An MEP.2 plan in 3 factorial experiment and its probability of correct identification

The present work consider the problem of constructing search designs for searching at most two active hidden two-factor interactions in 3ⁿ factorial setup under the assumption that the three-factor and higher-order interactions are negligible. The designs presented here are also capable of estimating all the main effects, general mean and the effects of identified active two-factor interactions. The performance of the designs has been studied in the noisy case by computing probability of correct identification.     

On some new search designs for 2m factorial experiments

In this paper, we obtain search designs with reasonably small number of treatments which permit the estimation of the general mean and main effects and search of one more unknown possible nonzero effect among two and three factor interactions in 2^m factorial experiments, 3 ? m ? 8.     

Some new factor screening designs using the search linear model

Factor screening designs for searching two and three effective factors using the search linear model are discussed. The construction of such factor screening designs involved finding a fraction with small number of treatments of a 2^m factorial experiment having the property P_2t (no 2t columns are linearly dependent) for t=2 and 3. A ‘Packing Problem’ is introduced in this connection. A complete solution of the problem in one case and partial solutions for the other cases are presented. Many practically useful new designs are listed.     

On some optimal fractional 2m factorial designs of resolution V

This paper presents the trace of the covariance matrix of the estimates of effects based on a fractional 2^m factorial (2^m-FF) design T of resolution V for the following two cases: One is the case where T is constructed by adding some restricted assemblies to an orthogonal array. The other is one where T is constructed by removing some restricted assemblies from an orthogonal array of index unity. In the class of 2^m-FF designs of resolution V considered here, optimal designs with respect to the trace criterion, i.e. A-optimal, are presented for m = 4, 5, and 6 and for a range of practical values of N (the total number of assemblies). Some of them are better than the corresponding A-optimal designs in the class of balanced fractional 2^m factorial designs of resolution V obtained by Srivastava and Chopra (1971b) in such a sense that the trace of the covariance matrix of the estimates is small.     

A series of single array 2m factorial search designs for even m

By means of a search design one is able to search for and estimate a small set of non‐zero elements from the set of higher order factorial interactions in addition to estimating the lower order factorial effects. One may be interested in estimating the general mean and main effects, in addition to searching for and estimating a non‐negligible effect in the set of 2‐ and 3‐factor interactions, assuming 4‐ and higher‐order interactions are all zero. Such a search design is called a ‘main effect plus one plan’ and is denoted by MEP.1. Construction of such a plan, for 2^m factorial experiments, has been considered and developed by several authors and leads to MEP.1 plans for an odd number m of factors. These designs are generally determined by two arrays, one specifying a main effect plan and the other specifying a follow‐up. In this paper we develop the construction of search designs for an even number of factors m, m≠6. The new series of MEP.1 plans is a set of single array designs with a well structured form. Such a structure allows for flexibility in arriving at an appropriate design with optimum properties for search and estimation.     

Comparisons of search designs using search probabilities

Search designs are considered for searching and estimating one nonzero interaction from the two and three factor interactions under the search linear model. We compare three 12-run search designs D1, D2, and D3, and three 11-run search designs D4, D5, and D6, for a 2⁴ factorial experiment. Designs D2 and D3 are orthogonal arrays of strength 2, D1 and D4 are balanced arrays of full strength, D5 is a balanced array of strength 2, and D6 is obtained from D3 by deleting the duplicate run. Designs D4 and D5 are also obtained by deleting a run from D1 and D2, respectively. Balanced arrays and orthogonal arrays are commonly used factorial designs in scientific experiments. “Search probabilities” are calculated for the comparison of search designs. Three criteria based on search probabilities are presented to determine the design which is most likely to identify the nonzero interaction. The calculation of these search probabilities depends on an unknown parameter ρ which has a signal-to-noise ratio form. For a given value of ρ, Criteria I and II are newly proposed in this paper and Criteria III is given in Shirakura et al. (Ann. Statist. 24 (6) (1996) 2560). We generalize Criteria I–III for all values of ρ so that the comparison of search designs can be made without requiring a specific value of ρ. We have developed simplified methods for comparing designs under these three criteria for all values of ρ. We demonstrate, under all three criteria, that the balanced array D1 is more likely to identify the nonzero interaction than the orthogonal arrays D2 and D3, and the design D4 is more likely to identify the nonzero interaction than the designs D5 and D6.The methods of comparing designs developed in this paper are applicable to other factorial experiments for searching one nonzero interaction of any order.     

