is based on data from both periods. A Bayesian approach with improper priors was proposed by Grieve (1985 Grieve, A.P. (1985). A Bayesian analysis of the two-period crossover design for clinical trials. Biometrics 41:979–990.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) which uses a mixture of two models: a model with carryover effect and another without. The indeterminacy of the Bayes factor due to the arbitrary constant in the improper prior was addressed by assigning a minimally discriminatory value to the constant. In this article, we present an objective Bayesian estimation approach to the two-period crossover design which is also based on a mixture model, but using the commonly recommended Zellner–Siow g-prior. We provide simulation studies and a real data example and compare the numerical results with Grizzle (1965 Grizzle, J.E. (1965). The two-period change-over design and its use in clinical trials. Biometrics 21:467–480. See Grizzle (1974) for corrections.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar])’s and Grieve (1985 Grieve, A.P. (1985). A Bayesian analysis of the two-period crossover design for clinical trials. Biometrics 41:979–990.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar])’s approaches.     

Buffered Autoregressive Models With Conditional Heteroscedasticity: An Application to Exchange Rates

This article introduces a new model called the buffered autoregressive model with generalized autoregressive conditional heteroscedasticity (BAR-GARCH). The proposed model, as an extension of the BAR model in Li et al. (2015 Li, G.D., Guan, B., Li, W.K., and Yu, P. L.H. (2015), “Hysteretic Autoregressive Time Series Models,” Biometrika, 102, 717–723.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]), can capture the buffering phenomena of time series in both the conditional mean and variance. Thus, it provides us a new way to study the nonlinearity of time series. Compared with the existing AR-GARCH and threshold AR-GARCH models, an application to several exchange rates highlights the importance of the BAR-GARCH model.     

Nonparametric test for stratum effects in the cox model with interval-censored data

The testing of the stratum effects in the Cox model is an important and commonly asked question in medical research as well as in many other fields. In this paper, we will discuss the problem where one observes interval-censored failure time data and generalize the procedure given in Sun and Yang (2000 Sun, J., and I. Yang. 2000. Nonparametric test for stratum effects in the cox model. Lifetime Data Analysis 6:321–30.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) for right-censored data. The asymptotic distribution of the new test statistic is established and the simulation study conducted for the evaluation of the finite sample properties of the method suggests that the generalized procedure seems to work well for practical situations. An application is provided.     

Linear transformation models for survival analysis with tumor growth information in cancer screening study

The complication in analyzing tumor data is that the tumors detected in a screening program tend to be slowly progressive tumors, which is the so-called left-truncated sampling that is inherent in screening studies. Under the assumption that all subjects have the same tumor growth function, Ghosh (2008 Ghosh, D. (2008). Proportional hazards regression for cancer studies. Biometrics 64:141–148.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) developed estimation procedures for the Cox proportional hazards model. Shen (2011a Shen, P.-S. (2011a). Proportional hazards regression for cancer screening data. J. Stat. Comput. Simul. 18:367–377.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) demonstrated that Ghosh (2008 Ghosh, D. (2008). Proportional hazards regression for cancer studies. Biometrics 64:141–148.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar])'s approach can be extended to the case when each subject has a specific growth function. In this article, under linear transformation model, we present a general framework to the analysis of data from cancer screening studies. We developed estimation procedures under linear transformation model, which includes Cox's model as a special case. A simulation study is conducted to demonstrate the potential usefulness of the proposed estimators.     

On weighted cumulative residual entropy

In analogy with the weighted Shannon entropy proposed by Belis and Guiasu (1968 Belis, M., Guiasu, S. (1968). A quantitative-qualitative measure of information in cybernetic systems. IEEE Trans. Inf. Th. IT-4:593–594.[Crossref], [Web of Science ®] , [Google Scholar]) and Guiasu (1986 Guiasu, S. (1986). Grouping data by using the weighted entropy. J. Stat. Plann. Inference 15:63–69.[Crossref], [Web of Science ®] , [Google Scholar]), we introduce a new information measure called weighted cumulative residual entropy (WCRE). This is based on the cumulative residual entropy (CRE), which is introduced by Rao et al. (2004 Rao, M., Chen, Y., Vemuri, B.C., Wang, F. (2004). Cumulative residual entropy: a new measure of information. IEEE Trans. Info. Theory 50(6):1220–1228.[Crossref], [Web of Science ®] , [Google Scholar]). This new information measure is “length-biased” shift dependent that assigns larger weights to larger values of random variable. The properties of WCRE and a formula relating WCRE and weighted Shannon entropy are given. Related studies of reliability theory is covered. Our results include inequalities and various bounds to the WCRE. Conditional WCRE and some of its properties are discussed. The empirical WCRE is proposed to estimate this new information measure. Finally, strong consistency and central limit theorem are provided.     

