A Bayesian sequential design with binary outcome

Several researchers have proposed solutions to control type I error rate in sequential designs. The use of Bayesian sequential design becomes more common; however, these designs are subject to inflation of the type I error rate. We propose a Bayesian sequential design for binary outcome using an alpha‐spending function to control the overall type I error rate. Algorithms are presented for calculating critical values and power for the proposed designs. We also propose a new stopping rule for futility. Sensitivity analysis is implemented for assessing the effects of varying the parameters of the prior distribution and maximum total sample size on critical values. Alpha‐spending functions are compared using power and actual sample size through simulations. Further simulations show that, when total sample size is fixed, the proposed design has greater power than the traditional Bayesian sequential design, which sets equal stopping bounds at all interim analyses. We also find that the proposed design with the new stopping for futility rule results in greater power and can stop earlier with a smaller actual sample size, compared with the traditional stopping rule for futility when all other conditions are held constant. Finally, we apply the proposed method to a real data set and compare the results with traditional designs.     

Organizations as the building blocks of social inequalities

Most contemporary inequalities emerge in and are constituted through organizations. In this article, we review research at the intersection of organizations and inequalities, bringing the organizational literature and social stratification literature into conversation with one another. In doing so, we outline an emerging theoretical perspective, Relational Inequality Theory (RIT), that helps to make sense of how inequalities emerge within and between organizations. RIT places social relations within organizational contexts as constitutive of inequalities in access to organizational resources such as income, jobs, and respect. Much research supports theorizing inequalities as emerging through social relations within organizations, and we suggest comparative organizational designs as the key methodological strategy to study organizational inequalities.     

Academic Entrepreneurship: Time for a Rethink?

Academic entrepreneurship, which refers to efforts undertaken by universities to promote commercialization on campus and in surrounding regions of the university, has changed dramatically in recent years. Two key consequences of this change are that more stakeholders have become involved in academic entrepreneurship and that universities have become more ‘strategic’ in their approach to this activity. The authors assert that the time is ripe to rethink academic entrepreneurship. Specifically, theoretical and empirical research on academic entrepreneurship needs to take account of these changes, so as to improve the rigour and relevance of future studies on this topic. We outline such a framework and provide examples of key research questions that need to be addressed to broaden understanding of academic entrepreneurship.     

新奥尔良的发展:一部环境灾难史

2005年,卡特里娜和丽塔两大飓风侵袭路易斯安那州的新奥尔良市,成为美国历史上造成损失最大的灾难之一。这一貌似自然灾害的危害事件,其实孕育于新奥尔良的长期发展之中。一部新奥尔良发展史,既是人类利用土地、河流、森林、海洋等自然实体并与自然环境搏斗以建立城市、发展航运和工商业的历史,也是这些自然实体及其哺育的众多生命不断受侵蚀以至戕害的历史。这既是一部人类文明史,也是一部环境灾难史。在这里,人类借助水利工程控制自然而建立起来的文明,由于损害了生态系统的健康,削弱了其自然防护能力,结果反而加剧了人类无法避免的自然灾害的危害。因此,飓风造成的损失不只是取决于风暴之力,也取决于人们对土地的所作所为。而保持新奥尔良生机的努力,并不需要一味地与自然相搏,与自然合作,也是一种有益的尝试。     

A property of coefficients of variation for ordered bivariate log-normal variables

This paper considers the maximum and minimum of a pair of log-normal variables with equal mean. It shows that either order statistic has a smaller coefficient of variation than the two original log-normal variables provided the latter are of equal variance. When the variances are unequal, as the variance ratio increases, the minimum (maximum), has a smaller coefficient of variation if the correlation coefficient of the log-normal variables is small (small) and the variances are large (small).     

A Diamond-Stiglitz approach to the demand for self-protection

The existing research concerning the relationship between risk aversion and prudence and the demand for self-protection assumes that the loss variable follows a Bernoulli distribution, and that changes in the level of self-protection are mean preserving. The analysis here replaces these two very strong conditions with ones which are more general. When doing this, the method of analysis is also significantly modified. This modification includes representing a change in the level of self-protection using the procedure developed by Diamond and Stiglitz (Journal of Economic Theory 8:337-360, 1974) for representing a change in risk. This alternate representation allows the existing findings to be generalized considerably, and also simplifies the analysis.     

Relationship of interpersonal behaviors and health-related control appraisals to patient satisfaction and compliance in a university health center

OBJECTIVE: The authors' aim was to evaluate patient-provider relationships in a college health center. PARTICIPANTS: Eighty student patients and their health-care providers. METHODS: Patients completed a measure of perceived health competence before a consultation and measures of provider participatory behavior and interpersonal behavior before and after the consultation. They evaluated their satisfaction with care and compliance after the consultation and again 2 weeks later. Providers completed measures of their participatory behavior and patients' interpersonal behavior after the consultation. RESULTS: Patients preferred to be well informed and to have their preferences taken into account, and generally felt competent at managing their own health affairs. They indicated they obtained the high level of participation they desired. Patients desired and actually experienced friendly and submissive providers. Degree of match between patients' desired and actual level of involvement in their care was associated with greater satisfaction. A greater match between the extent to which they desired the provider to be affiliative and the provider's actual affiliative behavior was associated with more satisfaction. No variables were predictive of patient compliance. CONCLUSION: The authors discuss results in terms of the influence of situational factors characteristic of a college health center.     

The self-perceptions and interpersonal relationships of persons with significant physical disabilities: a qualitative pilot study

This exploratory, qualitative research was conducted to obtain the perspectives of people with significant physical disabilities regarding factors that have facilitated and hindered the development of a positive self-concept, participation in the broader society, and the formation of interpersonal relationships. The sample was high achieving in terms of education and/or career and attributed positive self-perceptions and their success in the broader society and interpersonal relationships to the attitudes and perceptions regarding their abilities, talents, and potential modeled in supportive family relationships. Females reported the influence of significant others most often, and males the effectiveness of their personality characteristics. Societal barriers, both practical and attitudinal, were reported along with the process for developing a positive selfperception despite these.     

An Evaluation of Stimulus Preference Assessment Methodology in Organizational Behavior Management

The organizational behavior management literature has yielded few stimulus preference assessment methodologies for use with employees. The current investigation compared three preference assessments (ranking, survey, and multiple stimulus without replacement procedures) found in the organizational behavior management literature for their ability to predict reinforcers for direct care staff members’ behavior. In the first experiment all assessments were effective for predicting reinforcers, but the results were limited by a lack of control items in the assessment. In the second experiment the survey and ranking assessments both proved to be effective for identifying reinforcers and neutral or ineffective stimuli. Implications of these results and directions for future research are discussed.