Full likelihood inference in the Cox model with LTRC data when covariates are discrete

For the regression parameter β in the Cox model, there have been several estimates based on different types of approximated likelihood. For right-censored data, Ren and Zhou [Full likelihood inferences in the Cox model: an empirical approach. Ann Inst Statist Math. 2011;63:1005–1018] derive the full likelihood function for (β, F₀), where F₀ is the baseline distribution function in the Cox model. In this article, we extend their results to left-truncated and right-censored data with discrete covariates. Using the empirical likelihood parameterization, we obtain the full-profile likelihood function for β when covariates are discrete. Simulation results indicate that the maximum likelihood estimator outperforms Cox's partial likelihood estimator in finite samples.     

Optimal step-stress test under type I progressive group-censoring with random removals

Some traditional life tests result in no or very few failures by the end of test. In such cases, one approach is to do life testing at higher-than-usual stress conditions in order to obtain failures quickly. This paper discusses a k-level step-stress accelerated life test under type I progressive group-censoring with random removals. An exponential failure time distribution with mean life that is a log-linear function of stress and a cumulative exposure model are considered. We derive the maximum likelihood estimators of the model parameters and establish the asymptotic properties of the estimators. We investigate four selection criteria which enable us to obtain the optimum test plans. One is to minimize the asymptotic variance of the maximum likelihood estimator of the logarithm of the mean lifetime at use-condition, and the other three criteria are to maximize the determinant, trace and the smallest eigenvalue of Fisher's information matrix. Some numerical studies are discussed to illustrate the proposed criteria.     

On the Restricted Liu Estimator in the Logistic Regression Model

The logistic regression model is used when the response variables are dichotomous. In the presence of multicollinearity, the variance of the maximum likelihood estimator (MLE) becomes inflated. The Liu estimator for the linear regression model is proposed by Liu to remedy this problem. Urgan and Tez and Mansson et al. examined the Liu estimator (LE) for the logistic regression model. We introduced the restricted Liu estimator (RLE) for the logistic regression model. Moreover, a Monte Carlo simulation study is conducted for comparing the performances of the MLE, restricted maximum likelihood estimator (RMLE), LE, and RLE for the logistic regression model.     

Robust variance estimators for fixed-effect estimates with hierarchical-likelihood

In longitudinal studies, robust sandwich variance estimators are often used, and are especially useful when model assumptions are in doubt. However, the usual sandwich estimator does not allow for models with crossed random effects. The hierarchical likelihood extends the idea of the sandwich estimator to models not currently covered. By simulation studies, we show that the new sandwich estimator is robust against heteroscedastic errors and against misspecification of overdispersion in the y | v component.     

Bias Corrected Maximum Likelihood Estimator Under the Generalized Linear Model for a Binary Variable

Under the generalized linear models for a binary variable, an approximate bias of the maximum likelihood estimator of the coefficient, that is a special case of linear parameter in Cordeiro and McCullagh (1991), is derived without a calculation of the third-order derivative of the log likelihood function. Using the obtained approximate bias of the maximum likelihood estimator, a bias-corrected maximum likelihood estimator is defined. Through a simulation study, we show that the bias-corrected maximum likelihood estimator and its variance estimator have a better performance than the maximum likelihood estimator and its variance estimator.     

Semiparametric ARCH Models: An Estimating Function Approach

We introduce the method of estimating functions to study the class of autoregressive conditional heteroscedasticity (ARCH) models. We derive the optimal estimating functions by combining linear and quadratic estimating functions. The resultant estimators are more efficient than the quasi-maximum likelihood estimator. If the assumption of conditional normality is imposed, the estimator obtained by using the theory of estimating functions is identical to that obtained by using the maximum likelihood method in finite samples. The relative efficiencies of the estimating function (EF) approach in comparison with the quasi-maximum likelihood estimator are developed. We illustrate the EF approach using a univariate GARCH(1,1) model with conditional normal, Student-t, and gamma distributions. The efficiency benefits of the EF approach relative to the quasi-maximum likelihood approach are substantial for the gamma distribution with large skewness. Simulation analysis shows that the finite-sample properties of the estimators from the EF approach are attractive. EF estimators tend to display less bias and root mean squared error than the quasi-maximum likelihood estimator. The efficiency gains are substantial for highly nonnormal distributions. An example demonstrates that implementation of the method is straightforward.     

