用固体分散法提高磺胺嘧啶片溶出速度的研究

为了提高磺胺嘧啶（SD）在水中的溶解度、溶出速度,加速其在体内的崩解、溶出、吸收过程,达到速效、高效的目的,以PEG－6000、尿素等材料为载体,采取溶剂熔融法,制备SD的固体分散体,分别测定了固体分散体与原料药的溶解度以及固体分散体片剂与普通片剂的溶出度和溶出速率,固体分散体片剂的溶出度均达到99．0％以上,而普通片剂的最大熔出度为26％,方差分析固体分散体片剂组与普通片剂组具有极显著差异（P＜0．01）,固体分散体能显著提高血的溶解度和溶出速度。     

Single Mothers Always Lose? Union Dissolution and Perceived Changes in Material Well-Being in Lithuania

The article investigates the perceived changes in material well-being of single mothers due to union dissolution in Lithuania. The analysis is based on a nationally representative data set; our sample includes 415 single mothers with underaged children. At the core of the analysis is the effect of socioeconomic standing on the assessment of changes. I use the level of education as the proxy variable for the measurement of socioeconomic position and consider education on the individual and ex-couple level. The decline of material conditions after union dissolution was reported by 45% of the sample. The main results, based on the multivariate analysis, indicate the most negative effect of union dissolution for women from the educationally heterogeneous ex-couples, where women’s education was lower than men’s. Thus, union dissolution most negatively affects women, who were economically dependent in the previous partnership. Contrary to our expectation, we did not find any significant association between women’s education and the assessment of the changes in material well-being. However, ex-partner’s education is a significant predictor and shows the highest risk of reporting negative changes for women previously partnered with university-educated men. On a more general level, the article highlights the importance of the subjective indicators in the analysis of economic divorce outcomes.     

Pathways of Commitment to Wed: The Development and Dissolution of Romantic Relationships

The authors used changes in commitment to wed and reasons for these changes to classify couples into developmental pathways. Using data from a random sample of dating couples (N = 376), they found 4 distinct commitment processes: (a) dramatic, (b) conflict ridden, (c) socially involved, and (d) partner focused. Dramatic commitments were defined by relatively frequent fluctuations in commitment and negative attributions about their relationships. Conflict‐ridden commitments were defined by high levels of conflict and relatively frequent decreases in commitment. Individuals in socially involved commitments reported the highest proportion of positive dyadic attributions and references to joint interaction with social networks. Those in partner‐focused commitments reported a high proportion of positive dyadic attributions and references to interaction with partners. Types also differed on important relational variables, including satisfaction, love, ambivalence, worries about marriage, and leisure. Dramatic commitments were more likely than any other type to break up and showed an increased likelihood of regression in stage of involvement.     

公司僵局的困境解析与路径建构——以司法解散的替代性措施为视角

公司是市场经济发展的产物，兼具资源整合与经营效率于一体。公司僵局法律救济制度的构建，是我国立法、司法活动的重要内容。由于我国的公司组织形式发展较晚，对于破解公司僵局的研究尚处于起步阶段，不够具体与全面，给司法实践造成许多困难。而目前规定的司法解散制度，暴力地解决了公司僵局问题，却阻碍了挽救公司存续的可能，并且该制度在实践中适用的标准不一，难以对症下药。