Combining the Social Relations Model and Behavioral Genetics to Explore the Etiology of Familial Interactions

SUMMARY

This review focuses on the Social Relations Model (SRM) and a genetic extension of this model as one approach for identifying the processes by which genetic factors influence familial exchanges (Kenny & La Voie, 1984). The basic SRM and its ability to decompose dyadic measures of family interaction into actor, partner and dyadic relationship effects is described followed by findings from 3 recent studies. Results indicate that much of familial interaction is in fact relationship specific, and not due to individual-level effects. We also discuss why and how the basic SRM is enriched through the incorporation of genetically sensitive designs and present results that suggest the importance of nonshared environmental contributions for both individual and dyadic level effects. Finally, directions for future family research are proposed including the use of genetically informative designs, the collection of round-robin robin data, and the incorporation of more diverse samples.     

The multistate stable population model with immigration

This paper outlines the discrete‐time and continuous‐time formulations of the stable population model with immigration, showing their commonality. It then illustrates how the model can be extended to include multiple interacting populations, and goes on to consider a multistate version of reproductive value that further illuminates the evolutionary dynamics of an “open”; model of multistate population growth and redistribution. Attention is restricted to results arising from a fertility regime that is below replacement level.     

Gender and Age Differences in Child Adjustment to Parental Separation

Abstract

The present study examined gender and age differences in adjustment among children whose parents have separated. Measures designed specifically to assess family functioning during the divorce process (the Divorce Adjustment Inventory-Revised, and Child Divorce Adjustment Inventory), along with a measure of self-esteem and interviews with children, provide an in-depth exploration of the experience of families during the transitional period of separation. Results indicate that (1) parents of girls reported higher resolution of the separation, (2) high self-esteem for girls was mediated by residential parents' high socioeconomic status, (3) older children exhibited higher adjustment than younger children, and (4) father-headed families indicated higher adjustment before and after separation. Using a model of divorce as a process, results are discussed in relation to findings from studies of post-divorce and pre-separation families to provide a more complete picture of the divorce experience and child adjustment to that experience.     

A comparison of subgroup identification methods in clinical drug development: Simulation study and regulatory considerations

With advancement of technologies such as genomic sequencing, predictive biomarkers have become a useful tool for the development of personalized medicine. Predictive biomarkers can be used to select subsets of patients, which are most likely to benefit from a treatment. A number of approaches for subgroup identification were proposed over the last years. Although overviews of subgroup identification methods are available, systematic comparisons of their performance in simulation studies are rare. Interaction trees (IT), model‐based recursive partitioning, subgroup identification based on differential effect, simultaneous threshold interaction modeling algorithm (STIMA), and adaptive refinement by directed peeling were proposed for subgroup identification. We compared these methods in a simulation study using a structured approach. In order to identify a target population for subsequent trials, a selection of the identified subgroups is needed. Therefore, we propose a subgroup criterion leading to a target subgroup consisting of the identified subgroups with an estimated treatment difference no less than a pre‐specified threshold. In our simulation study, we evaluated these methods by considering measures for binary classification, like sensitivity and specificity. In settings with large effects or huge sample sizes, most methods perform well. For more realistic settings in drug development involving data from a single trial only, however, none of the methods seems suitable for selecting a target population. Using the subgroup criterion as alternative to the proposed pruning procedures, STIMA and IT can improve their performance in some settings. The methods and the subgroup criterion are illustrated by an application in amyotrophic lateral sclerosis.     

