A bound for the Euclidean distance between restricted and unrestricted estimators of parametric functions in the general linear model

Let [^(\varveck)]{\widehat{\varvec{\kappa}}} and [^(\varveck)]_r{\widehat{\varvec{\kappa}}_r} denote the best linear unbiased estimators of a given vector of parametric functions \varveck = \varvecKb{\varvec{\kappa} = \varvec{K\beta}} in the general linear models M = {\varvecy, \varvecX\varvecb, s²\varvecV}{{\mathcal M} = \{\varvec{y},\, \varvec{X\varvec{\beta}},\, \sigma^2\varvec{V}\}} and M_r = {\varvecy, \varvecX\varvecb | \varvecR \varvecb = \varvecr, s²\varvecV}{{\mathcal M}_r = \{\varvec{y},\, \varvec{X}\varvec{\beta} \mid \varvec{R} \varvec{\beta} = \varvec{r},\, \sigma^2\varvec{V}\}}, respectively. A bound for the Euclidean distance between [^(\varveck)]{\widehat{\varvec{\kappa}}} and [^(\varveck)]_r{\widehat{\varvec{\kappa}}_r} is expressed by the spectral distance between the dispersion matrices of the two estimators, and the difference between sums of squared errors evaluated in the model M{{\mathcal M}} and sub-restricted model M_r^*{{\mathcal M}_r^*} containing an essential part of the restrictions \varvecR\varvecb = \varvecr{\varvec{R}\varvec{\beta} = \varvec{r}} with respect to estimating \varveck{\varvec{\kappa}}.     

Characterization of the mixtures of Rayleigh distributions by conditional expectation of order statistics

The mixture of Rayleigh random variables X ₁and X ₂ are identified in terms of relations between the conditional expectation of ( X_2:2² -X_1:2²)^r{\left( {X_{2:2}^2 -X_{1:2}^2}\right)^{r}} given X _1:2 (or X_2:2^2k{X_{2:2}^{2k}} given X_1:2,"k ￡ r){X_{1:2},\forall k\leq r)} and hazard rate function of the distribution, where X _1:2 and X _2:2 denote the corresponding order statistics, r is a positive integer. In addition, we also mention some related theorems to characterize the mixtures of Rayleigh distributions. Finally, we also give an application to Multi-Hit models of carcinogenesis (Parallel Systems) and a simulated example is used to illustrate our results.     

Quadratic subspaces and construction of Bayes invariant quadratic estimators of variance components in mixed linear models

Gnot et al. (J Statist Plann Inference 30(1):223–236, 1992) have presented the formulae for computing Bayes invariant quadratic estimators of variance components in normal mixed linear models of the form where the matrices V _i , 1 ≤ i ≤ k − 1, are symmetric and nonnegative definite and V _k is an identity matrix. These formulae involve a basis of a quadratic subspace containing MV ₁ M,...,MV _k-1 M,M, where M is an orthogonal projector on the null space of X′. In the paper we discuss methods of construction of such a basis. We survey Malley’s algorithms for finding the smallest quadratic subspace including a given set of symmetric matrices of the same order and propose some modifications of these algorithms. We also consider a class of matrices sharing some of the symmetries common to MV ₁ M,...,MV _k-1 M,M. We show that the matrices from this class constitute a quadratic subspace and describe its explicit basis, which can be directly used for computing Bayes invariant quadratic estimators of variance components. This basis can be also used for improving the efficiency of Malley’s algorithms when applied to finding a basis of the smallest quadratic subspace containing the matrices MV ₁ M,...,MV _k-1 M,M. Finally, we present the results of a numerical experiment which confirm the potential usefulness of the proposed methods. Dedicated to the memory of Professor Stanisław Gnot.     

Sequential experimental design and response optimisation

We consider the situation where one wants to maximise a functionf(θ,x) with respect tox, with θ unknown and estimated from observationsy _k . This may correspond to the case of a regression model, where one observesy _k =f(θ,x _k )+ε _k , with ε _k some random error, or to the Bernoulli case wherey _k ∈{0, 1}, with Pr[y _k =1|θ,x _k |=f(θ,x _k ). Special attention is given to sequences given by , with an estimated value of θ obtained from (x₁, y₁),...,(x _k ,y _k ) andd _k (x) a penalty for poor estimation. Approximately optimal rules are suggested in the linear regression case with a finite horizon, where one wants to maximize ∑ _i=1 ^N w _i f(θ, x _i ) with {w _i } a weighting sequence. Various examples are presented, with a comparison with a Polya urn design and an up-and-down method for a binary response problem.     