On generalized exponential chain ratio estimators under stratified two-phase random sampling

Sanaullah et al. (2014 Sanaullah, A., Ali, H.M., Noor ul Amin, M., Hanif, M. (2014). Generalized exponential chain ratio estimators under stratified two-phase random sampling. Appl. Math. Comput. 226:541–547.[Crossref], [Web of Science ®] , [Google Scholar]) have suggested generalized exponential chain ratio estimators under stratified two-phase sampling scheme for estimating the finite population mean. However, the bias and mean square error (MSE) expressions presented in that work need some corrections, and consequently the study based on efficiency comparison also requires corrections. In this article, we revisit Sanaullah et al. (2014 Sanaullah, A., Ali, H.M., Noor ul Amin, M., Hanif, M. (2014). Generalized exponential chain ratio estimators under stratified two-phase random sampling. Appl. Math. Comput. 226:541–547.[Crossref], [Web of Science ®] , [Google Scholar]) estimator and provide the correct bias and MSE expressions of their estimator. We also propose an estimator which is more efficient than several competing estimators including the classes of estimators in Sanaullah et al. (2014 Sanaullah, A., Ali, H.M., Noor ul Amin, M., Hanif, M. (2014). Generalized exponential chain ratio estimators under stratified two-phase random sampling. Appl. Math. Comput. 226:541–547.[Crossref], [Web of Science ®] , [Google Scholar]). Three real datasets are used for efficiency comparisons.     

A new efficient unrelated randomized response model

The present paper suggests an interesting and useful ramification of the unrelated randomized response model due to Pal and Singh (2012 Pal, S., and S. Singh. 2012. A new unrelated question randomized response model. Statistics 46 (1):99–109.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) [A new unrelated question randomized response model. Statistics 46 (1), 99–109] that can be used for any sampling scheme. We have shown theoretically and numerically that the proposed model is more efficient than Pal and Singh (2012 Pal, S., and S. Singh. 2012. A new unrelated question randomized response model. Statistics 46 (1):99–109.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) model.     

On extreme order statistics from heterogeneous beta distributions with applications

This paper treats the problem of stochastic comparisons for the extreme order statistics arising from heterogeneous beta distributions. Some sufficient conditions involved in majorization-type partial orders are provided for comparing the extreme order statistics in the sense of various magnitude orderings including the likelihood ratio order, the reversed hazard rate order, the usual stochastic order, and the usual multivariate stochastic order. The results established here strengthen and extend those including Kochar and Xu (2007 Kochar, S.C., Xu, M. (2007). Stochastic comparisons of parallel systems when components have proportional hazard rates. Probab. Eng. Inf. Sci. 21:597–609.[Crossref], [Web of Science ®] , [Google Scholar]), Mao and Hu (2010 Mao, T., Hu, T. (2010). Equivalent characterizations on orderings of order statistics and sample ranges. Probab. Eng. Inf. Sci. 24:245–262.[Crossref], [Web of Science ®] , [Google Scholar]), Balakrishnan et al. (2014 Balakrishnan, N., Barmalzan, G., Haidari, A. (2014). On usual multivariate stochastic ordering of order statistics from heterogeneous beta variables. J. Multivariate Anal. 127:147–150.[Crossref], [Web of Science ®] , [Google Scholar]), and Torrado (2015 Torrado, N. (2015). On magnitude orderings between smallest order statistics from heterogeneous beta distributions. J. Math. Anal. Appl. 426:824–838.[Crossref], [Web of Science ®] , [Google Scholar]). A real application in system assembly and some numerical examples are also presented to illustrate the theoretical results.     

