Modified Wilcoxon–Mann–Whitney Test and Power Against Strong Null

The Wilcoxon–Mann–Whitney (WMW) test is a popular rank-based two-sample testing procedure for the strong null hypothesis that the two samples come from the same distribution. A modified WMW test, the Fligner–Policello (FP) test, has been proposed for comparing the medians of two populations. A fact that may be under-appreciated among some practitioners is that the FP test can also be used to test the strong null like the WMW. In this article, we compare the power of the WMW and FP tests for testing the strong null. Our results show that neither test is uniformly better than the other and that there can be substantial differences in power between the two choices. We propose a new, modified WMW test that combines the WMW and FP tests. Monte Carlo studies show that the combined test has good power compared to either the WMW and FP test. We provide a fast implementation of the proposed test in an open-source software. Supplementary materials for this article are available online.     

A modified Mack–Wolfe test for the umbrella alternative problem

ABSTRACT

The Mack–Wolfe test is the most frequently used non parametric procedure for the umbrella alternative problem. In this paper, modifications of the Mack–Wolfe test are proposed for both known peak and unknown peak umbrellas. The exact mean and variance of the proposed tests in the null hypothesis are also derived. We compare these tests with some of the existing tests in terms of the type I error rate and power. In addition, a real data example is presented.     

Hypothesis testing in smoothing spline models

Nonparametric regression models are often used to check or suggest a parametric model. Several methods have been proposed to test the hypothesis of a parametric regression function against an alternative smoothing spline model. Some tests such as the locally most powerful (LMP) test by Cox et al. (Cox, D., Koh, E., Wahba, G. and Yandell, B. (1988). Testing the (parametric) null model hypothesis in (semiparametric) partial and generalized spline models. Ann. Stat., 16, 113–119.), the generalized maximum likelihood (GML) ratio test and the generalized cross validation (GCV) test by Wahba (Wahba, G. (1990). Spline models for observational data. CBMS-NSF Regional Conference Series in Applied Mathematics, SIAM.) were developed from the corresponding Bayesian models. Their frequentist properties have not been studied. We conduct simulations to evaluate and compare finite sample performances. Simulation results show that the performances of these tests depend on the shape of the true function. The LMP and GML tests are more powerful for low frequency functions while the GCV test is more powerful for high frequency functions. For all test statistics, distributions under the null hypothesis are complicated. Computationally intensive Monte Carlo methods can be used to calculate null distributions. We also propose approximations to these null distributions and evaluate their performances by simulations.     

Testing for spherical symmetry via the empirical characteristic function

Kolmogorov–Smirnov-type and Cramér–von Mises-type goodness-of-fit tests are proposed for the null hypothesis that the distribution of a random vector X is spherically symmetric. The test statistics utilize the fact that X has a spherical symmetric distribution if, and only if, the characteristic function of X is constant over surfaces of spheres centred at the origin. Both tests come in convenient forms that are straightforwardly applicable with the computer. The asymptotic null distribution of the test statistics as well as the consistency of the tests is investigated under general conditions. Since both the finite sample and the asymptotic null distribution depend on the unknown distribution of the Euclidean norm of X, a conditional Monte Carlo procedure is used to actually carry out the tests. Results on the behaviour of the test in finite-samples are included along with a real-data example.     

Testing the Martingale Hypothesis

We propose new tests of the martingale hypothesis based on generalized versions of the Kolmogorov–Smirnov and Cramér–von Mises tests. The tests are distribution-free and allow for a weak drift in the null model. The methods do not require either smoothing parameters or bootstrap resampling for their implementation and so are well suited to practical work. The article develops limit theory for the tests under the null and shows that the tests are consistent against a wide class of nonlinear, nonmartingale processes. Simulations show that the tests have good finite sample properties in comparison with other tests particularly under conditional heteroscedasticity and mildly explosive alternatives. An empirical application to major exchange rate data finds strong evidence in favor of the martingale hypothesis, confirming much earlier research.     

Testing for empty sets when misclassifications may be present

A test for empty sets is described. This new test is suitable for testing for mutual exclusivity, sets being nested, and many other configurations. It might be hypothesized that two medical conditions do not both occur in individuals. This can be expressed as an empty intersection of the two sets of people with each condition. An important feature of the test is the incorporation of misclassification rates into the analysis. The test utilizes the potential misclassifications for false designations in the sets that are hypothesized to be empty. The test is quite powerful. When the null hypothesis is rejected, follow-up tests on one or more sets that are included in the null hypothesis can be performed using the same new test. MatLab code is supplied.     