Comparison of location parameters of two exponential distributions when scale parameters are different and unknown

Letx _i(1)≤x _i(2)≤…≤x _i(r_i) be the right-censored samples of sizesn _i from theith exponential distributions $\sigma _i^{ - 1} exp\{ - (x - \mu _i )\sigma _i^{ - 1} \} ,i = 1,2$ where μ_i and σ_i are the unknown location and scale parameters respectively. This paper deals with the posteriori distribution of the difference between the two location parameters, namely μ₂-μ₁, which may be represented in the form $\mu _2 - \mu _1 \mathop = \limits^\mathcal{D} x_{2(1)} - x_{1(1)} + F_1 \sin \theta - F_2 \cos \theta $ where $\mathop = \limits^\mathcal{D} $ stands for equal in distribution,F _i stands for the central F-variable with [2,2(r _i?1)] degrees of freedom and $\tan \theta = \frac{{n_2 s_{x1} }}{{n_1 s_{x2} }}, s_{x1} = (r_1 - 1)^{ - 1} \left\{ {\sum\limits_{j = 1}^{r_i - 1} {(n_i - j)(x_{i(j + 1)} - x_{i(j)} )} } \right\}$ The paper also derives the distribution of the statisticV=F ₁ sin σ?F ₂ cos σ and tables of critical values of theV-statistic are provided for the 5% level of significance and selected degrees of freedom.     

Simultaneous marginal survival estimators when doubly censored data is present

A doubly censoring scheme occurs when the lifetimes T being measured, from a well-known time origin, are exactly observed within a window [L, R] of observational time and are otherwise censored either from above (right-censored observations) or below (left-censored observations). Sample data consists on the pairs (U, δ) where U = min{R, max{T, L}} and δ indicates whether T is exactly observed (δ = 0), right-censored (δ = 1) or left-censored (δ = −1). We are interested in the estimation of the marginal behaviour of the three random variables T, L and R based on the observed pairs (U, δ). We propose new nonparametric simultaneous marginal estimators [^(S)]_T, [^(S)]_L{\hat S_{T}, \hat S_{L}} and [^(S)]_R{\hat S_{R}} for the survival functions of T, L and R, respectively, by means of an inverse-probability-of-censoring approach. The proposed estimators [^(S)]_T, [^(S)]_L{\hat S_{T}, \hat S_{L}} and [^(S)]_R{\hat S_{R}} are not computationally intensive, generalize the empirical survival estimator and reduce to the Kaplan-Meier estimator in the absence of left-censored data. Furthermore, [^(S)]_T{\hat S_{T}} is equivalent to a self-consistent estimator, is uniformly strongly consistent and asymptotically normal. The method is illustrated with data from a cohort of drug users recruited in a detoxification program in Badalona (Spain). For these data we estimate the survival function for the elapsed time from starting IV-drugs to AIDS diagnosis, as well as the potential follow-up time. A simulation study is discussed to assess the performance of the three survival estimators for moderate sample sizes and different censoring levels.     

Biased estimation of a variance

Summary Let , whereX _i are i.i.d. random variables with a finite variance σ² and is the usual estimate of the mean ofX _i. We consider the problem of finding optimal α with respect to the minimization of the expected value of |S ²(σ)−σ²|^k for variousk and with respect to Pitman's nearness criterion. For the Gaussian case analytical results are obtained and for some non-Gaussian cases we present Monte Carlo results regarding Pitman's criteron. This research was supported by Science Fund of Serbia, grant number 04M03, through Mathematical Institute, Belgrade.     

Nonparametric comparison of curves with dependent errors

Suppose that data {(x _l,i,n , y _l,i,n ): l?=?1, …, k; i?=?1, …, n} are observed from the regression models: Y _l,i,n ?=?m _l (x _l,i,n )?+?? _l,i,n , l?=?1, …, k, where the regression functions {m _l } _l=1 ^k are unknown and the random errors {? _l,i,n } are dependent, following an MA(∞) structure. A new test is proposed for testing the hypothesis H ₀: m ₁?=?·?·?·?=?m _k , without assuming that {m _l } _l=1 ^k are in a parametric family. The criterion of the test derives from a Crámer-von-Mises-type functional based on different distances between {[mcirc]} _l and {[mcirc]} _s , l?≠?s, l, s?=?1, …, k, where {[mcirc] _l } _l=1 ^k are nonparametric Gasser–Müller estimators of {m _l } _l=1 ^k . A generalization of the test to the case of unequal design points, with different sample sizes {n _l } _l=1 ^k and different design densities {f _l } _l=1 ^k , is also considered. The asymptotic normality of the test statistic is obtained under general conditions. Finally, a simulation study and an analysis with real data show a good behavior of the proposed test.     

