英文化妆品说明书翻译所体现的功能翻译理论

20世纪70年代功能翻译理论开始兴起。它是从翻译的功能和目的出发,强调某一具体翻译目的要求相应的翻译策略、翻译方法,即不同的翻译目的对应不同的翻译方法;为达到某一翻译目的可以采取多种翻译方法,从而回避了诸如直译和意译的两难处境。针对英文化妆品说明书的翻译,通过大量举例分析,从目标、意图和功能三个方面阐述了功能翻译理论的指导作用。     

Empirical evaluation of the implementation of the EMA guideline on missing data in confirmatory clinical trials: Specification of mixed models for longitudinal data in study protocols

In confirmatory clinical trials, the prespecification of the primary analysis model is a universally accepted scientific principle to allow strict control of the type I error. Consequently, both the ICH E9 guideline and the European Medicines Agency (EMA) guideline on missing data in confirmatory clinical trials require that the primary analysis model is defined unambiguously. This requirement applies to mixed models for longitudinal data handling missing data implicitly. To evaluate the compliance with the EMA guideline, we evaluated the model specifications in those clinical study protocols from development phases II and III submitted between 2015 and 2018 to the Ethics Committee at Hannover Medical School under the German Medicinal Products Act, which planned to use a mixed model for longitudinal data in the confirmatory testing strategy. Overall, 39 trials from different types of sponsors and a wide range of therapeutic areas were evaluated. While nearly all protocols specify the fixed and random effects of the analysis model (95%), only 77% give the structure of the covariance matrix used for modeling the repeated measurements. Moreover, the testing method (36%), the estimation method (28%), the computation method (3%), and the fallback strategy (18%) are given by less than half the study protocols. Subgroup analyses indicate that these findings are universal and not specific to clinical trial phases or size of company. Altogether, our results show that guideline compliance is to various degrees poor and consequently, strict type I error rate control at the intended level is not guaranteed.     

Estimating capability index cpk for processes with asymmetric tolerances

Pearn and Chen (1996) considered the process capability index C_pk, and investigated the statistical properties of its natural estimator under various process conditions. Their investigation, however, was restricted to processes with symmetric tolerances. Recently, Pearn and Chen (1998) considered a generalization of C_pk, referred to as C^? _pk, to cover processes with asymmetric tolerances. They investigated the statistical properties of the natural estimator of C^? _pk, and obtained the exact formulae for the expected value and variance. In this paper, we consider a new estimator of C^? _pk, assuming the knowledge on P(LI > T) = p is available, where 0 > p > 1, which can be obtained from historical information of a stable process. We obtain the exact distribution of the new estimator assuming the process characteristic follows the normal distribution. We show that the new estimator is consistent, asymptotically unbiased, which converges to a mixture of two normal distributions. We also show that by adding suitable correction factors to the new estimator, we may obtain the UMVUE and the MLE of the generalization C^? _pk.     

Model Identification in Dynamic Regression (Distributed Lag) Models

Dynamic regression models (also known as distributed lag models) are widely used in engineering for quality control and in economics for forecasting. In this article I propose a procedure for specifying such models in practice. The proposed procedure requires no prewhitening and can directly handle the nonstationary series. Furthermore, the procedure cross-validates prior beliefs about causal relationships between variables with empirical findings to ensure the suitability of model structure. An illustrative example is given.     

Alternative approaches to testing non-nested models with autocorrelated disturbances

Since departures from the classical assumptions regarding the disturbances in a linear tegression model arise frequently in empirical application, deveral computationally Straightforward procedutes are presented in this paper for testiog non-nested models when the disturbances of these models follow first- or higher-order autoregressive processes. Anempirical example is used to illustrate how the procedures may be used to test competing Keynesian and New Classical non-nested models of unemployment for the U.S using annual time series data for 1955-85.     

建设工程监理合同法律关系研究

文章介绍了建设工程监理合同的性质、特征和建设工程监理合同存在的法律关系,分析了损害监理合同法律关系的几种行为,并从明确法律关系、加强立法、完善监理合同的签订与履行和改变费用支付方式四个方面提出了规范不良行为的对策.     

Skewed zero-bound distributions and process capability indices for upper specifications

A common practical situation in process capability analysis, which is not well developed theoretically, is when the quality characteristic of interest has a skewed distribution with a long tail towards relatively large values and an upper specification limit only exists. In such situations, it is not uncommon that the smallest possible value of the characteristic is 0 and this is also the best value to obtain. Hence a target value 0 is assumed to exist. We investigate a new class of process capability indices for this situation. Two estimators of the proposed index are studied and the asymptotic distributions of these estimators are derived. Furthermore, we suggest a decision procedure useful when drawing conclusions about the capability at a given significance level, based on the estimated indices and their asymptotic distributions. A simulation study is also performed, assuming that the quality characteristic is Weibull-distributed, to investigate the true significance level when the sample size is finite.     

How effective are the reset tests for omitted variables

In regression analysis, RESET has widely been regarded as an effective diagnostic test especially for omitted variables. This paper investigates the limitations of the existing RESET tests in detecting omitted variables. We analyze the sources from which RESET draws its power and point out the circumstances under which RESET will likely be ineffective. We offer some Monte Carlo evidence as well as an empirical application to illustrate the weaknesses of the RESET tests. A more robust RESET type test is proposed.