2 m 4 n designs with resolution III or IV containing clear two-factor interaction components

The orthogonal arrays with mixed levels have become widely used in fractional factorial designs. It is highly desirable to know when such designs with resolution III or IV have clear two-factor interaction components (2fic’s). In this paper, we give a complete classification of the existence of clear 2fic’s in regular 2 ^m 4 ⁿ designs with resolution III or IV. The necessary and sufficient conditions for a 2 ^m 4 ⁿ design to have clear 2fic’s are given. Also, 2 ^m 4 ⁿ designs of 32 runs with the most clear 2fic’s are given for n = 1,2.      

Saturated main-effect designs for factorial experiments

The results of a computer search for saturated designs for 2ⁿ factorial experiments with n runs is reported, (where n = 2 mod 4). A complete search of the design space is avoided by focussing on designs constructed from cyclic generators. A method of searching quickly for the best generators is given. The resulting designs are as good as, and sometimes better than, designs obtained via search algorithms reported in the literature. The addition of a further factor having three levels is also considered. Here, too, a complete search is avoided by restricting attention to the most efficient part of the design space under p-efficiency.     

Some results on constructing two-level block designs with general minimum lower order confounding

Block designs are widely used in experimental situations where the experimental units are heterogeneous. The blocked general minimum lower order confounding (B-GMC) criterion is suitable for selecting optimal block designs when the experimenters have some prior information on the importance of ordering of the treatment factors. This paper constructs B-GMC 2^{n ? m}: 2^r designs with 5 × 2^l/16 + 1 ? n ? (N ? 2^l) < 2^{l ? 1} for l(r + 1 ? l ? n ? m ? 1), where 2^{n ? m}: 2^r denotes a two-level regular block design with N = 2^{n ? m} runs, n treatment factors, and 2^r blocks. With suitable choice of the blocking factors, each B-GMC block design has a common specific structure. Some examples illustrate the simple and effective construction method.     

Construction of uniform designs for mixture experiments with complex constraints

Abstract

Mixture experiments have attracted increasingly attention due to their great practical value in production and living, while uniform designs over irregular experimental regions have become a hot topic in the area of experimental designs in the past two decades. Noting that the experimental region of a mixture experiment with q components under some constraints is in fact a (q ? 1)-dimensional geometry, this article proposes a new method for searching nearly uniform designs for mixture experiments with any complex constraints. Two examples with some tables and figures are given to illustrate this method.     

New light on fractional 2m factorial designs

New fractional 2^m factorial designs obtained by assigning factors to fractions of m columns of new saturated two symbol orthogonal arrays which are not isomorphic to the usual ones are proposed. Contrary to the usual assignment, examples show that some main effects are not totally but partially confounded with several two-factor interactions. Moreover, the recovery of the former from such partial confounding is possible in some cases by eliminating the latter.     

Main effect plan for 2m factorials which allow search and estimation of one unknown effect

In this paper, we discuss resolution III plans for 2^m factorial experiments which have an additional property. We relax the classical assumption that all the interactions are negligible by assuming that (at most) one of them may be nonnegligible. Which interaction is nonnegligible is unknown. We discuss designs which allow the search and estimation of this interaction, along with the estimation of the general mean and the main effects as in the classical resolution III designs.     

Search designs for 2m factorials derived from balanced arrays of strength 2(l+1) and ad-optimal search designs

We consider a search design for the 2^m type such that at most knonnegative effects can be searched among (l+1)-factor interactions and estimated along with the effects up to l- factor interactions, provided (l+1)-factor and higher order interactions are negligible except for the k effects. We investigate some properties of a search design which is yielded by a balanced 2^m design of resolution 2l+1 derived from a balanced array of strength 2(l+1). A necessary and sufficient condition for the balanced design of resolution 2l+1 to be a search design for k=1 is given. Optimal search designs for k=1 in the class of the balanced 2^m designs of resolution V (l=2), with respect to the AD-optimality criterion given by Srivastava (1977), with N assemblies are also presented, where the range of (m,N) is (m=6; 28≤N≤41), (m=7; 35≤N≤63) and (m=8; 44≤N≤74).     