The Equivalence of Two Proportions Revisited

The classic conditional test for checking that the difference between two independent proportions is not null may not be appropriate in many circumstances. Dunnett & Gent (1977) showed that in clinical trials, in studies of drugs, etc, the aim is to prove the practical equality (equivalence) of both proportions. On other occasions the aim may be the opposite: i.e. to prove that the two proportions are substantially different (biologically significant). Both cases are usually solved by two one-sided tests (TOST test). In this article, this procedure is shown to be conservative and two true two-sided tests for each case are proposed.     

Some count-based nonparametric tests for circular symmetry of a bivariate distribution

In this paper, we revisit the problem of testing of the hypothesis of circular symmetry of a bivariate distribution. We propose some nonparametric tests based on sector counts. These include tests based on chi-square goodness-of-fit test, the classical likelihood ratio, mean deviation, and the range. The proposed tests are easy to implement and the exact null distributions for small sample sizes of the test statistics are obtained. Two examples with small and large data sets are given to illustrate the application of the tests proposed. For small and moderate sample sizes, the performances of the proposed tests are evaluated using empirical powers (empirical sizes are also reported). Also, we evaluate the performance of these count-based tests with adaptations of several well-known tests such as the Kolmogorov–Smirnov-type tests, tests based on kernel density estimator, and the Wilcoxon-type tests. It is observed that among the count-based tests the likelihood ratio test performs better.     

Weighted Mean Survival Test Statistics: a Class of Distance Tests for Censored Survival Data

A class of test statistics is introduced which is sensitive against the alternative of stochastic ordering in the two-sample censored data problem. The test statistics for evaluating a cumulative weighted difference in survival distributions are developed while taking into account the imbalances in base-line covariates between two groups. This procedure can be used to test the null hypothesis of no treatment effect, especially when base-line hazards cross and prognostic covariates need to be adjusted. The statistics are semiparametric, not rank based, and can be written as integrated weighted differences in estimated survival functions, where these survival estimates are adjusted for covariate imbalances. The asymptotic distribution theory of the tests is developed, yielding test procedures that are shown to be consistent under a fixed alternative. The choice of weight function is discussed and relies on stability and interpretability considerations. An example taken from a clinical trial for acquired immune deficiency syndrome is presented.     

A Class of Permutation Tests for the Equality of Two Marginal Survival Functions Using Paired Censored Data

We studied several test statistics for testing the equality of marginal survival functions of paired censored data. The null distribution of the test statistics was approximated by permutation. These tests do not require explicit modeling or estimation of the within-pair correlation, accommodate both paired data and singletons, and the computation is straightforward with most statistical software. Numerical studies showed that these tests have competitive size and power performance. One test statistic has higher power than previously published test statistics when the two survival functions under comparison cross. We illustrate use of these tests in a propensity score matched dataset.     

Optimal testing in a three way anova model

We consider likelihood ratio, score and Wald tests for a three-way random effects ANOVA model. Competitor tests are compared using criteria such as small sample power, asymptotic relative efficiency, and convenient null distribution. The final choice is between a new test and two tests long used in practice.     

Maximum Average-Power (MAP) Tests

The objective of this article is to propose and study frequentist tests that have maximum average power, averaging with respect to some specified weight function. First, some relationships between these tests, called maximum average-power (MAP) tests, and most powerful or uniformly most powerful tests are presented. Second, the existence of a maximum average-power test for any hypothesis testing problem is shown. Third, an MAP test for any hypothesis testing problem with a simple null hypothesis is constructed, including some interesting classical examples. Fourth, an MAP test for a hypothesis testing problem with a composite null hypothesis is discussed. From any one-parameter exponential family, a commonly used UMPU test is shown to be also an MAP test with respect to a rich class of weight functions. Finally, some remarks are given to conclude the article.     

Adaptive tests of regression functions via multiscale generalized likelihood ratios

Many applications of nonparametric tests based on curve estimation involve selecting a smoothing parameter. The author proposes an adaptive test that combines several generalized likelihood ratio tests in order to get power performance nearly equal to whichever of the component tests is best. She derives the asymptotic joint distribution of the component tests and that of the proposed test under the null hypothesis. She also develops a simple method of selecting the smoothing parameters for the proposed test and presents two approximate methods for obtaining its P‐value. Finally, she evaluates the proposed test through simulations and illustrates its application to a set of real data.     