The type I distribution of the ratio of independent “Weibullized” generalized beta-prime variables

In this paper we introduce the distribution of , with c >  0, where X _i , i =  1, 2, are independent generalized beta-prime-distributed random variables, and establish a closed form expression of its density. This distribution has as its limiting case the generalized beta type I distribution recently introduced by Nadarajah and Kotz (2004). Due to the presence of several parameters the density can take a wide variety of shapes.      

On moments of the supremum of normed weighted averages

Let {X, X_n; n ≥ 1} be a sequence of real-valued iid random variables, 0 < r < 2 and p > 0. Let D = { A = (a_nk; 1 ≤ k ≤ n, n ≥ 1); a_nk, ? R and sup_{n, k} |a_n,k| < ∞}. Set S_n( A ) = ∑ⁿ_k=1a_{n, k}X_k for A ? D and n ≥ 1. This paper is devoted to determining conditions whereby E{sup_{n ≥ 1}, |S_n( A )|/n^1/r}^p < ∞ or E{sup_{n ≥ 2} |S_n( A )|/2n log n)^1/2}^p < ∞ for every A ? D. This generalizes some earlier results, including those of Burkholder (1962), Choi and Sung (1987), Davis (1971), Gut (1979), Klass (1974), Siegmund (1969) and Teicher (1971).     

Local asymptotic normality of intermediate and central order statistics

Consider n independent random variables Z_i,…, Z_n on R with common distribution function F, whose upper tail belongs to a parametric family F(t) = F_θ(t),t ≥ x₀, where θ ∈ ? ? R ^d. A necessary and sufficient condition for the family F_θ, θ ∈ ?, is established such that the k-th largest order statistic Z_n?k+1:n alone constitutes the central sequence yielding local asymptotic normality ( LAN ) of the loglikelihood ratio of the vector (Z_n?i+1:n)¹ _i=kof the k largest order statistics. This is achieved for k = k(n)→_n→∞∞ with k/n→_n→∞ 0.

In the case of vectors of central order statistics ( Z_r:n, Z_r+1:n,…, Z_s:n ), with r/n and s/n both converging to q ∈ ( 0,1 ), it turns out that under fairly general conditions any order statistic Z_m:n with r ≤ m ≤s builds the central sequence in a pertaining LAN expansion.These results lead to asymptotically optimal tests and estimators of the underlying parameter, which depend on single order statistics only     

Nonparametric Estimation of a Regression Function: Limiting Distribution2

Consider the regression model Y_i= g(x_i) + e_i, i = 1,…, n, where g is an unknown function defined on [0, 1], 0 = x₀ < x₁ < … < x_n≤ 1 are chosen so that max_1≤i≤n(x_i-x_{i- 1}) = 0(n^-1), and where {e_i} are i.i.d. with Ee₁= 0 and Var e₁ - s?². In a previous paper, Cheng & Lin (1979) study three estimators of g, namely, g_1n of Cheng & Lin (1979), g_2n of Clark (1977), and g_3n of Priestley & Chao (1972). Consistency results are established and rates of strong uniform convergence are obtained. In the current investigation the limiting distribution of &_in, i = 1, 2, 3, and that of the isotonic estimator g**_n are considered.     

Conditional estimation of average on the basis of weighting data

LetF(x,y) be a distribution function of a two dimensional random variable (X,Y). We assume that a distribution functionF _x(x) of the random variableX is known. The variableX will be called an auxiliary variable. Our purpose is estimation of the expected valuem=E(Y) on the basis of two-dimensional simple sample denoted by:U=[(X ₁, Y₁)…(X_n, Y_n)]=[X Y]. LetX=[X ₁…X _n]andY=[Y ₁…Y _n].This sample is drawn from a distribution determined by the functionF(x,y). LetX _(k)be the k-th (k=1, …,n) order statistic determined on the basis of the sampleX. The sampleU is truncated by means of this order statistic into two sub-samples: % MathType!End!2!1! and % MathType!End!2!1!.Let % MathType!End!2!1! and % MathType!End!2!1! be the sample means from the sub-samplesU _k,1 andU _k,2, respectively. The linear combination % MathType!End!2!1! of these means is the conditional estimator of the expected valuem. The coefficients of this linear combination depend on the distribution function of auxiliary variable in the pointx _(k).We can show that this statistic is conditionally as well as unconditionally unbiased estimator of the averagem. The variance of this estimator is derived. The variance of the statistic % MathType!End!2!1! is compared with the variance of the order sample mean. The generalization of the conditional estimation of the mean is considered, too.     

