Evaluation of a sequential global test of improved recovery following stroke as applied to the ICTUS trial of citicoline

The International Citicoline Trial in acUte Stroke is a sequential phase III study of the use of the drug citicoline in the treatment of acute ischaemic stroke, which was initiated in 2006 in 56 treatment centres. The primary objective of the trial is to demonstrate improved recovery of patients randomized to citicoline relative to those randomized to placebo after 12 weeks of follow-up. The primary analysis will take the form of a global test combining the dichotomized results of assessments on three well-established scales: the Barthel Index, the modified Rankin scale and the National Institutes of Health Stroke Scale. This approach was previously used in the analysis of the influential National Institute of Neurological Disorders and Stroke trial of recombinant tissue plasminogen activator in stroke.The purpose of this paper is to describe how this trial was designed, and in particular how the simultaneous objectives of taking into account three assessment scales, performing a series of interim analyses and conducting treatment allocation and adjusting the analyses to account for prognostic factors, including more than 50 treatment centres, were addressed.     

The importance of moral reflection and self-reported data in a dictator game with production

This article studies how individual behavior is affected by moral reflection in a dictator game with production. We make individuals reflect on fairness, in a structured way, before they play the dictator game. Our results suggest that moral reflection not only increases the weight people attach to fairness in distributive choices, but also has a strong effect on what people consider fair. Furthermore, we study the informational value of self-reported data. We find that self-reported data have substantial informational value, but do not add explanatory power to a random utility model estimated on purely behavioral data. Finally, we study whether there is a self-serving bias in the participants’ fairness perceptions, but do not find much evidence of this phenomenon in the data.     

HONG KONG FASHION DESIGNERS AS CULTURAL INTERMEDIARIES: OUT OF GLOBAL GARMENT PRODUCTION

This article offers a model for studying the dynamics of globalized popular musics, that fills methodological and theoretical lacunae in existing scholarly approaches. It deals with the emergence and circulation of a hybrid popular music called música ayacuchana, which over the 1990s became an important site of identification for the emergent Andean migrant middle class of Lima, Peru. Describing the role of radio stations and, particularly, DJs' actions in this process, I suggest that attention to the working practices of mediators can reveal how popular music becomes attached to new identities, particularly in the context of broader social changes. Further, I use this example to show why scholarly accounts of globalization, which rarely attend to the everyday mechanics of mediation, must take them into account, to arrive at a satisfactory understanding of the way that these processes engage, challenge, and/or reproduce social hierarchies.     

A secure base? The adolescent–staff relationship in secure residential youth care

The client–therapist relationship is recognized as an important factor contributing to outcomes of child and youth care. Particularly in secure residential youth care, in which adolescents with mainly externalizing behaviour problems are often placed coercively, the client–staff relationship seems to be important for the achievement of positive outcomes. The present study aims to assess the client–staff relationship for a group of 135 adolescents in secure residential care and factors associated with a positive relationship. The results show that adolescents, group care workers and teachers experience a limited affective bond in their relationship 2 months after the adolescents were admitted to the secure care centre. Adolescents do tend to use care workers and teachers as a secure attachment figure, which suggests that an affective bond is no precondition for the adolescents to experience staff as a secure base. Main predictors of a good relationship are the positive treatment skills of both group care workers and teachers. These findings point to the need for training of care workers and teachers so that they are better prepared for working with these adolescents.     

