Minimum variance unbiased estimation of stress–strength reliability under bivariate normal and its comparisons

In many industrial and natural phenomena, we need the probability that a component is smaller than the other component. Under a stress–strength model, this is reliability of an item. Under independent setup, there are different approaches for the estimation of such reliability. Here, estimation is considered under the dependent case. Under bi-variate setup uniformly minimum variance unbiased estimator is obtained. Also comparison with available estimator based on Maximum Likelihood Estimate (MLE) is done through Mean Square Error (MSE) and bias. Also these are compared by computing L₁ distance between their distribution functions. From this idea and numerical computations, UMVUE appears to be good.     

A simulation study of methods for selecting subgroup‐specific doses in phase 1 trials

Patient heterogeneity may complicate dose‐finding in phase 1 clinical trials if the dose‐toxicity curves differ between subgroups. Conducting separate trials within subgroups may lead to infeasibly small sample sizes in subgroups having low prevalence. Alternatively,it is not obvious how to conduct a single trial while accounting for heterogeneity. To address this problem,we consider a generalization of the continual reassessment method on the basis of a hierarchical Bayesian dose‐toxicity model that borrows strength between subgroups under the assumption that the subgroups are exchangeable. We evaluate a design using this model that includes subgroup‐specific dose selection and safety rules. A simulation study is presented that includes comparison of this method to 3 alternative approaches,on the basis of nonhierarchical models,that make different types of assumptions about within‐subgroup dose‐toxicity curves. The simulations show that the hierarchical model‐based method is recommended in settings where the dose‐toxicity curves are exchangeable between subgroups. We present practical guidelines for application and provide computer programs for trial simulation and conduct.     

Lurking Behavior in Online Psychosocial Discussion Forums: Theoretical Perspectives and Implications for Practice

Improving outcomes of telebehavioral psychoeducation requires rethinking program design when delivered wholly or partially for self-directed participation. Discussion forum participation often follows the “90-9-1 Rule” where 90% of participants lurk, rather than contribute content. A theoretical perspective on the behavior can help explain its adaptive functions, as well as the threats that this behavior poses to the lurker. Implications for practice require program redesign that actively links individual skills training and group-based discussion. The proposed linking design can synergize individual and group participation to support the development of mutual aid, as well as greater interaction with psychoeducation content and materials.     

Deriving Behavior Model Parameters from Survey Data: Self‐Protective Behavior Adoption During the 2009–2010 Influenza A(H1N1) Pandemic

In this paper, we demonstrate how public opinion surveys can be designed to collect information pertinent to computational behavior modeling, and we present the results of a public opinion and behavior survey conducted during the 2009–2010 H1N1 influenza pandemic. The results are used to parameterize the Health Belief Model of individual health‐protective decision making. Survey subjects were asked questions about their perceptions of the then‐circulating influenza and attitudes towards two personal protective behaviors: vaccination and avoidance of crowds. We empirically address two important issues in applying the Health Belief Model of behavior to computational infectious disease simulation: (1) the factors dynamically influencing the states of the Health Belief Model variables and (2) the appropriateness of the Health Belief Model in describing self‐protective behavior in the context of pandemic influenza.     

Comparison of computer programs for simple linear L 1 regression

A number of efficient computer codes are available for the simple linear L ₁ regression problem. However, a number of these codes can be made more efficient by utilizing the least squares solution. In fact, a couple of available computer programs already do so.

We report the results of a computational study comparing several openly available computer programs for solving the simple linear L ₁ regression problem with and without computing and utilizing a least squares solution.     

The Frisch–Waugh–Lovell theorem for the lasso and the ridge regression

The Frisch–Waugh–Lovell (FWL) (partitioned regression) theorem is essential in regression analysis. This is partly because it is quite useful to derive theoretical results. The lasso regression and the ridge regression, both of which are penalized least-squares regressions, have become popular statistical techniques. This article describes that the FWL theorem remains valid for these penalized least-squares regressions. More precisely, we demonstrate that the covariates corresponding to unpenalized regression parameters in these penalized least-squares regression can be projected out. Some other results related to the FWL theorem in such penalized least-squares regressions are also presented.     

Least squares estimation of varying‐coefficient hazard regression with application to breast cancer dose‐intensity data

To enhance modeling flexibility, the authors propose a nonparametric hazard regression model, for which the ordinary and weighted least squares estimation and inference procedures are studied. The proposed model does not assume any parametric specifications on the covariate effects, which is suitable for exploring the nonlinear interactions between covariates, time and some exposure variable. The authors propose the local ordinary and weighted least squares estimators for the varying‐coefficient functions and establish the corresponding asymptotic normality properties. Simulation studies are conducted to empirically examine the finite‐sample performance of the new methods, and a real data example from a recent breast cancer study is used as an illustration. The Canadian Journal of Statistics 37: 659–674; 2009 © 2009 Statistical Society of Canada     

青海省入境旅游市场的态势分析及预测研究

随着中国入境旅游的迅速发展,青海省的入境旅游呈现出不同的态势。本文从海外游客客源地、客源国等方面对其进行了深入的分析,在此基础上进行了预测,并提出了可行性建议。