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71.
We present efficient algorithms for local alignment search in biological sequences. These algorithms identify maximal segment pairs (MSPs). Our algorithms have the potential of performing better than BLAST (Basic Local Alignment Search Tool) and also are efficiently parallelizable. We employ Fast Fourier Transforms (FFTs). Though several attempts have been made in the past to employ FFTs in sequence analysis, they fail to capture local similarities. Our algorithms employ FFTs in a novel way to identify local similarities. FFT-based techniques have the attractive feature of benefiting from ultrafast special purpose hardware available for digital signal processing.  相似文献   
72.
A large literature provides strong empirical support for the influence of parenting on child outcomes. The current study addresses enduring research questions testing the importance of early parenting behavior to children's adjustment. Specifically, we developed and tested a novel multi‐method observational measure of parental positive behavior support at age 2. Next, we tested whether early parental positive behavior support was related to child adjustment at school age, within a multi‐agent and multi‐method measurement approach and design. Observational and parent‐reported data from mother–child dyads (N = 731; 49 percent female) were collected from a high‐risk sample at age 2. Follow‐up data were collected via teacher report and child assessment at age 7.5. The results supported combining three different observational methods to assess positive behavior support at age 2 within a latent factor. Further, parents' observed positive behavior support at age 2 predicted multiple types of teacher‐reported and child‐assessed problem behavior and competencies at 7.5 years old. Results supported the validity and predictive capability of a multi‐method observational measure of parenting and the importance of a continued focus on the early years within preventive interventions.  相似文献   
73.
Objective: Suicide remains a pressing issue for college communities. Consequently, gatekeeper trainings are often provided for staff. This study examines the effect of one such program, Applied Suicide Intervention Skills Training (ASIST). Participants: 51 college employees received ASIST in August of 2014 and were compared to 30 wait-list control participants. Methods: Repeated Measures ANOVA were used to analyze pre- and post-training: (a) skills at responding to students-at-risk; (b) attitudes toward suicide; (c) knowledge about suicide; and (d) comfort/competence/confidence at helping a student-at-risk. Results: Significant positive training effects were observed for ASIST on self-report measures and also for objectively assessed skill at responding, after adjusting for a potential scoring limitation of the Suicide Intervention Response Inventory, Revised (SIRI-2). Conclusions: ASIST improved the self-perception of college staff at working with students-at-risk of suicide and also their skills at performing an intervention. Further, analysis of SIRI-2 data provides support for a potential instrument revision.  相似文献   
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This paper assesses the potential of mark-recapture methods as a relatively powerful innovative research method for estimating the prevalence of "hard-to-reach"human populations in the social welfare field. We outline the development of mark-recapture methods, illustrating some recent applications. The body of the paper reviews the main methodological and practical questions raised by the method. We suggest, by way of illustration, how it might be applied to estimating the prevalence of rough sleepers in a given geographical region.  相似文献   
78.
We develop a "perceived hazard" model that estimates consumers' endogenous risk perceptions about products. These perceptions are then linked to a model of product choice. Our approach thus departs from the expected utility model that depends upon external risk assessments. In an application to recreational fishing, we find that anglers' perceived hazards associated with fish consumption advisories do affect product (recreational site) choice. Anglers' perceptions also affect welfare measures because the benefits of contaminant removal flow from these perceptions. The perceived hazard/product choice model is applicable to a wide variety of risky choices consumers face.  相似文献   
79.
Shaw RP 《Population studies》1974,28(1):167-169
Abstract In the notions of the aggregative cost-benefit migration models, this paper questions the assumption that prospective migrants behave as if they are not only concerned with, but are able to calculate expected pecuniary and non-pecuniary returns to re-location. Results of a survey which evaluates the role of cost-return calculations in decisions to migrate suggest that there may be population sub-groups who either do not care to make cost-returns calculations to migration, or who are unable to do so.  相似文献   
80.
Overrepresentation of certain racial/ethnic groups in the foster care system is one of the most troubling and challenging issues in child welfare today. In response, many states have started reporting outcomes by race and ethnicity to identify disproportionately high rates of system contact. The identification of disproportional representation is the first step in developing targeted strategies to address disproportionality--highlighting where resources should be directed and guiding future research. However, present and future efforts to address disproportionality must be accompanied by statistically sound and meaningful methods of measurement. In this article, we argue for the adoption of a relative rate measure of representation--a "Disparity Index"--as the primary instrument for assessing racial disparity in child welfare.  相似文献   
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