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The uniformly most powerful unbiased tests are formulated for the two sample problem of the power series distribution with unknown truncation parameter.  相似文献   
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When the individual measurements are statistically independent, the maximum likelihood estimator calculated at the end of a sequential procedure overestimates the underlying effect. There are many clinical trials in which we are interested in comparing changes in responses between two treatment groups sequentially. Lee and DeMets (1991, JASA 86, 757–762) proposed a group sequential method for comparing rates of change when a response variable is measured for eaeh patient at successive follow-up visits. They assumed that the response follows the linear mixed effects model and derived the asymptotic joint distribution of the sequentially computed statistics. In this article, we consider the maximum likelihood estimator (MLE), the median unbiased estimator (MUE) and the midpoint of a 100(1-α)% confidence interval as point estimators for the rate of change in the linear mixed effects model, and investigate their properties by Monte Carlo simulation.  相似文献   
75.
In this paper, we study the Kullback–Leibler (KL) information of a censored variable, which we will simply call it censored KL information. The censored KL information is shown to have the necessary monotonicity property in addition to inherent properties of nonnegativity and characterization. We also present a representation of the censored KL information in terms of the relative risk and study its relation with the Fisher information in censored data. Finally, we evaluate the estimated censored KL information as a goodness-of-fit test statistic.  相似文献   
76.
This study aims to examine whether and how mobile communication enables citizens to translate their value orientations into their connectedness to the civic life. Specifically, we probe the indirect process in which different types of personal values predict key dimensions of engagement with civic affairs through patterns of mobile phone use. We show that individualism is indirectly associated with engagement with civic affairs through informational mobile use, whereas the link between collectivism and community involvement is positively intervened by relational mobile use. Additionally, socio-tropic empathy yields indirect relationships with civic engagement through informational mobile use. Implications of these findings are discussed.  相似文献   
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Robert M. Park 《Risk analysis》2020,40(12):2561-2571
Uncertainty in model predictions of exposure response at low exposures is a problem for risk assessment. A particular interest is the internal concentration of an agent in biological systems as a function of external exposure concentrations. Physiologically based pharmacokinetic (PBPK) models permit estimation of internal exposure concentrations in target tissues but most assume that model parameters are either fixed or instantaneously dose-dependent. Taking into account response times for biological regulatory mechanisms introduces new dynamic behaviors that have implications for low-dose exposure response in chronic exposure. A simple one-compartment simulation model is described in which internal concentrations summed over time exhibit significant nonlinearity and nonmonotonicity in relation to external concentrations due to delayed up- or downregulation of a metabolic pathway. These behaviors could be the mechanistic basis for homeostasis and for some apparent hormetic effects.  相似文献   
79.
Maintaining the performance of infrastructure-dependent systems in the face of surprises and unknowable risks is a grand challenge. Addressing this issue requires a better understanding of enabling conditions or principles that promote system resilience in a universal way. In this study, a set of such principles is interpreted as a group of interrelated conditions or organizational qualities that, taken together, engender system resilience. The field of resilience engineering identifies basic system or organizational qualities (e.g., abilities for learning) that are associated with enhanced general resilience and has packaged them into a set of principles that should be fostered. However, supporting conditions that give rise to such first-order system qualities remain elusive in the field. An integrative understanding of how such conditions co-occur and fit together to bring about resilience, therefore, has been less clear. This article contributes to addressing this gap by identifying a potentially more comprehensive set of principles for building general resilience in infrastructure-dependent systems. In approaching this aim, we organize scattered notions from across the literature. To reflect the partly self-organizing nature of infrastructure-dependent systems, we compare and synthesize two lines of research on resilience: resilience engineering and social-ecological system resilience. Although some of the principles discussed within the two fields overlap, there are some nuanced differences. By comparing and synthesizing the knowledge developed in them, we recommend an updated set of resilience-enhancing principles for infrastructure-dependent systems. In addition to proposing an expanded list of principles, we illustrate how these principles can co-occur and their interdependencies.  相似文献   
80.
This study reviewed current literature on generational issues in Korea, specifically in relation to the workplace. Based on the results, this study concluded that distinct generations of workers exist in Korea. While there are similar generational characteristics between Korea and the United States because of the unique societal, historical, and cultural factors in each country, there are noticeable differences such as the existence of Generation 386 in Korea. Due to rapid industrialization and social transformation during the past few decades, Korean society seems to exhibit wider gaps between older and younger generations than the United States. The roles of Generation 386 and Generation Y in organizations should be considered for the future.  相似文献   
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