Work Productivity as a Function of the Percentage of Monetary Incentives to Base Pay

In many individual monetary incentive systems workers receive an hourly base pay and can earn incentives when productivity exceeds a specified standard. The total amount that can be earned in incentives is often expressed as a percentage of base pay. This study examined the effects of different percentages of incentive pay to base pay on work productivity. Seventy-five college students were randomly assigned to one of five incentivebase pay conditions: 0% (no incentives), l0%, 30%. 60% or 100%. Subjects participated in 15 forty-five minute sessions during which they assem: bled parts made from bolts, nuts and washers. Subjects received a base pay amount for assembling a minimum of 50 quality parts per session and a per piece incentive for parts over 50. If subjects assernbled 120 quality parts, the production maximum, the total amount they could earn in incentives equaled 0%, l0%, 30%, 60% or 100% of their base pay. Results indicated that the productivity of subjects in the l0%, 30%, 60% and 100% groups was significantly greater than that of subjects in the 0% incentive group; however, the productivity of subjects in the l0%, 30%, 60% and 100% incentive groups did not differ.     

Peer and Selection Effects on Youth Smoking in California

Previous research has found that youth smoking choices are strongly influenced by peer smoking. However, these studies often fail to account for simultaneity and nonrandom peer selection. This article describes an equilibrium model of peer effects that incorporates both of these features, and estimates its parameters using data on California teenagers. Identification is aided by using the influence of observable variables on group selection as a proxy for the influence of unobservables. I find that the effect of peer smoking on the decision to smoke is much weaker than found in previous studies.     

康德哲学与现代性论争

康德的批判哲学是当今现代性论争的焦点之一。现代性重建派只强调康德哲学中的知性立法的一面 ,而忽视了理性的规范作用。后现代主义则与之相反。其实 ,双方都歪曲了康德有关知性立法和理性规范的论述的本意。康德是要指出知性立法和理性规范是相互制衡的 ,也即互相渗透和互为解放力量的。因而 ,现代性危机的原因不在于现代社会的工具理性化 ,这只是表面现象 ,而在于知性立法和理性规范之间互相制衡的机制遭到了破坏     

Parasitoid-mediated effects: apparent competition and the persistence of host–parasitoid assemblages

Indirect effects such as apparent competition (in which two hosts that do not compete for resources interact via a shared natural enemy) are increasingly being shown to be prevalent in the structure and function of ecological assemblages. Here, we review the empirical and theoretical evidence for these enemy-mediated effects in host–parasitoid assemblages. We first address questions about the design of experiments to test for apparent competition. Second, we consider factors likely to affect the coexistence of host species that share a parasitoid and are involved in apparent competition. We show that parasitoid aggregation, and the switching effect that this can generate when hosts occur in separate patches, not only promotes persistence but is also strongly stabilizing. The broader consequences of these effects are discussed. Received: November 6, 1998 / Accepted: January 13, 1999     

Intergenerational Interaction Through Reminiscence Processes

Abstract

Introduction: The interest in intergenerational programmes is increasing. However, there is a need for evaluation and the development of a theoretical framework to explain the mechanism of changes in attitudes of participants which is the purpose of this paper.

Method: From July to December 2002 an intergenerational intervention was conducted with 111 students and 32 elders, who shared their life stories during class time. A Focus group technique was used to evaluate the programme and a theoretical framework was developed to explain the mechanism of changes in attitudes of adolescents towards elders and the attitudes of elders towards adolescents.

Results: The results showed that stereotypes and prejudice exist, from young people towards elders and from elders towards young ones. The theoretical framework developed showed why and how participants changed their views towards each other in an intergenerational programme using reminiscence processes as a means of interaction.

Conclusion: Although the study had some limitations, it was valuable in showing that older people had some negative images of adolescents. It also showed why and how participants changed their view towards each other.     

Puzzling pieces: a sensory design learning tool

ABSTRACT

This article gives an account of an activity that is part of a collection of instructional materials for learning about sensory aspects of design for products, environments, and services. It describes the participants’ experiences and reflections in a workshop at DeSForM, the 10th Conference on Design and Semantics of Form and Movement. The article highlights the participants’ engagement with one of the exploratory activities, Puzzling Pieces, that was in the process of being developed. The unique ways in which the attendees translated theoretical multi-sensory design perspectives into activities for heightening multi-sensory awareness and consciousness of sensory interactions suggest that this activity may be a useful tool for finetuning the sensory design process.