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1.
Two-period crossover design is one of the commonly used designs in clinical trials. But, the estimation of treatment effect is complicated by the possible presence of carryover effect. It is known that ignoring the carryover effect when it exists can lead to poor estimates of the treatment effect. The classical approach by Grizzle (1965 Grizzle, J.E. (1965). The two-period change-over design and its use in clinical trials. Biometrics 21:467480. See Grizzle (1974) for corrections.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) consists of two stages. First, a preliminary test is conducted on carryover effect. If the carryover effect is significant, analysis is based only on data from period one; otherwise, analysis is based on data from both periods. A Bayesian approach with improper priors was proposed by Grieve (1985 Grieve, A.P. (1985). A Bayesian analysis of the two-period crossover design for clinical trials. Biometrics 41:979990.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) which uses a mixture of two models: a model with carryover effect and another without. The indeterminacy of the Bayes factor due to the arbitrary constant in the improper prior was addressed by assigning a minimally discriminatory value to the constant. In this article, we present an objective Bayesian estimation approach to the two-period crossover design which is also based on a mixture model, but using the commonly recommended Zellner–Siow g-prior. We provide simulation studies and a real data example and compare the numerical results with Grizzle (1965 Grizzle, J.E. (1965). The two-period change-over design and its use in clinical trials. Biometrics 21:467480. See Grizzle (1974) for corrections.[Crossref], [PubMed], [Web of Science ®] [Google Scholar])’s and Grieve (1985 Grieve, A.P. (1985). A Bayesian analysis of the two-period crossover design for clinical trials. Biometrics 41:979990.[Crossref], [PubMed], [Web of Science ®] [Google Scholar])’s approaches.  相似文献   

2.
Since the seminal paper of Ghirardato (1997 Ghirardato, P. 1997. On the independence for non-additive measures, with a Fubini theorem. Journal of Economic Theory 73:26191.[Crossref], [Web of Science ®] [Google Scholar]), it is known that Fubini theorem for non additive measures can be available only for functions as “slice-comonotonic” in the framework of product algebra. Later, inspired by Ghirardato (1997 Ghirardato, P. 1997. On the independence for non-additive measures, with a Fubini theorem. Journal of Economic Theory 73:26191.[Crossref], [Web of Science ®] [Google Scholar]), Chateauneuf and Lefort (2008 Chateauneuf, A., and J. P. Lefort. 2008. Some Fubini theorems on product σ-algebras for non-additive measures. International Journal of Approximate Reasoning 48:68696.[Crossref], [Web of Science ®] [Google Scholar]) obtained some Fubini theorems for non additive measures in the framework of product σ-algebra. In this article, we study Fubini theorem for non additive measures in the framework of g-expectation. We give some different assumptions that provide Fubini theorem in the framework of g-expectation.  相似文献   

3.
Let X1, X2, … be a sequence of stationary standardized Gaussian random fields. The almost sure limit theorem for the maxima of stationary Gaussian random fields is established. Our results extend and improve the results in Csáki and Gonchigdanzan (2002 Csáki, E., Gonchigdanzan, K. (2002). Almost sure limit theorems for the maximum of stationary Gaussian sequences. Stat. Probab. Lett. 58:195203.[Crossref], [Web of Science ®] [Google Scholar]) and Choi (2010 Choi, H. (2010). Almost sure limit theorem for stationary Gaussian random fields. J. Korean Stat. Soc. 39:449454.[Crossref], [Web of Science ®] [Google Scholar]).  相似文献   

4.
This article is concerned with the minimax estimation of a scale parameter under the quadratic loss function where the family of densities is location-scale type. We obtain results for the case when the scale parameter is bounded below by a known constant. Implications for the estimation of a lower-bounded scale parameter of an exponential distribution are presented under unknown location. Furthermore, classes of improved minimax estimators are derived for the restricted parameter using the Integral Expression for Risk Difference (IERD) approach of Kubokawa (1994 Kubokawa, T. (1994). A unified approach to improving equivariant estimators. Ann. Stat. 22:290299.[Crossref], [Web of Science ®] [Google Scholar]). These classes are shown to include some existing estimators from literature.  相似文献   

5.
The aim of this article is the construction of the test statistic for the detection of changes in vector autoregressive (AR) models where both AR parameters and the variance matrix of the error term are the subjects of a change. The approximating distribution of the proposed statistic is the Gumbel distribution. The proof stands on the approximation of weakly dependent random vectors by independent ones and by application of Horváth’s extension of Darling-Erdös extremal result for random vectors, see Darling and Erdös (1956) Darling, D.A., Erdös, P. (1956). A limit theorem for the maximum of normalized sums of independent random variables. Duke Math. J. 23:143155.[Crossref], [Web of Science ®] [Google Scholar] and Horváth (1993) Horváth, L. (1993). The maximum likelihood method for testing changes in the parameters of normal observations. Ann. Stat. 21(2):671680.[Crossref], [Web of Science ®] [Google Scholar]. The test statistic is a modification of the likelihood ratio.  相似文献   