Parameter Change Test for Poisson Autoregressive Models

In this paper, we consider the problem of testing for a parameter change in Poisson autoregressive models. We suggest two types of cumulative sum (CUSUM) tests, namely, those based on estimates and residuals. We first demonstrate that the conditional maximum likelihood estimator (CMLE) is strongly consistent and asymptotically normal and then construct the CMLE‐based CUSUM test. It is shown that under regularity conditions, its limiting null distribution is a function of independent Brownian bridges. Next, we construct the residual‐based CUSUM test and derive its limiting null distribution. Simulation results are provided for illustration. A real‐data analysis is performed on data for polio incidence and campylobacteriosis infections.     

On choosing between two nonlinear models estimated robustly. Some Monte Carlo evidence

The article considers the problem of choosing between two (possibly) nonlinear models that have been fitted to the same data using M-estimation methods. An asymptotically normally distributed test statistic that takes into account the fact that the models are fitted robustly is given. The new procedure is compared with other test statistics using a Monte Carlo study. We found that the presence of a competitive model either in the null or the alternative hipothesis affects the distributional properties of the tests, and that in the case that the data contains outlying observations the new procedure had a significantly higher power than the rest of the tests.     

Adaptive Neyman's smooth tests of homogeneity of two samples of survival data

The problem of testing whether two samples of possibly right-censored survival data come from the same distribution is considered. The aim is to develop a test which is capable of detection of a wide spectrum of alternatives. A new class of tests based on Neyman's embedding idea is proposed. The null hypothesis is tested against a model where the hazard ratio of the two survival distributions is expressed by several smooth functions. A data-driven approach to the selection of these functions is studied. Asymptotic properties of the proposed procedures are investigated under fixed and local alternatives. Small-sample performance is explored via simulations which show that the power of the proposed tests appears to be more robust than the power of some versatile tests previously proposed in the literature (such as combinations of weighted logrank tests, or Kolmogorov–Smirnov tests).     

Gap-ratio goodness of fit tests for weibull or extreme value distribution assumptions with left or right censored data

With data collection in environmental science and bioassay, left censoring because of nondetects is a problem. Similarly in reliability and life data analysis right censoring frequently occurs. There is a need for goodness of fit tests that can adapt to left or right censored data and be used to check important distributional assumptions without becoming too difficult to regularly implement in practice. A new test statistic is derived from a plot of the standardized spacings between the order statistics versus their ranks. Any linear or curvilinear pattern is evidence against the null distribution. When testing the Weibull or extreme value null hypothesis this statistic has a null distribution that is approximately F for most combinations of sample size and censoring of practical interest. Our statistic is compared to the Mann-Scheuer-Fertig statistic which also uses the standardized spacings between the order statistics. The results of a simulation study show the two tests are competitive in terms of power. Although the Mann-Scheuer-Fertig statistic is somewhat easier to compute, our test enjoys advantages in the accuracy of the F approximation and the availability of a graphical diagnostic.     

An Affine-Invariant Generalization of the Wilcoxon Signed-Rank Test for the Bivariate Location Problem

This paper proposes an affine‐invariant test extending the univariate Wilcoxon signed‐rank test to the bivariate location problem. It gives two versions of the null distribution of the test statistic. The first version leads to a conditionally distribution‐free test which can be used with any sample size. The second version can be used for larger sample sizes and has a limiting χ₂² distribution under the null hypothesis. The paper investigates the relationship with a test proposed by Jan & Randles (1994). It shows that the Pitman efficiency of this test relative to the new test is equal to 1 for elliptical distributions but that the two tests are not necessarily equivalent for non‐elliptical distributions. These facts are also demonstrated empirically in a simulation study. The new test has the advantage of not requiring the assumption of elliptical symmetry which is needed to perform the asymptotic version of the Jan and Randles test.     

The Use of Permutation Tests for Variance Components in Linear Mixed Models

Standard asymptotic chi-square distribution of the likelihood ratio and score statistics under the null hypothesis does not hold when the parameter value is on the boundary of the parameter space. In mixed models it is of interest to test for a zero random effect variance component. Some available tests for the variance component are reviewed and a new test within the permutation framework is presented. The power and significance level of the different tests are investigated by means of a Monte Carlo simulation study. The proposed test has a significance level closer to the nominal one and it is more powerful.