Characterization results based on dynamic Tsallis cumulative residual entropy

In this article, the concept of cumulative residual entropy (CRE) given by Rao et al. (2004 Rao, M., Chen, Y., Vemuri, B.C., Wang, F. (2004). Cumulative residual entropy: A new measure of information. IEEE Trans. Inf. Theory 50:1220–1228.[Crossref], [Web of Science ®] , [Google Scholar]) is extended to Tsallis entropy function and dynamic version, both residual and past of it. We study some properties and characterization results for these generalized measures. In addition, we provide some characterization results of the first-order statistic based on the Tsallis survival entropy.     

Optimal allocations of coverage limits for two independent random losses of insurance policy

This article recasts the optimal allocations of coverage limits for two independent random losses. Under some regularity conditions on the two concerned probability density functions, we build the sufficient and necessary condition for the existence of the optimal allocation of coverage limits, and derive the optimal allocation whenever they do exist. The results supplement Lu and Meng (2011 Lu, Z.Y., Meng, L.L. (2011). Stochastic comparisons for allocations of upper limits and deductibles with applications. Insur.: Math. Econ. 48:338–343.[Crossref], [Web of Science ®] , [Google Scholar], Proposition 5.2) and Hu and Wang (2014 Hu, S., Wang, R. (2014). Stochastic comparisons and optimal allocation for policy limits and deductibles. Commun. Stat. – Theory Methods 43:151–164.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar], Theorem 5.1).     

On dynamic weighted survival entropy of order α

Recently, Abbasnejad et al. (2010 Abbasnejad, M., Arghami, N.R., Morgenthaler, S., Mohtashami Borzadaran, G.R. (2010). On the dynamic survival entropy. Stat. Probab. Lett. 80:1962–1971.[Crossref], [Web of Science ®] , [Google Scholar]) proposed a measure of uncertainty based on survival function, called the survival entropy of order α. A dynamic form of the survival entropy of order α is also proposed by them. In this paper, we derive the weighted form of these measures. The properties of the new measures are also discussed.     

Sample size estimation for comparing rates of change in K-group repeated count outcomes

Sample size estimation for comparing the rates of change in two-arm repeated measurements has been investigated by many investigators. In contrast, the literature has paid relatively less attention to sample size estimation for studies with multi-arm repeated measurements where the design and data analysis can be more complex than two-arm trials. For continuous outcomes, Jung and Ahn (2004 Jung, S., Ahn, C. (2004). K-sample test and sample size calculation for comparing slopes in data with repeated measurements. Biometrical J. 46(5):554–564.[Crossref], [Web of Science ®] , [Google Scholar]) and Zhang and Ahn (2013 Zhang, S., Ahn, C. (2013). Sample size calculation for comparing time-averaged responses in k-group repeated measurement studies. Comput. Stat. Data Anal. 58:283–291.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) have presented sample size formulas to compare the rates of change and time-averaged responses in multi-arm trials, using the generalized estimating equation (GEE) approach. To our knowledge, there has been no corresponding development for multi-arm trials with count outcomes. We present a sample size formula for comparing the rates of change in multi-arm repeated count outcomes using the GEE approach that accommodates various correlation structures, missing data patterns, and unbalanced designs. We conduct simulation studies to assess the performance of the proposed sample size formula under a wide range of designing configurations. Simulation results suggest that empirical type I error and power are maintained close to their nominal levels. The proposed method is illustrated using an epileptic clinical trial example.     

Successive comparisons between ordered normal means using isotonic regression estimators

In this study we discuss multiple comparison procedures for checking differences among a sequence of normal means with ordered restriction. Lee and Spurrier (1995 Lee, R.E., Spurrier, J.D. (1995). Successive comparisons between ordered treatments. J. Stat. Plann. Inference 43:323–330.[Crossref], [Web of Science ®] , [Google Scholar]) proposed a multiple comparison procedure which tests the difference between two adjacent means using the difference of sample means. In this study we propose a multiple comparison procedure modifying Lee and Spurrier's (1995 Lee, R.E., Spurrier, J.D. (1995). Successive comparisons between ordered treatments. J. Stat. Plann. Inference 43:323–330.[Crossref], [Web of Science ®] , [Google Scholar]) procedure using isotonic regression estimators instead of sample means. We determine the critical value for pairwise comparisons for a specified significance level. Furthermore, we formulate the power of the test. Finally, we give some numerical examples regarding critical values and power of the test intended to compare our procedure with Lee and Spurrier's (1995 Lee, R.E., Spurrier, J.D. (1995). Successive comparisons between ordered treatments. J. Stat. Plann. Inference 43:323–330.[Crossref], [Web of Science ®] , [Google Scholar]) procedure.     