6.
The objective of this paper is to study U-type designs for Bayesian non parametric response surface prediction under correlated errors. The asymptotic Bayes criterion is developed in terms of the asymptotic approach of Mitchell et al. (1994 Mitchell, T., Sacks, J., Ylvisaker, D. (1994). Asymptotic Bayes criteria for nonparametric response surface design. Ann. Stat. 22:634651.[Crossref], [Web of Science ®] [Google Scholar]) for a more general covariance kernel proposed by Chatterjee and Qin (2011 Chatterjee, K., Qin, H. (2011). Generalized discrete discrepancy and its applications in experimental designs. J. Stat. Plann. Inference 141:951960.[Crossref], [Web of Science ®] [Google Scholar]). A relationship between the asymptotic Bayes criterion and other criteria, such as orthogonality and aberration, is then developed. A lower bound for the criterion is also obtained, and numerical results show that this lower bound is tight. The established results generalize those of Yue et al. (2011 Yue, R.X., Qin, H., Chatterjee, K. (2011). Optimal U-type design for Bayesian nonparametric multiresponse prediction. J. Stat. Plann. Inference 141:24722479.[Crossref], [Web of Science ®] [Google Scholar]) from symmetrical case to asymmetrical U-type designs.  相似文献   

7.
This paper proposes a bivariate version of the univariate discrete generalized geometric distribution considered by Gómez–Déniz (2010 Gómez–Déniz, E. (2010). Another generalization of the geometric distribution. Test 19:399415.[Crossref], [Web of Science ®] [Google Scholar]). The proposed bivariate distribution can have a positive or negative correlation coefficient which can be used for modeling bivariate-dependent count data. After discussing some of its properties, maximum likelihood estimation is discussed. Two illustrative examples are given for fitting and demonstrating the usefulness of the new bivariate distribution proposed here.  相似文献   

8.
The complication in analyzing tumor data is that the tumors detected in a screening program tend to be slowly progressive tumors, which is the so-called left-truncated sampling that is inherent in screening studies. Under the assumption that all subjects have the same tumor growth function, Ghosh (2008 Ghosh, D. (2008). Proportional hazards regression for cancer studies. Biometrics 64:141148.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) developed estimation procedures for the Cox proportional hazards model. Shen (2011a Shen, P.-S. (2011a). Proportional hazards regression for cancer screening data. J. Stat. Comput. Simul. 18:367377.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) demonstrated that Ghosh (2008 Ghosh, D. (2008). Proportional hazards regression for cancer studies. Biometrics 64:141148.[Crossref], [PubMed], [Web of Science ®] [Google Scholar])'s approach can be extended to the case when each subject has a specific growth function. In this article, under linear transformation model, we present a general framework to the analysis of data from cancer screening studies. We developed estimation procedures under linear transformation model, which includes Cox's model as a special case. A simulation study is conducted to demonstrate the potential usefulness of the proposed estimators.  相似文献   

9.
Gupta and Kirmani (2008 Gupta, R.C., Kirmani, S.N.U.A. (2008). Characterization based on convex conditional mean function. J. Stat. Plann Inference. 138:964970.[Crossref], [Web of Science ®] [Google Scholar]) showed that the convex conditional mean function (CCMF) characterizes the distribution function completely. In this paper, we introduce a consistent estimator of CCMF and call it empirical convex conditional mean function (ECCMF). Then we construct a simple consistent test of fit based on the integrated squared difference between ECCMF and CCMF. The theoretical and asymptotic properties of the estimator ECCMF and the proposed test statistic are studied. The performance of the constructed test is investigated under different distributions using simulations.  相似文献   

10.
The present paper suggests an interesting and useful ramification of the unrelated randomized response model due to Pal and Singh (2012 Pal, S., and S. Singh. 2012. A new unrelated question randomized response model. Statistics 46 (1):99109.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) [A new unrelated question randomized response model. Statistics 46 (1), 99–109] that can be used for any sampling scheme. We have shown theoretically and numerically that the proposed model is more efficient than Pal and Singh (2012 Pal, S., and S. Singh. 2012. A new unrelated question randomized response model. Statistics 46 (1):99109.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) model.  相似文献   

11.
The testing of the stratum effects in the Cox model is an important and commonly asked question in medical research as well as in many other fields. In this paper, we will discuss the problem where one observes interval-censored failure time data and generalize the procedure given in Sun and Yang (2000 Sun, J., and I. Yang. 2000. Nonparametric test for stratum effects in the cox model. Lifetime Data Analysis 6:32130.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) for right-censored data. The asymptotic distribution of the new test statistic is established and the simulation study conducted for the evaluation of the finite sample properties of the method suggests that the generalized procedure seems to work well for practical situations. An application is provided.  相似文献   

