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61.
The stalactite plot for the detection of multivariate outliers   总被引:1,自引:0,他引:1  
Detection of multiple outliers in multivariate data using Mahalanobis distances requires robust estimates of the means and covariance of the data. We obtain this by sequential construction of an outlier free subset of the data, starting from a small random subset. The stalactite plot provides a cogent summary of suspected outliers as the subset size increases. The dependence on subset size can be virtually removed by a simulation-based normalization. Combined with probability plots and resampling procedures, the stalactite plot, particularly in its normalized form, leads to identification of multivariate outliers, even in the presence of appreciable masking.  相似文献   
62.
This paper argues that the existing sociological literature on the learned professions and on scientific occupations has developed in ways that are now theoretically unproductive. One sympton of this dead-end is the failure of sociologists of the professions to include research on scientists in their discussions and vice versa. A second symptom is the lack of attention to the implications of the work of Jamous, Peloille. and Bourdieu in both the sociology of scientists and of professions. The third symptom of the malaise is the failure to generate sociologically plausible explanations for the marginalisation of female entrants to science and the professions. The paper argues that a novel direction for sociological argument can be derived by remedying the three symptoms simultaneously.  相似文献   
63.
In May 2012, the Committee of Health and Medicinal Products issued a concept paper on the need to review the points to consider document on multiplicity issues in clinical trials. In preparation for the release of the updated guidance document, Statisticians in the Pharmaceutical Industry held a one‐day expert group meeting in January 2013. Topics debated included multiplicity and the drug development process, the usefulness and limitations of newly developed strategies to deal with multiplicity, multiplicity issues arising from interim decisions and multiregional development, and the need for simultaneous confidence intervals (CIs) corresponding to multiple test procedures. A clear message from the meeting was that multiplicity adjustments need to be considered when the intention is to make a formal statement about efficacy or safety based on hypothesis tests. Statisticians have a key role when designing studies to assess what adjustment really means in the context of the research being conducted. More thought during the planning phase needs to be given to multiplicity adjustments for secondary endpoints given these are increasing in importance in differentiating products in the market place. No consensus was reached on the role of simultaneous CIs in the context of superiority trials. It was argued that unadjusted intervals should be employed as the primary purpose of the intervals is estimation, while the purpose of hypothesis testing is to formally establish an effect. The opposing view was that CIs should correspond to the test decision whenever possible. Copyright © 2013 John Wiley & Sons, Ltd.  相似文献   
64.
As the Chinese government has purposefully built economic, social and political links with several African states in recent decades, new patterns of international migration have emerged. Notably, mixed‐race families are increasingly visible in southern China, particularly Guangzhou, where there is a concentration of African traders. The few existing studies on this population have failed to pay attention to how, in the absence of state provision of or support for key public resources including health care and education, African‐Chinese families are raising their children. We examined factors contributing to NGO successes and failures in facilitating these families’ wellbeing and integration into mainstream society, drawing on the theory of voluntary sector failure. Mixed‐raced families are relatively isolated from mainstream society as well as formal/informal civil society organisations. We found select features of philanthropic paternalism, philanthropic amateurism, and what we term philanthropic mistrust, with implications for understanding voluntary sector growth in the Chinese context.  相似文献   
65.
We construct a mathematical model of aerosol (i.e., droplet-nuclei) transmission of influenza within a household containing one infected and embed it into an epidemic households model in which infecteds occasionally infect someone from another household; in a companion paper, we argue that the contribution from contact transmission is trivial for influenza and the contribution from droplet transmission is likely to be small. Our model predicts that the key infection control measure is the use of N95 respirators, and that the combination of respirators, humidifiers, and ventilation reduces the threshold parameter (which dictates whether or not an epidemic breaks out) by ≈20% if 70% of households comply, and by ≈40% if 70% of households and workplaces comply (≈28% reduction would have been required to control the 1918 pandemic). However, only ≈30% of the benefits in the household are achieved if these interventions are used only after the infected develops symptoms. It is also important for people to sleep in separate bedrooms throughout the pandemic, space permitting. Surgical masks with a device (e.g., nylon hosiery) to reduce face-seal leakage are a reasonable alternative to N95 respirators if the latter are in short supply.  相似文献   
66.
Donor conception and parent–child relationships were explored from the child's perspective. At ages 7 and 10, interview data were obtained from children in 31 donor insemination, 28 egg donation and 51 natural conception families. Children were also administered the MacArthur Story Stem Battery and a family map. Children in all family types reported close and affectionate relationships with their parents, irrespective of the lack of a genetic link between the parent and the child. Of those children who were aware of their donor conception at age 10, most demonstrated an understanding of, and had positive feelings about their donor conception.  相似文献   
67.
The conception of a product is closely tied to its adaptation level to the users. In this view, designers are increasingly oriented to survey the needs and features of the users. This paper aims at developing a diagnosis of employees working in high-complexity activities in a petrochemical company, in light of the physical and operating changes in the Integrated Center of Control; assessing the reception sensibility to changes; assessing the cognitive pattern of the group; and making suggestions that might eliminate or minimize the difficulties in the transition process of the change, in order to reduce the adaptation period. The field of study comprised 111 production, transfer and storage operators, forming 5 groups of desktop activities. The stages of the study followed the following flow: survey of the prescribed tasks and organizational structure; Concentrated Attention test; application of the Work and Disease Risks Inventory (ITRA, Portuguese acronym); and structured psychological interview. The ITRA results pointed to a serious cognitive cost (3.83) for all five groups, this being the largest intervention focus. The items: division of task contents (3.52), social professional relationships (2.93), quality of the physical environment (2.91), physical cost (3.24), emotional cost (2.71), freedom of expression (3.77), professional fulfillment (3.41); experience and suffering (2.75), lack of recognition (2.18) and physical injuries (2.07) were considered critical. Meanwhile, social damages (1.64) and psychological injuries (1.35) are bearable. As to the Concentrated Attention test, most workers registered average level. In the individual interviews, workers showed that larger involvement in the process of physical, organizational and operational change in the desktops and on field works was required, as well as the follow up of implementations, so as to reduce the adaptation process and prevent rework (furniture, equipment, noise, form of communication with the area and training for the changes). As a result of the findings handed to the management and returned to the workers, several actions were implemented on ergonomic non-conformities found in the analysis. It is possible to prove the importance of the insertion of cognitive and organizational ergonomics in the building projects of new facilities for high-complexity activities in petrochemical plants.  相似文献   
68.
69.
There is relatively little research on the communication skills that social workers use in direct practice with families. This study explores patterns of practice skill found in child and family social work home visits. The study analysed 127 practice interactions in family homes, coding for seven dimensions of worker skill using a coding framework drawn from motivational interviewing. Exploratory factor analysis was employed to establish patterns of skill within the data and to group key dimensions of skill. The findings make two contributions. First, three fundamental dimensions of good practice emerged, which we characterize as care and engagement, good authority, and support for behaviour change. Second, in exploring the relationship between “care” and “control” elements of social work, skilled social workers were able to combine good authority and empathic engagement, whereas those who were less skilled in use of authority were also less good at engagement. This contributes to debates about care and control in social work. The usefulness of these dimensions for conceptualizing practice in child and family social work is discussed and directions for further research are suggested.  相似文献   
70.
Public Organization Review - The objective of the (U.S.) Federal Aviation Administration Airport Improvement Program (AIP) is “to help in developing a nationwide system of public-use airports...  相似文献   
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