The effect of non-normal disturbances and conditional heteroskedasticity on multiple cointegration tests

!t is well-known that Johansen's multiple cointegration tests' results and those of Johansen and Juselius' tests for restricrions on cointegrating vectors and their weights have far-reaching implications for economic modelling and analysis. Therefore, it is important to ensure that the tests have desirable finite sample properties. Although the statistics are derived under Gaussian distribution,the asympotic results are derived under a much wider class of distributions. Using simulation, this paper investigates the effect of non-normal disturbances on these tests in finite samples. Further, ARCH/GARCH type conditional heteroskedasticity is present in many economic and financial time series. This paper examines the finite properties of the tests when the error term follows ARCH/GARCH type processes. From the evidence, it appears that researchers should not be overly concerned by the possibility of small departures from non-normality when using Johansen's suggested techniques even in finite samples. ARCH and GARCH effects may be more problematic, however. In particular it becomes more important ro test whether the restriction implicit in the integrated (or near-integrated) ARCH-type Drocess actually holds in time series for the application of the cointegraiion rank tests and the test for restrictions on cointegrating weights. The tests for restrictions on cointegrating vectors apper to be robust for non-normal errors and for all ARCH and GARCH type processes considered.     

Relations among three parametric multiple testing methods for correlated tests

Multiple endpoints in clinical trials are usually correlated. To control the family-wise type I error rate, both Huque and Alosh's flexible fixed-sequence (FFS) testing method and Li and Mehrotra's adaptive α allocation approach (4A) have taken into account correlations among endpoints. I suggested a weighted multiple testing correction (WMTC) for correlated tests and compared it with FFS. However, the relationship between the 4A method and the FFS method or the relationship between the 4A method and the WMTC method has not been studied. In this paper, simulations are conducted to investigate these relationships. Tentative guidelines to help choosing an appropriate method are provided.     

Models Comparison for Step-Stress Accelerated Life Testing

In this article, four basic models for step-stress accelerated life testing are introduced and compared: cumulative exposure model (CEM), linear cumulative exposure model (LCEM), tampered random variable model (TRVM), and tampered failure rate model (TFRM). Limitations of the four models are also introduced for better use of the models.     

On testing for an identity covariance matrix when the dimensionality equals or exceeds the sample size

This article explores the problem of testing the hypothesis that the covariance matrix is an identity matrix when the dimensionality is equal to the sample size or larger. Two new test statistics are proposed under comparable assumptions to those statistics in the literature. The asymptotic distribution of the proposed test statistics are found and are shown to be consistent in the general asymptotic framework. An extensive simulation study shows the newly proposed tests are comparable to, and in some cases more powerful than, the tests for an identity covariance matrix currently in the literature.     

On adaptive procedures controlling the familywise error rate

The idea of modifying, and potentially improving, classical multiple testing methods controlling the familywise error rate (FWER) via an estimate of the unknown number of true null hypotheses has been around for a long time without a formal answer to the question whether or not such adaptive methods ultimately maintain the strong control of FWER, until Finner and Gontscharuk (2009) and Guo (2009) have offered some answers. A class of adaptive Bonferroni and S?idàk methods larger than considered in those papers is introduced, with the FWER control now proved under a weaker distributional setup. Numerical results show that there are versions of adaptive Bonferroni and S?idàk methods that can perform better under certain positive dependence situations than those previously considered. A different adaptive Holm method and its stepup analog, referred to as an adaptive Hochberg method, are also introduced, and their FWER control is proved asymptotically, as in those papers. These adaptive Holm and Hochberg methods are numerically seen to often outperform the previously considered adaptive Holm method.     

Bayesian inference on multiply sequential order statistics from heterogeneous exponential populations with GLR test for homogeneity

In this article, sequential order statistics (SOS) coming from heterogeneous exponential distributions are considered. Maximum likelihood and Bayesian estimates of parameters are derived on the basis of multiple SOS samples. Admissibility of the Bayes estimates are discussed and proved by the well-known Blyth’s lemma. Based on the available data, confidence intervals and highest posterior density credible sets are obtained. The generalized likelihood ratio (GLRT) and the Bayesian tests (under the “0 ? K” loss function) are derived for testing homogeneity of the exponential populations. It is shown that the GLRT in this case is scale invariant. Some guidelines for deriving the uniformly most powerful scale-invariant test (if exists) are also given.     

Generalized Mann–Whitney Type Tests for Microarray Experiments

New statistical procedures are introduced to analyse typical microRNA expression data sets. For each separate microRNA expression, the null hypothesis to be tested is that there is no difference between the distributions of the expression in different groups. The test statistics are then constructed having certain type of alternatives in mind. To avoid strong (parametric) distributional assumptions, the alternatives are formulated using probabilities of different orders of pairs or triples of observations coming from different groups, and the test statistics are then constructed using corresponding several‐sample U‐statistics, natural estimates of these probabilities. Classical several‐sample rank test statistics, such as the Kruskal–Wallis and Jonckheere–Terpstra tests, are special cases in our approach. Also, as the number of variables (microRNAs) is huge, we confront a serious simultaneous testing problem. Different approaches to control the family‐wise error rate or the false discovery rate are shortly discussed, and it is shown how the Chen–Stein theorem can be used to show that family‐wise error rate can be controlled for cluster‐dependent microRNAs under weak assumptions. The theory is illustrated with an analysis of real data, a microRNA expression data set on Finnish (aggressive and non‐aggressive) prostate cancer patients and their controls.