12.
We consider the problem of estimation of a finite population proportion (P) related to a sensitive attribute under Warner's (1965 Warner, S.L. (1965). Randomized response: A survey technique for eliminating evasive answer bias. J. Am. Stat. Assoc. 60:6369.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) randomized response plan and the unrelated question plan due to Horvitz et al. (1967 Warner, S.L. (1965). Randomized response: A survey technique for eliminating evasive answer bias. J. Am. Stat. Assoc. 60:6369.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) and prove that for a given probability sampling design, given any linear unbiased estimator (LUE) of P based on Warner's (1965 Warner, S.L. (1965). Randomized response: A survey technique for eliminating evasive answer bias. J. Am. Stat. Assoc. 60:6369.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) plan with any given value of the plan parameter, there exists an LUE of P based on the unrelated question plan with a uniformly smaller variance for suitable choices of the plan parameters. Assuming that only the attribute is sensitive but its complement is innocuous, the same is also shown to be true when the plan parameters for the two plans are so chosen so that both offer the same specified level of privacy.  相似文献   

13.
In this article, we discuss the method of linear kernel quantile estimator proposed by Parzen (1979 Parzen, E. (1979). Nonparametric statistical data modeling. J. Amer. Statist. Assoc. 74:105121.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]). We establish a Bahadur representation in sense of almost surely convergence with the rate log? αn under the case of S-mixing random variable sequence which was proposed by Berkes (2009 Berkes, I., Hörmann, S., (2009). Asymptotic results for the itpirical process of stationary sequences. Stoch. Process. Their Applic. 119:12981324.[Crossref], [Web of Science ®] [Google Scholar]). We also obtain the strong consistence of this estimator and its convergence rate.  相似文献   

14.
This paper aimed at providing an efficient new unbiased estimator for estimating the proportion of a potentially sensitive attribute in survey sampling. The suggested randomization device makes use of the means, variances of scrambling variables, and the two scalars lie between “zero” and “one.” Thus, the same amount of information has been used at the estimation stage. The variance formula of the suggested estimator has been obtained. We have compared the proposed unbiased estimator with that of Kuk (1990 Kuk, A.Y.C. (1990). Asking sensitive questions inderectely. Biometrika 77:436438.[Crossref], [Web of Science ®] [Google Scholar]) and Franklin (1989 Franklin, L.A. (1989). A comparision of estimators for randomized response sampling with continuous distribution s from a dichotomous population. Commun. Stat. Theor. Methods 18:489505.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]), and Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) estimators. Relevant conditions are obtained in which the proposed estimator is more efficient than Kuk (1990 Kuk, A.Y.C. (1990). Asking sensitive questions inderectely. Biometrika 77:436438.[Crossref], [Web of Science ®] [Google Scholar]) and Franklin (1989 Franklin, L.A. (1989). A comparision of estimators for randomized response sampling with continuous distribution s from a dichotomous population. Commun. Stat. Theor. Methods 18:489505.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) and Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) estimators. The optimum estimator (OE) in the proposed class of estimators has been identified which finally depends on moments ratios of the scrambling variables. The variance of the optimum estimator has been obtained and compared with that of the Kuk (1990 Kuk, A.Y.C. (1990). Asking sensitive questions inderectely. Biometrika 77:436438.[Crossref], [Web of Science ®] [Google Scholar]) and Franklin (1989 Franklin, L.A. (1989). A comparision of estimators for randomized response sampling with continuous distribution s from a dichotomous population. Commun. Stat. Theor. Methods 18:489505.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) estimator and Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) estimator. It is interesting to mention that the “optimum estimator” of the class of estimators due to Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) depends on the parameter π under investigation which limits the use of Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) OE in practice while the proposed OE in this paper is free from such a constraint. The proposed OE depends only on the moments ratios of scrambling variables. This is an advantage over the Singh and Chen (2009 Singh, S., Chen, C.C. (2009). Utilization of higher order moments of scrambling variables in randomized response sampling. J. Stat. Plann. Inference. 139:33773380.[Crossref], [Web of Science ®] [Google Scholar]) estimator. Numerical illustrations are given in the support of the present study when the scrambling variables follow normal distribution. Theoretical and empirical results are very sound and quite illuminating in the favor of the present study.  相似文献   

15.
Repeated measurement designs are widely used in medicine, pharmacology, animal sciences, and psychology. In this paper the works of Iqbal and Tahir (2009 Iqbal, I., and M. H. Tahir. 2009. Circular strongly balanced repeated measurements designs. Communications in Statistics—Theory and Methods 38:368696.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) and Iqbal, Tahir, and Ghazali (2010 Iqbal, I., M. H. Tahir, and S. S. A. Ghazali. 2010. Circular first- and second-order balanced repeated measurements designs. Communications in Statistics—Theory and Methods 39:22840.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) are generalized for the construction of circular-balanced and circular strongly balanced repeated measurements designs through the method of cyclic shifts for three periods.  相似文献   

