Coverage with k-transmitters in the presence of obstacles

For a fixed integer k≥0, a k-transmitter is an omnidirectional wireless transmitter with an infinite broadcast range that is able to penetrate up to k “walls”, represented as line segments in the plane. We develop lower and upper bounds for the number of k-transmitters that are necessary and sufficient to cover a given collection of line segments, polygonal chains and polygons.     

On the foundation and early development of domestic and international new ventures

The founding and early development of Domestic New Ventures and International New Ventures is examined based upon a large scale survey of Danish manufacturing firms. The firms are classified into five different categories and compared with regard to their foundation and development within the first 3?years. The article contributes with a demonstration of differences between these categories of firms with regard to the number and mindset of founders, the growth of the firm, and the networks of firm.     

Design Improvements for Message Propagation in Malleable Social Networks

This study presents the formal problem definition and computational analysis of the network design improvements for idea and message propagation in both enterprise and consumer social networks (ESN and CSN, respectively). Message propagation in social networks is impacted by how messages are seeded in the network, and by propagation characteristics of the network topology itself. It has been recognized that the propagation properties of these networks can be actively influenced by network design interventions, such as the deliberate creation of new connections. We address the problem of finding cost‐effective message seeding, and identifying potential new network connections that allow improved propagation in social networks with cascade propagation. We use the hop‐constrained minimum spanning tree (HMST) model to find the seeds and possible new connections that result in networks with improved propagation properties. Moreover, we present new heuristic algorithms that substantially improve the solution quality for the HMST problem. Computational results posit that the design improvements proposed by the HMST approach can greatly improve cascade propagation performance of the networks at low cost.     

Inference in disease transmission experiments by using stochastic epidemic models

Summary.  The paper extends the susceptible–exposed–infective–removed model to handle heterogeneity introduced by spatially arranged populations, biologically plausible distributional assumptions and incorporation of observations from additional diagnostic tests. These extensions are motivated by a desire to analyse disease transmission experiments in a more detailed fashion than before. Such experiments are performed by veterinarians to gain knowledge about the dynamics of an infectious disease. By fitting our spatial susceptible–exposed–infective–removed with diagnostic testing model to data for a specific disease and production environment a valuable decision support tool is obtained, e.g. when evaluating on-farm control measures. Partial observability of the epidemic process is an inherent problem when trying to estimate model parameters from experimental data. We therefore extend existing work on Markov chain Monte Carlo estimation in partially observable epidemics to the multitype epidemic set-up of our model. Throughout the paper, data from a Belgian classical swine fever virus transmission experiment are used as a motivating example.     

Designing Lives and Empowering Clients: The Case of Sue

This case response centers on the client Sue, a professional mediator who seeks counseling to resolve a conflict with her employer that threatens her vocational identity (M. C. Rehfuss, 2003). P. B. Baltes's (1997) Selective Optimization With Compensation model of human development and J. Heckhausen and R. Schulz's (1995) Life‐Span Theory of Control are used to frame Sue's career development, identify her current control orientation, and assist her in making the transition from compensation to an optimizing strategy. Such a strategy aims to preserve her vocational identity while satisfying the needs of her employer.     

Multilevel models for longitudinal variables prognostic for survival

The issue of modelling the joint distribution of survival time and of prognostic variables measured periodically has recently become of interest in the AIDS literature but is of relevance in other applications. The focus of this paper is on clinical trials where follow-up measurements of potentially prognostic variables are often collected but not routinely used. These measurements can be used to study the biological evolution of the disease of interest; in particular the effect of an active treatment can be examined by comparing the time profiles of patients in the active and placebo group. It is proposed to use multilevel regression analysis to model the individual repeated observations as function of time and, possibly, treatment. To address the problem of informative drop-out—which may arise if deaths (or any other censoring events) are related to the unobserved values of the prognostic variables—we analyse sequentially overlapping portions of the follow-up information. An example arising from a randomized clinical trial for the treatment of primary biliary cirrhosis is examined in detail.