A nonparametric procedure for the analysis of balanced crossover designs

The authors propose nonparametric tests for the hypothesis of no direct treatment effects, as well as for the hypothesis of no carryover effects, for balanced crossover designs in which the number of treatments equals the number of periods p, where p ≥ 3. They suppose that the design consists of n replications of balanced crossover designs, each formed by m Latin squares of order p. Their tests are permutation tests which are based on the n vectors of least squares estimators of the parameters of interest obtained from the n replications of the experiment. They obtain both the exact and limiting distribution of the test statistics, and they show that the tests have, asymptotically, the same power as the F‐ratio test.     

2m − p compromise plans with strongly clear specified main effects and two-factor interactions

This article studies two-level strongly clear compromise plans. We derive some necessary conditions for the existence of four classes of two-level strongly clear compromise plans which allow the estimations of some specified main effects and two-factor interactions, with the assumption that the fourth- or higher-order effects are negligible. Also, some methods for constructing 2^{m ? p} strongly clear compromise plans are introduced.     

A lower bound for the centred L 2-discrepancy on combined designs under the asymmetric factorials

The foldover is a useful technique in the construction of two-level factorial designs for follow-up experiments. To search an optimal foldover plans is an important issue. In this paper, for a set of asymmetric fractional factorials such as the original designs, a lower bound for centred L ₂-discrepancy of combined designs under a general foldover plan is obtained, which can be used as a benchmark for searching optimal foldover plans. All of our results are the extended ones of Ou et al. [Lower bounds of various discrepancies on combined designs, Metrika 74 (2011), pp. 109–119] for symmetric designs to asymmetric designs. Moreover, it also provides a theoretical justification for optimal foldover plans in terms of uniformity criterion.     

Minimal 2-coverings of a finite affine space based on GF(2)

Let EG(m, 2) denote the m-dimensional finite Euclidean space (or geometry) based on GF(2), the finite field with elements 0 and 1. Let T be a set of points in this space, then T is said to form a q-covering (where q is an integer satisfying 1?q?m) of EG(m, 2) if and only if T has a nonempty intersection with every (m-q)-flat of EG(m, 2). This problem first arose in the statistical context of factorial search designs where it is known to have very important and wide ranging applications. Evidently, it is also useful to study this from the purely combinatorial point of view. In this paper, certain fundamental studies have been made for the case when q=2. Let N denote the size of the set T. Given N, we study the maximal value of m.     

2<Superscript><Emphasis Type="Italic">m</Emphasis></Superscript>4<Superscript>1</Superscript> designs with minimum aberration or weak minimum aberration

For measuring the goodness of 2 ^m 4¹ designs, Wu and Zhang (1993) proposed the minimum aberration (MA) criterion. MA 2 ^m 4¹ designs have been constructed using the idea of complementary designs when the number of two-level factors, m, exceeds n/2, where n is the total number of runs. In this paper, the structures of MA 2 ^m 4¹ designs are obtained when m>5n/16. Based on these structures, some methods are developed for constructing MA 2 ^m 4¹ designs for 5n/16<m<n/2 as well as for n/2≤m<n. When m≤5n/16, there is no general method for constructing MA 2 ^m 4¹ designs. In this case, we obtain lower bounds for A ₃₀ and A ₃₁, where A ₃₀ and A ₃₁ are the numbers of type 0 and type 1 words with length three respectively. And a method for constructing weak minimum aberration (WMA) 2 ^m 4¹ designs (A ₃₀ and A ₃₁ achieving the lower bounds) is demonstrated. Some MA or WMA 2 ^m 4¹ designs with 32 or 64 runs are tabulated for practical use, which supplement the tables in Wu and Zhang (1993), Zhang and Shao (2001) and Mukerjee and Wu (2001).     

Hypercubic designs and applications

In this paper we develop relatively easy methods for constructing hypercubic designs from symmetrical factorial experiments for t=v ^m treatments with v=2, 3. The proposed methods are easy to use and are flexible in terms of choice of possible block sizes.     

Generating generalized cyclic designs with factorial balance

An algorithm for generating paired comparison factorially balanced generalized cyclic designs is described. The algorithm is based upon the 2 ⁿ ? 1 class association scheme defined by Shah (1960) for n-factor experiments. The algorithm is highly successful in achieving its objective. Firstorder designs with block size greater than two can also be obtained using the algorithm.