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1.
In studies with recurrent event endpoints, misspecified assumptions of event rates or dispersion can lead to underpowered trials or overexposure of patients. Specification of overdispersion is often a particular problem as it is usually not reported in clinical trial publications. Changing event rates over the years have been described for some diseases, adding to the uncertainty in planning. To mitigate the risks of inadequate sample sizes, internal pilot study designs have been proposed with a preference for blinded sample size reestimation procedures, as they generally do not affect the type I error rate and maintain trial integrity. Blinded sample size reestimation procedures are available for trials with recurrent events as endpoints. However, the variance in the reestimated sample size can be considerable in particular with early sample size reviews. Motivated by a randomized controlled trial in paediatric multiple sclerosis, a rare neurological condition in children, we apply the concept of blinded continuous monitoring of information, which is known to reduce the variance in the resulting sample size. Assuming negative binomial distributions for the counts of recurrent relapses, we derive information criteria and propose blinded continuous monitoring procedures. The operating characteristics of these are assessed in Monte Carlo trial simulations demonstrating favourable properties with regard to type I error rate, power, and stopping time, ie, sample size.  相似文献   
2.
ABSTRACT

Educational institutions are an important setting where psychological, pedagogical, sociocultural, and language adaptation of immigrant children occurs. A number of teaching strategies, practices, approaches, and methods have been described in the literature. In the Russian context, such strategies have been called ‘technologies’. The purpose of the present exploratory study was to describe teaching technologies used by teachers in Russia when working with immigrant students in elementary schools. Responses of forty-five elementary school teachers to open-ended questions describing technologies they use when teaching children with migration backgrounds were analyzed using content analysis. Findings suggest that Russian elementary school teachers used ethno-cultural group, communicative technologies, games, individualized instruction, and differentiated teaching. Many approaches mentioned can be used inclusively with groups of immigrant and non-immigrant students. Importantly, while teachers supplemented classroom instruction with additional Russian language lessons, none mentioned specific techniques for teaching Russian as a non-native language. These findings are discussed in relation to teaching strategies described in the international literature focused on migrant students. Finally, implications for further research are discussed.  相似文献   
3.

Problem

Research suggests that the skill and experience of the attendant significantly affect the outcomes of vaginal breech births, yet practitioner experience levels are minimal within many contemporary maternity care systems.

Background

Due to minimal experience and cultural resistance, few practitioners offer vaginal breech birth, and many practice guidelines and training programmes recommend delivery techniques requiring supine maternal position. Fewer practitioners have skills to support physiological breech birth, involving active maternal movement and choice of birthing position, including upright postures such as kneeling, standing, squatting, or on a birth stool. How professionals learn complex skills contrary to those taught in their local practice settings is unclear.

Question

How do professionals develop competence and expertise in physiological breech birth?

Methods

Nine midwives and five obstetricians with experience facilitating upright physiological breech births participated in semi-structured interviews. Data were analysed iteratively using constructivist grounded theory methods to develop an empirical theory of physiological breech skill acquisition.

Results

Among the participants in this research, the deliberate acquisition of competence in physiological breech birth included stages of affinity with physiological birth, critical awareness, intention, identity and responsibility. Expert practitioners operating across local and national boundaries guided less experienced practitioners.

Discussion

The results depict a specialist learning model which could be formalised in sympathetic training programmes, and evaluated. It may also be relevant to developing competence in other specialist/expert roles and innovative practices.

Conclusion

Deliberate development of local communities of practice may support professionals to acquire elusive breech skills in a sustainable way.  相似文献   
4.
5.
Over the years, noteworthy social workers have been interviewed for the Clinical Social Work Journal. This article features an interview with Joyce Edward who is recognized for her many extraordinary contributions to clinical social work. Joyce has co-written or co-edited three exceptional books for the social work clinician, she has been an esteemed teacher and a vocal activist for quality mental health care. In this interview Joyce reflects on family influences, her work as a social caseworker, the psychoanalytic luminaries with whom she trained, her concerns about the clinical education of today's social work students, and finally, her perspective on managed mental health care.  相似文献   
6.
运用心理学移情原理消除师生的情感障碍   总被引:5,自引:0,他引:5  
英语教学的成败是诸多因素相互作用的结果 ,但无论这些因素多么错综复杂 ,主要还是来自教和学两方面。教师和学生能否在教学中相互理解从而形成互动是教学成败的关键。文章将着重讨论师生间营造互动关系中的两个重要环节———情感与移情  相似文献   
7.
深大外语系把若干计算机软件应用于英语专业本科学生的写作课教材系列。这不仅有助于学生自修写作技巧,且能为教师节省大量时间,使教师有可能对学生作更多的个别辅导。同时,学生在上写作课的过程中还能掌握一种使用计算机的实际技能。近十年来,中国的飞速发展是史无前例的。西方的技术发展史对中国虽然有启迪作用,但其实际要求与中国相去甚远。在这个意义上,深大的尝试对全中国均具有示范意义。  相似文献   
8.
英语口语技能是听、说、读、写四项基本语言技能中很重要的一种技能。要通过课堂教学提高学生口语能力 ,必须从教师、教学方法和学生三方面入手 ,即教师应组织和动员学生积极参与学习 ,采取循序渐进的教学方法 ,发挥学生的主观能动性。学生应有明确的学习目标和计划 ,积极配合老师 ,多说勤炼  相似文献   
9.
初探高校教学与科研的良性循环   总被引:1,自引:0,他引:1  
正确认识和处理好教学与科研相互依存和相互矛盾的关系及制约这一关系的诸多因素 ,才能实现高校的人才培养和科研成果双丰收 ,促进教学与科研的良性循环  相似文献   
10.
非文科专业人文社会科学教学改革是时代的呼唤和社会可持续发展的现实要求 ,是 2 1世纪高等教育发展的历史趋势 ,是我国社会主义现代化建设事业的客观需要。  相似文献   
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