Subgroup Analysis with Time‐to‐Event Data Under a Logistic‐Cox Mixture Model

Subgroup detection has received increasing attention recently in different fields such as clinical trials, public management and market segmentation analysis. In these fields, people often face time‐to‐event data, which are commonly subject to right censoring. This paper proposes a semiparametric Logistic‐Cox mixture model for subgroup analysis when the interested outcome is event time with right censoring. The proposed method mainly consists of a likelihood ratio‐based testing procedure for testing the existence of subgroups. The expectation–maximization iteration is applied to improve the testing power, and a model‐based bootstrap approach is developed to implement the testing procedure. When there exist subgroups, one can also use the proposed model to estimate the subgroup effect and construct predictive scores for the subgroup membership. The large sample properties of the proposed method are studied. The finite sample performance of the proposed method is assessed by simulation studies. A real data example is also provided for illustration.     

Assessing the effects of land use and land cover patterns on thermal conditions using landscape metrics in city of Indianapolis,United States

Direct applications of remote sensing thermal infrared (TIR) data in landscape ecological research are rare due to limitations in the sensors, calibration, and difficulty in interpretation. Currently there is a general lack of methodology for examining the relationship between land surface temperatures (LST) derived from TIR data and landscape patterns extracted from optical sensors. A separation of landscapes into values directly related to their scale and signature is a key step. In this study, a Landsat ETM+ image of Indianapolis, Unites States, acquired on June 22, 2000, was spectrally unmixed (using spectral mixture analysis, SMA) into fraction endmembers of green vegetation, soil, high albedo, and low albedo. Impervious surface was then computed from the high and low albedo images. A hybrid classification procedure was developed to classify the fraction images into seven land use and land cover (LULC) classes. Using the fractional images, the landscape composition and pattern were examined. Next, pixel-based LST measurements were correlated with the landscape fractional components to investigate LULC based relationships between LST and impervious surface and green vegetation fractions. An examination of the relationship between the LULC and LST maps with landscape metrics was finally conducted to deepen understanding of their interactions. Results indicate that SMA-derived fraction images were effective for quantifying the urban morphology and for providing reliable measurements of biophysical variables. LST was found to be positively correlated with impervious surface fraction but negatively correlated with green vegetation fraction. Each temperature zone was associated with a dominant LULC category. Further research should be directed to the theoretical and applied implications of describing such relationships between LULC patterns and urban thermal conditions.

The umvue and bayes estimate of reliability of mixed failure time distribution

We study the reliability estimates of the non-standard mixture of degenerate (degenerated at zero) and exponential distributions. The Uniformly Minimum Variance Unbiased Estimator (UMVUE) and Bayes estimator of the reliability for some selective prior when the mixing proportion is known and unknown are derived. The Bayes risk is computed for each Bayes estimator of the reliability. A simulated study is carried out to assess the performance of the estimators alongwith the true and Maximum Likelihood Estimate (MLE) of the reliability. An example from Vannman (1991) is also discussed at the end of the paper.     

RELIABILITY PROPERTIES OF SERIES AND PARALLEL SYSTEMS FROM BIVARIATE EXPONENTIAL MODELS

ABSTRACT

In this paper we study the classification of the generalized mixtures of two or three exponential distributions, in the ILR and DLR classes, and consequently in the IFR and DFR classes. We apply these results to classify the aging of the series and parallel systems, in accord with some common bivariate exponential models of their components.     

Heterogeneity in Parent‐reported Social Skill Development in Early Elementary School Children

Despite known risks associated with aberrant social skill development, there has been a relative dearth of literature on typical developmental changes in social skills over time. In this study, we examine systematic changes in social skills from kindergarten (typical age of 5–6 years) to third grade (typical age of 8–9 years), and focus on systematic heterogeneity across these developmental trajectories. Data came from the National Head Start—Public School Early Childhood Transition Demonstration Project (N = 6964). Mixture models provide evidence for multiple classes of individuals representing heterogeneity in the development of social skills. Classes were defined as a majority class (whose trajectories remained relatively stable over time), an increasing class (whose trajectories increased at a faster rate than the majority class), and a decreasing class (whose trajectories decreased at a faster rate than the majority class). Developmental trends accounted for a substantial proportion of the variance in social skill components. Implications and limitations of the study are discussed.     

掺合尾矿砂混凝土新坝体材料配合比试验研究

借鉴特细砂混凝土配制规律,进行铁尾矿砂与天然砂混合使用试验.结果表明混合比例适宜的混合砂可以配置出性能优良的混凝土,这可缓解混凝土行业天然砂资源的匮乏压力,存在很大的研究利用价值.     

A graphical method for evaluating mixture designs with respect to the slope

Good estimation of the slopes of the mixture response function may be important as well as estimation of mean mixture response. It is possible to evaluate and compare several mixture designs with respect to the slope. A graphical method is proposed that allows us to evaluate a given design's support for the fitted model in terms of slope variance. We can plot variances of slopes along Cox direction or axial direction according to existence of restriction of simplex region or not when comparing several different mixture designs.     

An introduction to relationship algebras

Since the introduction and definition of relationship algebras by James (1957), rolatively little use has been made of this theory in experimental design and analysis problems This may be due to the underlying theory of relationship algebras being previously accessible only in books on mathematical structure theory, e.g. van der Waerden (1950) This paper provides a development of the theory of relationship algebras beginning at an elementray level and including only those parts of mathematical structure theory which are essential to this development. An example of its application in derving an analysis due to alling (1967) is presented.