Life satisfaction in China and consumption and income inequalities

This research uses nationally representative data to study how economic resources and inequalities are associated with life satisfaction of Chinese residents. We construct economic resource and inequality measures from expenditure rather than from income, after confirming that expenditure inequality is a better measure in the Chinese context. We find that economic inequalities in general are negatively associated with life satisfaction, and that this association is larger for inequalities in the lower half of the distribution than those in the upper half of the distribution. We further explore the mechanisms under which inequality can be associated with life satisfaction, and find that aspiration is potentially one important channel.     

Development of predictive signatures for treatment selection in precision medicine with survival outcomes

For survival endpoints in subgroup selection, a score conversion model is often used to convert the set of biomarkers for each patient into a univariate score and using the median of the univariate scores to divide the patients into biomarker‐positive and biomarker‐negative subgroups. However, this may lead to bias in patient subgroup identification regarding the 2 issues: (1) treatment is equally effective for all patients and/or there is no subgroup difference; (2) the median value of the univariate scores as a cutoff may be inappropriate if the sizes of the 2 subgroups are differ substantially. We utilize a univariate composite score method to convert the set of patient's candidate biomarkers to a univariate response score. We propose applying the likelihood ratio test (LRT) to assess homogeneity of the sampled patients to address the first issue. In the context of identification of the subgroup of responders in adaptive design to demonstrate improvement of treatment efficacy (adaptive power), we suggest that subgroup selection is carried out if the LRT is significant. For the second issue, we utilize a likelihood‐based change‐point algorithm to find an optimal cutoff. Our simulation study shows that type I error generally is controlled, while the overall adaptive power to detect treatment effects sacrifices approximately 4.5% for the simulation designs considered by performing the LRT; furthermore, the change‐point algorithm outperforms the median cutoff considerably when the subgroup sizes differ substantially.     

Response‐adaptive designs for binary responses: How to offer patient benefit while being robust to time trends?

Response‐adaptive randomisation (RAR) can considerably improve the chances of a successful treatment outcome for patients in a clinical trial by skewing the allocation probability towards better performing treatments as data accumulates. There is considerable interest in using RAR designs in drug development for rare diseases, where traditional designs are not either feasible or ethically questionable. In this paper, we discuss and address a major criticism levelled at RAR: namely, type I error inflation due to an unknown time trend over the course of the trial. The most common cause of this phenomenon is changes in the characteristics of recruited patients—referred to as patient drift. This is a realistic concern for clinical trials in rare diseases due to their lengthly accrual rate. We compute the type I error inflation as a function of the time trend magnitude to determine in which contexts the problem is most exacerbated. We then assess the ability of different correction methods to preserve type I error in these contexts and their performance in terms of other operating characteristics, including patient benefit and power. We make recommendations as to which correction methods are most suitable in the rare disease context for several RAR rules, differentiating between the 2‐armed and the multi‐armed case. We further propose a RAR design for multi‐armed clinical trials, which is computationally efficient and robust to several time trends considered.     

Coercive controlling behaviors in intimate partner violence in male same-sex relationships:A mixed-methods study

Using mixed methods, we explored the role of coercive controlling behaviors in a high-risk sample of 126 men in violent same-sex relationships. Contrary to a prediction that separate factors of physical violence and coercive control might emerge, a simple principle components analysis supported that male same-sex relationship intimate partner violence (IPV) is essentially unidimensional. Qualitative narratives supported a single latent factor solution of violence, and that coercive controlling behaviors better detect IPV dynamics within the same violent encounters (i.e., weapon use), even when compared to profiles defined by physical violence. Narratives also highlighted gender-different tactics of coercion used, underscoring importance of context-based assessments.     

Teaching Children With Autism Spectrum Disorder to Report Past Behavior With the Use of a Speech-Generating Device

The Analysis of Verbal Behavior -     

Relationship of bird richness,abundance and assemblage to the built environment in a small island tropical urban setting: a Suva,Fiji case study

There have been few studies investigating the relationship between the built environment and the status of bird distributions in small island tropical urban areas. We present a study investigating the relationship between bird species richness, abundance and assemblage to the built environment in Suva, Fiji. Field surveys were taken at 54 randomly selected sites throughout the city, stratified by three building density classes and the central business district (CBD). At each site bird counts were recorded, along with environmental data such as average building height, within a 150 m radius. Land-use information was obtained from screen digitized high-resolution satellite imagery within the same radius. Distance to undeveloped patches of land within the urban area was calculated using a GIS. Analysis of the effects of the built environment was carried out for all species, and for exotic and native species separately. Abundance of exotics was significantly higher in the central business district (CBD) than all other urban density classes, and significantly higher than natives in all other density classes. We found a negative relationship between native species richness and distance to undeveloped patches, but no relationship for exotics. Species assemblage was not related to urban density class. We conclude that the status of native and exotic bird species in Suva is similar to what has been found in urban areas in temperate climates, and conservation efforts should focus on minimizing the amount of heavily urbanized “core areas” and protecting undeveloped areas of forested vegetation to improve bird biodiversity in small tropical islands cities.

     

Using a Person-Centered Approach to Examine the Impact of Homelessness on School Absences

Brought on by increasing levels of economic vulnerability, homelessness is a pressing issue for our schools. Homeless students often miss an inordinate amount of school days and are thought to fall at the farthest end of a “continuum of poverty.” Theoretically they have worse outcomes than their peers, though the past 20 years of literature have found inconsistencies in these comparisons. Thus the literature suggests analysis to compare types of students based on outcomes rather than demographic categorizations, a person-centered approach. Using this approach, a comparison of the number of absences for homeless students and their housed peers is made through quantile analysis. Using school administrative data collected over one school year for an entire school district we found that homeless students as an aggregate do not miss significantly more days of school than their poorest peers. However, we found homelessness and poverty dramatically increase the number of absences for children who are in the higher percentiles of absences meaning homelessness has a greater impact on those who miss more days of school in general compared to regular attendees. Findings from this study indicate that homelessness may exacerbate problems rather than cause them. Implications for practice are discussed and directions for future study are proposed.