Effect of a new selection procedure on adaptive estimation

Adaptive estimation of parameters of some failure time distributionsis considered. A new procedure named the F-procedure has beendeveloped for selecting an appropriate model out of two possible models by Pandey et.al. (1991). Applying this F-procedure adaptive estimatorsof parameters of exponential, Wei bull, inverse Gaussian (IG) and Wald failure time distributions have been proposed in this paper. Comparison of these estimators has been undertaken with MLE's of the respective parameters and with some previous adaptiveestimators by simulation of samples using the Monte Carlo method.Adaptive estimation of parameters of some failure time distributions is considered. A new procedure named the F-procedure has been developedfor selecting an appropriate model out of two possible models by Pandey et.al. (1991). Applying this F-procedure adaptive estimators of parameters of exponential, Wei bull, inverse Gaussian (IG) and Wald failure time distributions have been proposed in this paper. Comparison of these estimators has been undertaken with MLE's of the respective parameters and with some previous adaptive estimators by simulation of samples using the Monte Carlo method.     

Application of the Bootstrap Approach to the Choice of Dimension and the α Parameter in the SIRα Method

To reduce the dimensionality of regression problems, sliced inverse regression approaches make it possible to determine linear combinations of a set of explanatory variables X related to the response variable Y in general semiparametric regression context. From a practical point of view, the determination of a suitable dimension (number of the linear combination of X) is important. In the literature, statistical tests based on the nullity of some eigenvalues have been proposed. Another approach is to consider the quality of the estimation of the effective dimension reduction (EDR) space. The square trace correlation between the true EDR space and its estimate can be used as goodness of estimation. In this article, we focus on the SIR_α method and propose a naïve bootstrap estimation of the square trace correlation criterion. Moreover, this criterion could also select the α parameter in the SIR_α method. We indicate how it can be used in practice. A simulation study is performed to illustrate the behavior of this approach.     

A note on approximate confidence limits for the negative binomial model

Four methods of approximating confidence limits for the single negative binomial parameter, P, are outlined and an empirical study is presented. Some remarks on prediction intervals are also included.     

Semiparametric regression methods for temporal processes subject to multiple sources of censoring

Process regression methodology is underdeveloped relative to the frequency with which pertinent data arise. In this article, the response-190 is a binary indicator process representing the joint event of being alive and remaining in a specific state. The process is indexed by time (e.g., time since diagnosis) and observed continuously. Data of this sort occur frequently in the study of chronic disease. A general area of application involves a recurrent event with non-negligible duration (e.g., hospitalization and associated length of hospital stay) and subject to a terminating event (e.g., death). We propose a semiparametric multiplicative model for the process version of the probability of being alive and in the (transient) state of interest. Under the proposed methods, the regression parameter is estimated through a procedure that does not require estimating the baseline probability. Unlike the majority of process regression methods, the proposed methods accommodate multiple sources of censoring. In particular, we derive a computationally convenient variant of inverse probability of censoring weighting based on the additive hazards model. We show that the regression parameter estimator is asymptotically normal, and that the baseline probability function estimator converges to a Gaussian process. Simulations demonstrate that our estimators have good finite sample performance. We apply our method to national end-stage liver disease data. The Canadian Journal of Statistics 48: 222–237; 2020 © 2019 Statistical Society of Canada     

An Empirical Process View of Inverse Regression

A common approach taken in high‐dimensional regression analysis is sliced inverse regression, which separates the range of the response variable into non‐overlapping regions, called ‘slices’. Asymptotic results are usually shown assuming that the slices are fixed, while in practice, estimators are computed with random slices containing the same number of observations. Based on empirical process theory, we present a unified theoretical framework to study these techniques, and revisit popular inverse regression estimators. Furthermore, we introduce a bootstrap methodology that reproduces the laws of Cramér–von Mises test statistics of interest to model dimension, effects of specified covariates and whether or not a sliced inverse regression estimator is appropriate. Finally, we investigate the accuracy of different bootstrap procedures by means of simulations.     

Uncertainty Analysis for Functional Computer Output: A Simulation Study in Inverse Problems

Computer models with functional output are omnipresent throughout science and engineering. Most often the computer model is treated as a black-box and information about the underlying mathematical model is not exploited in statistical analyses. Consequently, general-purpose bases such as wavelets are typically used to describe the main characteristics of the functional output. In this article we advocate for using information about the underlying mathematical model in order to choose a better basis for the functional output. To validate this choice, a simulation study is presented in the context of uncertainty analysis for a computer model from inverse Sturm-Liouville problems.     

Bayesian Conditional Mean Estimation in Log‐Normal Linear Regression Models with Finite Quadratic Expected Loss

Log‐normal linear regression models are popular in many fields of research. Bayesian estimation of the conditional mean of the dependent variable is problematic as many choices of the prior for the variance (on the log‐scale) lead to posterior distributions with no finite moments. We propose a generalized inverse Gaussian prior for this variance and derive the conditions on the prior parameters that yield posterior distributions of the conditional mean of the dependent variable with finite moments up to a pre‐specified order. The conditions depend on one of the three parameters of the suggested prior; the other two have an influence on inferences for small and medium sample sizes. A second goal of this paper is to discuss how to choose these parameters according to different criteria including the optimization of frequentist properties of posterior means.     

A Proportional Hazards Regression Model for the Subdistribution with Covariates‐adjusted Censoring Weight for Competing Risks Data

With competing risks data, one often needs to assess the treatment and covariate effects on the cumulative incidence function. Fine and Gray proposed a proportional hazards regression model for the subdistribution of a competing risk with the assumption that the censoring distribution and the covariates are independent. Covariate‐dependent censoring sometimes occurs in medical studies. In this paper, we study the proportional hazards regression model for the subdistribution of a competing risk with proper adjustments for covariate‐dependent censoring. We consider a covariate‐adjusted weight function by fitting the Cox model for the censoring distribution and using the predictive probability for each individual. Our simulation study shows that the covariate‐adjusted weight estimator is basically unbiased when the censoring time depends on the covariates, and the covariate‐adjusted weight approach works well for the variance estimator as well. We illustrate our methods with bone marrow transplant data from the Center for International Blood and Marrow Transplant Research. Here, cancer relapse and death in complete remission are two competing risks.     

Combining Inverse Probability Weighting and Multiple Imputation to Improve Robustness of Estimation

Inverse probability weighting (IPW) and multiple imputation are two widely adopted approaches dealing with missing data. The former models the selection probability, and the latter models data distribution. Consistent estimation requires correct specification of corresponding models. Although the augmented IPW method provides an extra layer of protection on consistency, it is usually not sufficient in practice as the true data‐generating process is unknown. This paper proposes a method combining the two approaches in the same spirit of calibration in sampling survey literature. Multiple models for both the selection probability and data distribution can be simultaneously accounted for, and the resulting estimator is consistent if any model is correctly specified. The proposed method is within the framework of estimating equations and is general enough to cover regression analysis with missing outcomes and/or missing covariates. Results on both theoretical and numerical investigation are provided.