A Bayesian control chart for a common coefficient of variation

By using the medical data analyzed by Kang et al. (2007 Kang, C.W., Lee, M.S., Seong, Y.J., Hawkins, D.M. (2007). A control chart for the coefficient of variation. J. Qual. Technol. 39(2):151–158.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]), a Bayesian procedure is applied to obtain control limits for the coefficient of variation. Reference and probability matching priors are derived for a common coefficient of variation across the range of sample values. By simulating the posterior predictive density function of a future coefficient of variation, it is shown that the control limits are effectively identical to those obtained by Kang et al. (2007 Kang, C.W., Lee, M.S., Seong, Y.J., Hawkins, D.M. (2007). A control chart for the coefficient of variation. J. Qual. Technol. 39(2):151–158.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) for the specific dataset they used. This article illustrates the flexibility and unique features of the Bayesian simulation method for obtaining posterior distributions, predictive intervals, and run-lengths in the case of the coefficient of variation. A simulation study shows that the 95% Bayesian confidence intervals for the coefficient of variation have the correct frequentist coverage.     

An efficient use of moment's ratios of scrambling variables in a randomized response technique

This paper aimed at providing an efficient new unbiased estimator for estimating the proportion of a potentially sensitive attribute in survey sampling. The suggested randomization device makes use of the means, variances of scrambling variables, and the two scalars lie between “zero” and “one.” Thus, the same amount of information has been used at the estimation stage. The variance formula of the suggested estimator has been obtained. We have compared the proposed unbiased estimator with that of Kuk (1990 Kuk, A.Y.C. (1990). Asking sensitive questions inderectely. Biometrika 77:436–438.[Crossref], [Web of Science ®] , [Google Scholar]) and Franklin (1989 Franklin, L.A. (1989). A comparision of estimators for randomized response sampling with continuous distribution s from a dichotomous population. Commun. Stat. Theor. Methods 18:489–505.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]), and Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:3377–3380.[Crossref], [Web of Science ®] , [Google Scholar]) estimators. Relevant conditions are obtained in which the proposed estimator is more efficient than Kuk (1990 Kuk, A.Y.C. (1990). Asking sensitive questions inderectely. Biometrika 77:436–438.[Crossref], [Web of Science ®] , [Google Scholar]) and Franklin (1989 Franklin, L.A. (1989). A comparision of estimators for randomized response sampling with continuous distribution s from a dichotomous population. Commun. Stat. Theor. Methods 18:489–505.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) and Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:3377–3380.[Crossref], [Web of Science ®] , [Google Scholar]) estimators. The optimum estimator (OE) in the proposed class of estimators has been identified which finally depends on moments ratios of the scrambling variables. The variance of the optimum estimator has been obtained and compared with that of the Kuk (1990 Kuk, A.Y.C. (1990). Asking sensitive questions inderectely. Biometrika 77:436–438.[Crossref], [Web of Science ®] , [Google Scholar]) and Franklin (1989 Franklin, L.A. (1989). A comparision of estimators for randomized response sampling with continuous distribution s from a dichotomous population. Commun. Stat. Theor. Methods 18:489–505.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) estimator and Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:3377–3380.[Crossref], [Web of Science ®] , [Google Scholar]) estimator. It is interesting to mention that the “optimum estimator” of the class of estimators due to Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:3377–3380.[Crossref], [Web of Science ®] , [Google Scholar]) depends on the parameter π under investigation which limits the use of Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:3377–3380.[Crossref], [Web of Science ®] , [Google Scholar]) OE in practice while the proposed OE in this paper is free from such a constraint. The proposed OE depends only on the moments ratios of scrambling variables. This is an advantage over the Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:3377–3380.[Crossref], [Web of Science ®] , [Google Scholar]) estimator. Numerical illustrations are given in the support of the present study when the scrambling variables follow normal distribution. Theoretical and empirical results are very sound and quite illuminating in the favor of the present study.     