16.
In this paper we propose an extension of the generalized half-normal distribution studied in Cooray and Ananda (Commun Stat 37:1323–1337, 2008). This new distribution is defined by considering the quotient of two random variables, the one in the numerator being a generalized half normal distribution and the one in the denominator being a power of the uniform distribution on \((0,1)\) , respectively. The resulting distribution has greater kurtosis than the generalized half normal distribution. The density function of this more general distribution is derived jointly with some of its properties and moments. We discuss stochastic representation, maximum likelihood and moments estimation. Applications to real data sets are reported revealing that the proposed distribution can fit real data better than the slashed half-normal, generalized half-normal and Birnbaum–Saunders distributions.  相似文献   

17.
Recently, Feizjavadian and Hashemi (2015 Feizjavadian, S.H., Hashemi, R. (2015). Mean residual weighted versus the length-biased Rayleigh distribution. J. Stat. Comput. Simul. 85:28232838.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar]) introduced and studied the mean residual weighted (MRW) distribution as an alternative to the length-biased distribution, by using the concepts of the mean residual lifetime and the cumulative residual entropy (CRE). In this article, a new sequence of weighted distributions is introduced based on the generalized CRE. This sequence includes the MRW distribution. Properties of this sequence are obtained generalizing and extending previous results on the MRW distribution. Moreover, expressions for some known distributions are given, and finite mixtures between the new sequence of weighted distributions and the length-biased distribution are studied. Numerical examples are given to illustrate the new results.  相似文献   

18.
This article recasts the optimal allocations of coverage limits for two independent random losses. Under some regularity conditions on the two concerned probability density functions, we build the sufficient and necessary condition for the existence of the optimal allocation of coverage limits, and derive the optimal allocation whenever they do exist. The results supplement Lu and Meng (2011 Lu, Z.Y., Meng, L.L. (2011). Stochastic comparisons for allocations of upper limits and deductibles with applications. Insur.: Math. Econ. 48:338343.[Crossref], [Web of Science ®] [Google Scholar], Proposition 5.2) and Hu and Wang (2014 Hu, S., Wang, R. (2014). Stochastic comparisons and optimal allocation for policy limits and deductibles. Commun. Stat. – Theory Methods 43:151164.[Taylor &; Francis Online], [Web of Science ®] [Google Scholar], Theorem 5.1).  相似文献   

19.
Credibility formula has been developed in many fields of actuarial sciences. Based upon Payandeh (2010 Payandeh, A.T. (2010). A new approach to the credibility formula. Insur.: Math. Econ. 46(2):334338.[Crossref], [Web of Science ®] [Google Scholar]), this article extends concept of credibility formula to relatively premium of a given rate-making system. More precisely, it calculates Payandeh’s (2010 Payandeh, A.T. (2010). A new approach to the credibility formula. Insur.: Math. Econ. 46(2):334338.[Crossref], [Web of Science ®] [Google Scholar]) credibility factor for zero-inflated Poisson gamma distributions with respect to several loss functions. A comparison study has been given.  相似文献   

20.
This paper treats the problem of stochastic comparisons for the extreme order statistics arising from heterogeneous beta distributions. Some sufficient conditions involved in majorization-type partial orders are provided for comparing the extreme order statistics in the sense of various magnitude orderings including the likelihood ratio order, the reversed hazard rate order, the usual stochastic order, and the usual multivariate stochastic order. The results established here strengthen and extend those including Kochar and Xu (2007 Kochar, S.C., Xu, M. (2007). Stochastic comparisons of parallel systems when components have proportional hazard rates. Probab. Eng. Inf. Sci. 21:597609.[Crossref], [Web of Science ®] [Google Scholar]), Mao and Hu (2010 Mao, T., Hu, T. (2010). Equivalent characterizations on orderings of order statistics and sample ranges. Probab. Eng. Inf. Sci. 24:245262.[Crossref], [Web of Science ®] [Google Scholar]), Balakrishnan et al. (2014 Balakrishnan, N., Barmalzan, G., Haidari, A. (2014). On usual multivariate stochastic ordering of order statistics from heterogeneous beta variables. J. Multivariate Anal. 127:147150.[Crossref], [Web of Science ®] [Google Scholar]), and Torrado (2015 Torrado, N. (2015). On magnitude orderings between smallest order statistics from heterogeneous beta distributions. J. Math. Anal. Appl. 426:824838.[Crossref], [Web of Science ®] [Google Scholar]). A real application in system assembly and some numerical examples are also presented to illustrate the theoretical results.  相似文献   

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