The Theory of Planned Behavior as it predicts potential intention to seek mental health services for depression among college students

ABSTRACT

Background: Between 9.5% and 31.3% of college students suffer from depression (American college health association national college health assessment II: reference group executive summary spring 2013. Amer. Coll. Health Assoc. 2013; Eagan K, Stolzenberg EB, Ramirez JJ, Aragon, MC, Suchard, RS, Hurtado S. The American freshman: national norms fall 2014. Higher Educ. Res. Inst.; 2015). Universities need to understand the factors that relate to care-seeking behavior. Objective: Across 3 studies, to relate attitudes, social norms, and perceived behavioral control to intention to seek mental health services, and to investigate barriers to care-seeking. Participants: University college students (N = 845, 64% female, 26% male, and 10% unspecified). Methods: New measures were created in Studies 1 and 2, and were examined using structural equation modeling in Study 3. Results: Partially consistent with the Theory of Planned Behavior (Ajzen, I, Fishbein, M. Understanding Attitudes and Predicting Social Behavior. Englewood Cliffs, NJ: Prentice-Hall; 1980), a model with an excellent fit revealed that more positive attitudes about care and higher perceived behavioral control directly predicted higher intention to seek mental health services. Conclusions: Educating college students about mental health disorders and treatments, enhancing knowledge about available services, and addressing limited access to long-term care might improve treatment rates for students suffering from depression.     

The Lovers of Venice: Musset’s Works and Life in Kuzmin’s A New Rolla

The title of Mikhail Kuzmin’s Novyi Rolla [A New Rolla] has been considered cryptic despite its evident allusion to Alfred de Musset’s “Rolla,” a poem with which it shares little. In this article I argue that the link to Musset is clear if we read A New Rolla as responding not just to “Rolla,” but also to Musset’s novel La Confession d’un enfant du siècle [The Confession of a Child of the Age] and his biography. From this composite source Kuzmin takes up the themes of a debauchee finding love, love as serial yet serious, and a love triangle in Venice, as well as an apostrophe to the kiss. Kuzmin endorses most of Musset’s idea of love, but rejects the egalitarian ideal implicit in the sympathetic treatment of the prostitute Marion in “Rolla.” A secondary allusion to Nikolai Nekrasov’s “Kogda iz mraka zabluzhden’ia” [When, out of the darkness of error] reinforces Kuzmin’s rejection of the egalitarian ideal of sexual love. The allusions to Musset and Nekrasov amount to anachronisms that partially undermine the precise temporal setting of A New Rolla. Kuzmin’s work thereby occupies an intermediate position among his period pieces, as it is neither openly playful like Venetsianskie bezumtsy [Venetian Madcaps] nor constructed with its seams hidden like the Aleksandriiskie pesni [Alexandrian Songs].     

The relationship between perceived employability and subsequent health

Abstract

Being capable of getting new employment may enable an employee to cope with turbulent situations or deteriorating job conditions. Individuals who have higher perceived employability are likely to appraise a situation at work more favourably, and consequently experience better health and well-being. The aim of the present study was to investigate the relationship between perceived employability and subsequent health, while controlling for baseline health, background factors, and work environment exposures. The study is based on 53 items in the National Working Life Cohort in Sweden from two data collections (2004 and 2005), comprising 1918 individuals. Forced entry hierarchical regression analysis showed that, after controlling for demographics, psychological demands, control, and ergonomic exposures, perceived employability was positively associated with global health and mental well-being, but unrelated to physical complaints. When baseline health status was added, perceived employability was still a significant predictor of two out of three outcome variables. Individuals with higher perceived employability had a tendency to report better health and well-being a year later. It is concluded that how an employee perceives his or her possibilities in regard to acquiring new employment is relevant for well-being at a later stage. Perceived employability, which has been little studied before, is therefore a useful concept in health promotion, both at the individual and at the organizational level.     

Dynamic capacity adjustments with reactive customers

In this paper we develop a behavioural model in which customers come and go based on their perception of waiting time (relative to other facilities) while managers gradually adjust the capacity of the facility based on their perception of demand. We explicitly account for the difference in access to information between existing and potential customers, which implies that the perception of potential customers lags the perception of current customers. We investigate the outcome of the interaction between these simultaneous dynamic decision processes, and in particular the impact of the lags created by the perception formation process and the time to implement desired changes in capacity. These multiple delays may result in customers and service provider being out of step: customers walk away just as the service provider manages to bring extra capacity online.