Clustering Discrete Data Through the Multinomial Mixture Model

In this work, the multinomial mixture model is studied, through a maximum likelihood approach. The convergence of the maximum likelihood estimator to a set with characteristics of interest is shown. A method to select the number of mixture components is developed based on the form of the maximum likelihood estimator. A simulation study is then carried out to verify its behavior. Finally, two applications on real data of multinomial mixtures are presented.     

Asymptotic cumulants of the minimum phi-divergence estimator for categorical data under possible model misspecification

Abstract

The asymptotic cumulants of the minimum phi-divergence estimators of the parameters in a model for categorical data are obtained up to the fourth order with the higher-order asymptotic variance under possible model misspecification. The corresponding asymptotic cumulants up to the third order for the studentized minimum phi-divergence estimator are also derived. These asymptotic cumulants, when a model is misspecified, depend on the form of the phi-divergence. Numerical illustrations with simulations are given for typical cases of the phi-divergence, where the maximum likelihood estimator does not necessarily give best results. Real data examples are shown using log-linear models for contingency tables.     

Confidence Intervals for the Current Status Model

We discuss a new way of constructing pointwise confidence intervals for the distribution function in the current status model. The confidence intervals are based on the smoothed maximum likelihood estimator, using local smooth functional theory and normal limit distributions. Bootstrap methods for constructing these intervals are considered. Other methods to construct confidence intervals, using the non‐standard limit distribution of the (restricted) maximum likelihood estimator, are compared with our approach via simulations and real data applications.     

Hellinger distance as a penalized log likelihood

The present paper studies the minimum Hellinger distance estimator by recasting it as the maximum likelihood estimator in a data driven modification of the model density. In the process, the Hellinger distance itself is expressed as a penalized log likelihood function. The penalty is the sum of the model probabilities over the non-observed values of the sample space. A comparison of the modified model density with the original data provides insights into the robustness of the minimum Hellinger distance estimator. Adjustments of the amount of penalty leads to a class of minimum penalized Hellinger distance estimators, some members of which perform substantially better than the minimum Hellinger distance estimator at the model for small samples, without compromising the robustness properties of the latter.     

Statistical Engineering

This article compares the accuracy of the median unbiased estimator with that of the maximum likelihood estimator for a logistic regression model with two binary covariates. The former estimator is shown to be uniformly more accurate than the latter for small to moderately large sample sizes and a broad range of parameter values. In view of the recently developed efficient algorithms for generating exact distributions of sufficient statistics in binary-data problems, these results call for a serious consideration of median unbiased estimation as an alternative to maximum likelihood estimation, especially when the sample size is not large, or when the data structure is sparse.     

Strong Consistency of the Maximum Likelihood Estimator for Finite Mixtures of Location–Scale Distributions When Penalty is Imposed on the Ratios of the Scale Parameters

Abstract.  In finite mixtures of location–scale distributions, if there is no constraint or penalty on the parameters, then the maximum likelihood estimator does not exist because the likelihood is unbounded. To avoid this problem, we consider a penalized likelihood, where the penalty is a function of the minimum of the ratios of the scale parameters and the sample size. It is shown that the penalized maximum likelihood estimator is strongly consistent. We also analyse the consistency of a penalized maximum likelihood estimator where the penalty is imposed on the scale parameters themselves.     

ASYMPTOTIC PROPERTIES OF RESTRICTED MAXIMUM LIKELIHOOD (REML) ESTIMATES FOR HIERARCHICAL MIXED LINEAR MODELS

This paper explores the asymptotic distribution of the restricted maximum likelihood estimator of the variance components in a general mixed model. Restricting attention to hierarchical models, central limit theorems are obtained using elementary arguments with only mild conditions on the covariates in the fixed part of the model and without having to assume that the data are either normally or spherically symmetrically distributed. Further, the REML and maximum likelihood estimators are shown to be asymptotically equivalent in this general framework, and the asymptotic distribution of the weighted least squares estimator (based on the REML estimator) of the fixed effect parameters is derived.     

