Parametric Estimation of Menarcheal Age Distribution Based on Recall Data

Menarche, the onset of menstruation, is an important maturational event of female childhood. Most of the studies of age at menarche make use of dichotomous (status quo) data. More information can be harnessed from recall data, but such data are often censored in a informative way. We show that the usual maximum likelihood estimator based on interval censored data, which ignores the informative nature of censoring, can be biased and inconsistent. We propose a parametric estimator of the menarcheal age distribution on the basis of a realistic model of the recall phenomenon. We identify the additional information contained in the recall data and demonstrate theoretically as well as through simulations the advantage of the maximum likelihood estimator based on recall data over that based on status quo data.     

Optimum mixture designs in a restricted region

In a mixture experiment, the response depends on the proportions of the mixing components. Canonical models of different degrees and also other models have been suggested to represent the mean response. Optimum designs for estimation of the parameters of the models have been investigated by different authors. In most cases, the optimum design includes the vertex points of the simplex as support points of the design, which are not mixture combinations in the true non-trivial sense. In this paper, optimum designs have been obtained when the experimental region is an ellipsoidal subspace of the entire factor space which does not cover the vertex points of the simplex.     

美德伦理学和正确的行动

最近一些著名的美德伦理学家试图对正确的行动提出种种美德伦理学所独有的解释。文章打算证明这些解释并不成功。如果它们能够回答岛民诘难 (根据这一诘难 ,评价行动要求注意行动者之外的外部世界的效果 ,然而美德伦理学只关心评价行动者的内在状态 ) ,它们依赖的是某些普遍接受的美德伦理学的理由 ,而这些理由本身又取决于没有任何解释的关于正确性的判断。因此这样的解释导致了循环论证的诘难。简言之 ,美德伦理学的这些避免岛民诘难的解释只是以请进循环论证的诘难为代价的。它们直觉上的合理性大致上只达到这样的程度 :它们失去了有别于其他理论的美德伦理学的特征     

Designs Robust against Violation of Normality Assumption in the Standard F-test

In this article, designs are found for which the F-test of analysis of variance is insensitive to violation of normality assumption. Atiqullah (1962 Atiquallah, M. (1962). The estimation of residual variance in quadratically balanced least-squares problems and the robustness of the F-test. Biometrika 49: 83–91.[Crossref], [Web of Science ®] , [Google Scholar]) proved that the F-test for treatments adjusting for blocks in the intra-block analysis of a balanced incomplete block design is robust against non-normality in the observations. Here an attempt has been made to identify other designs robust in this sense. In particular, it is observed that for testing relevant hypothesis, a partially balanced incomplete block design in block design setup, under certain conditions, is robust. Robustness of a balanced treatment incomplete block design and a partially balanced treatment incomplete block design (Biswas, 2012 Biswas, A. (2012). Block designs robust against the presence of an aberration in a treatment-control setup. Commun Statist.Theor Methods 41: 920–933.[Taylor & Francis Online], [Web of Science ®] , [Google Scholar]), in treatment-control design setup, is also studied. Moreover, a new measure of robustness is introduced for further study. The performance of the F-test in presence of non-normality in the observations for a quadratically balanced design is also examined.     

Inference from the Exponentiated Weibull Model with Applications to Real Data

In this paper, a novel Bayesian framework is used to derive the posterior density function, predictive density for a single future response, a bivariate future response, and several future responses from the exponentiated Weibull model (EWM). We study three related types of models, the exponentiated exponential, exponentiated Weibull, and beta generalized exponential, which are all utilized to determine the goodness of fit of two real data sets. The statistical analysis indicates that the EWM best fits both data sets. We determine the predictive means, standard deviations, highest predictive density intervals, and the shape characteristics for a single future response. We also consider a new parameterization method to determine the posterior kernel densities for the parameters. The summary results of the parameters are calculated by using the Markov chain Monte Carlo method.     

Analysing exponential family based messy data

Recently exponential family based random effects models have received considerable attention. These models usually arise from an unobservable random process added to the independent exponential family models. An unobservable correlated process, however, would cause correlations among the exponential family based data. This paper, first, develops an asymptotically optimal test for testing the appropriateness of a fixed effects model for the exponential family based independent data versus a random effects model for the exponential family based independent or correlated data. The paper, then, provides a general framework on regression analysis for the exponential family based data generated under the random effects models.     

Corrected profile likelihood confidence interval for binomial paired incomplete data

Clinical trials often use paired binomial data as their clinical endpoint. The confidence interval is frequently used to estimate the treatment performance. Tang et al. (2009) have proposed exact and approximate unconditional methods for constructing a confidence interval in the presence of incomplete paired binary data. The approach proposed by Tang et al. can be overly conservative with large expected confidence interval width (ECIW) in some situations. We propose a profile likelihood‐based method with a Jeffreys' prior correction to construct the confidence interval. This approach generates confidence interval with a much better coverage probability and shorter ECIWs. The performances of the method along with the corrections are demonstrated through extensive simulation. Finally, three real world data sets are analyzed by all the methods. Statistical Analysis System (SAS) codes to execute the profile likelihood‐based methods are also presented. Copyright © 2013 John Wiley & Sons, Ltd.     

Robust inference for generalized partially linear mixed models that account for censored responses and missing covariates – an application to Arctic data analysis

In this article, we propose a family of bounded influence robust estimates for the parametric and non-parametric components of a generalized partially linear mixed model that are subject to censored responses and missing covariates. The asymptotic properties of the proposed estimates have been looked into. The estimates are obtained by using Monte Carlo expectation–maximization algorithm. An approximate method which reduces the computational time to a great extent is also proposed. A simulation study shows that performances of the two approaches are similar in terms of bias and mean square error. The analysis is illustrated through a study on the effect of environmental factors on the phytoplankton cell count.     

D-Optimal Designs for Covariate Models

The problem of finding D-optimal designs in the presence of a number of covariates has been considered in the one-way set-up. This is an extension of Dey and Mukerjee (2006 Dey , A. , Mukerjee , R. ( 2006 ). D-optimal designs for covariate models . Statistics 40 : 297 – 305 .[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) in the sense that for fixed replication numbers of each treatment, an alternative upper bound to the determinant of the information matrix has been found through completely symmetric C-matrices for the regression coefficients; this upper bound includes the upper bound given in Dey and Mukerjee (2006 Dey , A. , Mukerjee , R. ( 2006 ). D-optimal designs for covariate models . Statistics 40 : 297 – 305 .[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) obtained through diagonal C-matrices. Because of the fact that a smaller class of C-matrices was used at the intermediate stage where the replication numbers were fixed, ultimately some optimal designs remained unidentified there. These designs have been identified here and thereby the conjecture made in Dey and Mukerjee (2006 Dey , A. , Mukerjee , R. ( 2006 ). D-optimal designs for covariate models . Statistics 40 : 297 – 305 .[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) has been settled.