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91.
There is considerable interest in assessing exposure to environmental tobacco smoke (ETS) and in understanding the factors that affect exposure at various venues. The impact of these complex factors can be researched only if monitoring studies are carefully designed. Prior work by Jenkins et al. gathered personal monitor and diary data from 1,564 nonsmokers in 16 metropolitan areas of the United States and compared workplace exposures to ETS with exposures away from work. In this study, these data were probed further to examine (1) the correspondence between work and away-from-work exposure concentrations of ETS; (2) the variability in exposure concentration levels across cities; and (3) the association of ETS exposure concentrations with select socioeconomic, occupation, and lifestyle variables. The results indicate (1) at the population level, there was a positive association between ETS concentrations at the work and away-from-work environments; (2) exposure concentration levels across the 16 cities under consideration were highly variable; and (3) exposure concentration levels were significantly associated with occupation, education, household income, age, and dietary factors. Workplace smoking restrictions were associated with low ETS concentration levels at work as well as away from work. Generally, the same cities that exhibited either lower or higher away-from-work exposure concentration levels also showed lower or higher work exposure concentration levels. The observations suggest that similar avoidance characteristics as well as socioeconomic and other lifestyle factors that affect exposure to ETS may have been in operation in both away-from-work and work settings.  相似文献   
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A semicompeting risks problem involves two-types of events: a nonterminal and a terminal event (death). Typically, the nonterminal event is the focus of the study, but the terminal event can preclude the occurrence of the nonterminal event. Semicompeting risks are ubiquitous in studies of aging. Examples of semicompeting risk dyads include: dementia and death, frailty syndrome and death, disability and death, and nursing home placement and death. Semicompeting risk models can be divided into two broad classes: models based only on observables quantities (class \(\mathcal {O}\) ) and those based on potential (latent) failure times (class \(\mathcal {L}\) ). The classical illness-death model belongs to class \(\mathcal {O}\) . This model is a special case of the multistate models, which has been an active area of methodology development. During the past decade and a half, there has also been a flurry of methodological activity on semicompeting risks based on latent failure times ( \(\mathcal {L}\) models). These advances notwithstanding, the semicompeting risks methodology has not penetrated biomedical research, in general, and gerontological research, in particular. Some possible reasons for this lack of uptake are: the methods are relatively new and sophisticated, conceptual problems associated with potential failure time models are difficult to overcome, paucity of expository articles aimed at educating practitioners, and non-availability of readily usable software. The main goals of this review article are: (i) to describe the major types of semicompeting risks problems arising in aging research, (ii) to provide a brief survey of the semicompeting risks methods, (iii) to suggest appropriate methods for addressing the problems in aging research, (iv) to highlight areas where more work is needed, and (v) to suggest ways to facilitate the uptake of the semicompeting risks methodology by the broader biomedical research community.  相似文献   
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A method is presented for selecting an a-level to use when testing for group difference in a one-way classification random effects model. The a-level is chosen to make the power of the test equal to .5 when the parameters are such that between group mean square and total mean square are equally good minimum expected squared error estimators of the variance of y the estimator of the mean  相似文献   
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Humans experience emotional benefits from engaging in prosocial behavior. The current work investigates factors that influence the experience of happiness from giving to others in early childhood. In three studies with 5-year-olds (N = 144), we find that young children are happier from giving resources to others than from receiving resources for themselves (Study 1) and investigate when children are most happy from giving. In Study 2, children were happier when they could see the beneficiary's positive reaction, suggesting that empathizing with the beneficiary's positive emotion contributes to happiness (consistent with the concept of vicarious-joy). In Study 3, children were happier after they gave resources than when they watched someone else give resources, indicating that being responsible for prosocial action contributes to children's happiness (consistent with the concept of warm-glow). These results provide a critical step toward understanding when children experience happiness from giving and a foundation for investigating happiness as a mechanism supporting early prosociality.  相似文献   
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