Semiparametric ARCH Models

This article introduces a semiparametric autoregressive conditional heteroscedasticity (ARCH) model that has conditional first and second moments given by autoregressive moving average and ARCH parametric formulations but a conditional density that is assumed only to be sufficiently smooth to be approximated by a nonparametric density estimator. For several particular conditional densities, the relative efficiency of the quasi-maximum likelihood estimator is compared with maximum likelihood under correct specification. These potential efficiency gains for a fully adaptive procedure are compared in a Monte Carlo experiment with the observed gains from using the proposed semiparametric procedure, and it is found that the estimator captures a substantial proportion of the potential. The estimator is applied to daily stock returns from small firms that are found to exhibit conditional skewness and kurtosis and to the British pound to dollar exchange rate.     

Estimating survival curves with left truncated and interval censored data via the ems algorithm

It is well-known that the nonparametric maximum likelihood estimator (NPMLE) of a survival function may severely underestimate the survival probabilities at very early times for left truncated data. This problem might be overcome by instead computing a smoothed nonparametric estimator (SNE) via the EMS algorithm. The close connection between the SNE and the maximum penalized likelihood estimator is also established. Extensive Monte Carlo simulations demonstrate the superior performance of the SNE over that of the NPMLE, in terms of either bias or variance, even for moderately large Samples. The methodology is illustrated with an application to the Massachusetts Health Care Panel Study dataset to estimate the probability of being functionally independent for non-poor male and female groups rcspectively.     

Parameter estimation in a verhulst stochastic model

Summary Maximum likelihood estimation is a well-known statistical tool. When applied to the study of dynamical continuous-time phenomena, it requires some specific assumptions. In this paper we discuss some properties of the maximum likelihood estimator for a stochastic Verhulst model and we show some simulation results on the behaviour of the corresponding discrete estimator.     

Asymptotic properties of the ols and grls estimator for the replicated functional relationship model

For the simple linear functional relationship model with replication, the asymptotic properties of the ordinary (OLS) and grouping least squares (GRLS) estimator of the slope are investi- gated under the assumption of normally distributed errors with unknown covariance matrix. The relative performance of the OLS and GRLS estimator is compared in terms of the asymptotic mean square error, and a set of critical parameters are identified for determining the dominance of one estimator over the other. It is also shown that the GRLS estimator is asymptoticallyequivalent to the maximum likelihood (ML) estimator under the given assumptions.     

On Second Order Admissibilities in Two-Parameter Logistic Regression Model

In two-parameter family of distribution, conditions for a modified maximum likelihood estimator to be second-order admissible are given. Applying these results to two-parameter logistic regression model, it is shown that the maximum likelihood estimator is always second-order inadmissible and the Rao-Blackwellized minimum logit chi-squared estimator is second-order admissible if and only if the number of the doses is greater than or equal to 6.     

Nonparametric likelihood and doubly robust estimating equations for marginal and nested structural models

This article considers Robins's marginal and nested structural models in the cross‐sectional setting and develops likelihood and regression estimators. First, a nonparametric likelihood method is proposed by retaining a finite subset of all inherent and modelling constraints on the joint distributions of potential outcomes and covariates under a correctly specified propensity score model. A profile likelihood is derived by maximizing the nonparametric likelihood over these joint distributions subject to the retained constraints. The maximum likelihood estimator is intrinsically efficient based on the retained constraints and weakly locally efficient. Second, two regression estimators, named hat and tilde, are derived as first‐order approximations to the likelihood estimator under the propensity score model. The tilde regression estimator is intrinsically and weakly locally efficient and doubly robust. The methods are illustrated by data analysis for an observational study on right heart catheterization. The Canadian Journal of Statistics 38: 609–632; 2010 © 2010 Statistical Society of Canada     

Inference for proportional hazard model with propensity score

Since the publication of the seminal paper by Cox (1972), proportional hazard model has become very popular in regression analysis for right censored data. In observational studies, treatment assignment may depend on observed covariates. If these confounding variables are not accounted for properly, the inference based on the Cox proportional hazard model may perform poorly. As shown in Rosenbaum and Rubin (1983), under the strongly ignorable treatment assignment assumption, conditioning on the propensity score yields valid causal effect estimates. Therefore we incorporate the propensity score into the Cox model for causal inference with survival data. We derive the asymptotic property of the maximum partial likelihood estimator when the model is correctly specified. Simulation results show that our method performs quite well for observational data. The approach is applied to a real dataset on the time of readmission of trauma patients. We also derive the asymptotic property of the maximum partial likelihood estimator with a robust variance estimator, when the model is incorrectly specified.