Universally optimal designs under interference models with and without block effects

The concept of neighbor designs was introduced and defined by Rees (1967 Rees, D.H. (1967). Some designs of use in serology. Biometrics 23:779–791.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) along with giving some methods of their construction. Henceforth, many methods of construction of neighbor designs as well as of their generalizations are available in the literature. However, there are only few results on their optimality. Therefore, the purpose of this article is to give an overview of study on this problem. Recent results on optimality of specified neighbor balanced designs under various interference models with block effects are presented and then these results are compared with respective models where block effects are not significant.     

Complete and complete moment convergence for i.i.d. random variables under exponential moment conditions

In this paper, we establish a complete convergence result and a complete moment convergence result for i.i.d. random variables under moment condition which is slightly weaker than the existence of the moment generating function. The main results extend and improve the related known results of Lanzinger (1998 Lanzinger, H. (1998). A Baum-Katz theorem for random variables under exponential moment conditions. Stat. Probab. Lett. 39(2):89–95.[Crossref], [Web of Science ®] , [Google Scholar]) and Gut and Stadtmüller (2011 Gut, A., Stadtmüller, U. (2011). An intermediate Baum-Katz theorem. Stat. Probab. Lett. 81(10):1486–1492.[Crossref], [Web of Science ®] , [Google Scholar]).     

An extension of almost sure central limit theorem for the maximum of stationary Gaussian random fields

Let X₁, X₂, … be a sequence of stationary standardized Gaussian random fields. The almost sure limit theorem for the maxima of stationary Gaussian random fields is established. Our results extend and improve the results in Csáki and Gonchigdanzan (2002 Csáki, E., Gonchigdanzan, K. (2002). Almost sure limit theorems for the maximum of stationary Gaussian sequences. Stat. Probab. Lett. 58:195–203.[Crossref], [Web of Science ®] , [Google Scholar]) and Choi (2010 Choi, H. (2010). Almost sure limit theorem for stationary Gaussian random fields. J. Korean Stat. Soc. 39:449–454.[Crossref], [Web of Science ®] , [Google Scholar]).     

A two-stage Land et al.'s randomized response model for estimating a rare sensitive attribute using Poisson distribution

The crux of this paper is to estimate the mean of the number of persons possessing a rare sensitive attribute based on the Mangat (1992 Mangat, N.S. (1992). Two stage reandomized response sampling procedure using unrelated question. J. Ind. Soc. Agric. Stat. 44(1):82–87. [Google Scholar]) randomization device by utilizing the Poisson distribution in survey sampling. It is shown that the proposed model is more efficient than Land et al. (2011 Land, M., Singh, S., Sedory, S.A. (2011). Estimation of a rare attribute using Poisson distribution. Statistics doi:10.1080/02331888.2010.524300[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) when the proportion of persons possessing a rare unrelated attribute is known. Properties of the proposed randomized response model have been studied along with recommendations. We have also extended the proposed model to stratified random sampling on the lines of Lee et al. (2013 Lee, G.S., Uhm, D., Kim, J.M. (2013). Estimation of a rare sensitive attribute in stratified sampling using Poisson distribution. Statistics 47(3):575–589.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]). It has been also shown that the proposed estimator is better than Lee et al.'s (2013 Lee, G.S., Uhm, D., Kim, J.M. (2013). Estimation of a rare sensitive attribute in stratified sampling using Poisson distribution. Statistics 47(3):575–589.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) estimator. Numerical illustrations are also given in support of the present study.     

A modified Hosmer–Lemeshow test for large data sets

The Hosmer–Lemeshow test is a widely used method for evaluating the goodness of fit of logistic regression models. But its power is much influenced by the sample size, like other chi-square tests. Paul, Pennell, and Lemeshow (2013 Paul, P., M. L. Pennell, and S. Lemeshow. 2013. Standardizing the power of the Hosmer–Lemeshow goodness of fit test in large data sets. Statistics in Medicine 32:67–80.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) considered using a large number of groups for large data sets to standardize the power. But simulations show that their method performs poorly for some models. In addition, it does not work when the sample size is larger than 25,000. In the present paper, we propose a modified Hosmer–Lemeshow test that is based on estimation and standardization of the distribution parameter of the Hosmer–Lemeshow statistic. We provide a mathematical derivation for obtaining the critical value and power of our test. Through simulations, we can see that our method satisfactorily standardizes the power of the Hosmer–Lemeshow test. It is especially recommendable for enough large data sets, as the power is rather stable. A bank marketing data set is also analyzed for comparison with existing methods.