A Note on the Calculation of Pr{X 1 < X 2 < ··· < Xk }

Suppose that X_i are independent random variables, and that X_i has cdf F_i (x), 1 ≤ i ≤ k. Many statistical problems involve the probability Pr{X ₁ < X ₂ < ··· < X_k }. In this note a numerical method is proposed for computing this probability.     

A CHARACTERIZATION OF GEOMETRIC DISTRIBUTIONS THROUGH CONDITIONAL INDEPENDENCE

Let X₁,…, X_n be mutually independent non-negative integer-valued random variables with probability mass functions f_i(x) > 0 for z= 0,1,…. Let E denote the event that {X₁≥X₂≥…≥X_n}. This note shows that, conditional on the event E, X_i-X_i+ 1 and X_i+ 1 are independent for all t = 1,…, k if and only if X_i (i= 1,…, k) are geometric random variables, where 1 ≤k≤n-1. The k geometric distributions can have different parameters θ_i, i= 1,…, k.     

Comparing several exponential populations with more than one control

Suppose there are k ₁ (k ₁ ≥ 1) test treatments that we wish to compare with k ₂ (k ₂ ≥ 1) control treatments. Assume that the observations from the ith test treatment and the jth control treatment follow a two-parameter exponential distribution and , where θ is a common scale parameter and and are the location parameters of the ith test and the jth control treatment, respectively, i = 1, . . . ,k ₁; j = 1, . . . ,k ₂. In this paper, simultaneous one-sided and two-sided confidence intervals are proposed for all k ₁ k ₂ differences between the test treatment location and control treatment location parameters, namely , and the required critical points are provided. Discussions of multiple comparisons of all test treatments with the best control treatment and an optimal sample size allocation are given. Finally, it is shown that the critical points obtained can be used to construct simultaneous confidence intervals for Pareto distribution location parameters.     

Optimal spacing of the selected sample quantiles for the joint estimation of the location and scale parameters of a symmetric distribution

We are considering the ABLUE’s – asymptotic best linear unbiased estimators – of the location parameter μ and the scale parameter σ of the population jointly based on a set of selected k sample quantiles, when the population distribution has the density of the form

where the standardized function f(u) being of a known functional form.A set of selected sample quantiles with a designated spacing

or in terms of u=(x−μ)/σ

where

λ_i=∫_−∞^u_if(t) dt, i=1,2,…,k

are given by

x(n₁)<x(n₂)<<x(n_k),

where

Asymptotic distribution of the k sample quantiles when n is very large is given by

h(x(n₁),x(n₂),…,x(n_k);μ,σ)=(2πσ²)^−k/2[λ₁(λ₂−λ₁)(λ_k−λ_k−1)(1−λ_k)]^−1/2n^k/2 exp(−nS/2σ²),

where

f_i=f(u_i), i=0,1,…,k,k+1,

f₀=f_k+1=0, λ₀=0, λ_k+1=1.

The relative efficiency of the joint estimation is given by

where

and κ being independent of the spacing . The optimal spacing is the spacing which maximizes the relative efficiency η(μ,σ).We will prove the following rather remarkable theorem. Theorem. The optimal spacing for the joint estimation is symmetric, i.e.

λ_i+λ_k−i+1=1,

or

u_i+u_k−i+1=0, i=1,2,…,k,

if the standardized density f(u) of the population is differentiable infinitely many times and symmetric

f(−u)=f(u), f′(−u)=−f′(u).

     

Sequential Estimation of Expectations in the Presence of Trend2

A sequence of independent random variables {Z_n:n≥ 1} with unknown probability distributions is considered and the problem of estimating their expectations {M_n+1: n≥ 1} is examined. The estimation of M_n+1 is based on a finite set {z_k:1≤k≤n}, each z_k being an observed value of Z_k, 1 ≤k≤n, and also based on the assumption that {M_n:n≥ 1} follows an unknown trend of a specified form.     

Likelihood ratio inference for mean residual life

One of the basic parameters in survival analysis is the mean residual life M ₀. For right censored observation, the usual empirical likelihood based log-likelihood ratio leads to a scaled c₁²{\chi_1^2} limit distribution and estimating the scaled parameter leads to lower coverage of the corresponding confidence interval. To solve the problem, we present a log-likelihood ratio l(M ₀) by methods of Murphy and van der Vaart (Ann Stat 1471–1509, 1997). The limit distribution of l(M ₀) is the standard c₁²{\chi_1^2} distribution. Based on the limit distribution of l(M ₀), the corresponding confidence interval of M ₀ is constructed. Since the proof of the limit distribution does not offer a computational method for the maximization of the log-likelihood ratio, an EM algorithm is proposed. Simulation studies support the theoretical result.