Bayesian structural equation modeling for the health index

There are many factors which could influence the level of health of an individual. These factors are interactive and their overall effects on health are usually measured by an index which is called as health index. The health index could also be used as an indicator to describe the health level of a community. Since the health index is important, many research have been done to study its determinant. The main purpose of this study is to model the health index of an individual based on classical structural equation modeling (SEM) and Bayesian SEM. For estimation of the parameters in the measurement and structural equation models, the classical SEM applies the robust-weighted least-square approach, while the Bayesian SEM implements the Gibbs sampler algorithm. The Bayesian SEM approach allows the user to use the prior information for updating the current information on the parameter. Both methods are applied to the data gathered from a survey conducted in Hulu Langat, a district in Malaysia. Based on the classical and the Bayesian SEM, it is found that demographic status and lifestyle are significantly related to the health index. However, mental health has no significant relation to the health index.     

Multiscale Adaptive Regression Models for Neuroimaging Data

Neuroimaging studies aim to analyze imaging data with complex spatial patterns in a large number of locations (called voxels) on a two-dimensional (2D) surface or in a 3D volume. Conventional analyses of imaging data include two sequential steps: spatially smoothing imaging data and then independently fitting a statistical model at each voxel. However, conventional analyses suffer from the same amount of smoothing throughout the whole image, the arbitrary choice of smoothing extent, and low statistical power in detecting spatial patterns. We propose a multiscale adaptive regression model (MARM) to integrate the propagation-separation (PS) approach (Polzehl and Spokoiny, 2000, 2006) with statistical modeling at each voxel for spatial and adaptive analysis of neuroimaging data from multiple subjects. MARM has three features: being spatial, being hierarchical, and being adaptive. We use a multiscale adaptive estimation and testing procedure (MAET) to utilize imaging observations from the neighboring voxels of the current voxel to adaptively calculate parameter estimates and test statistics. Theoretically, we establish consistency and asymptotic normality of the adaptive parameter estimates and the asymptotic distribution of the adaptive test statistics. Our simulation studies and real data analysis confirm that MARM significantly outperforms conventional analyses of imaging data.