Meningococcal serogroup B outbreak response University of Wisconsin-Madison

A meningococcal serogroup B (MenB) outbreak at a large public university prompted an emergency response to immunize undergraduates. Objective: To report on a successful meningococcal serogroup B (MenB) vaccine clinic response at a large public university. Methods: We assembled the team leaders to write this case report. Results: Activation of the emergency plan and points of dispensing required cooperation of many units on campus under the leadership of university health officials with support from Centers for Disease Control and Prevention, state division of public health and the city-county health department. Significant efforts to provide consistent messages to students and parents regarding the outbreak and the availability of the MenB vaccines were made. Volunteers were recruited to staff the clinics alongside university healthcare providers. Over 22,000 doses of vaccine were administered. Conclusion: We report our experience and lessons learned which may be helpful to universities in preventing and responding to disease outbreaks.     

Does biomass energy consumption reduce total energy CO2 emissions in the US?

This study investigates the causal relationship between total biomass energy consumption, total energy CO₂ emissions, and GDP in the United States for the period January 1973–December 2016 by employing a directed acyclic graph (DAG) techniques and the Autoregressive Distributed Lag (ARDL) model. Additionally, this paper examines the existence of the environmental Kuznets curve (EKC) hypothesis. The result of the DAG reveals that total biomass energy consumption and GDP have a unidirectional contemporaneous causal relationship with total energy CO₂ emissions. Based on the results of the ARDL, we find that a 1% increase in per capita total biomass energy consumption causes a 0.65% reduction in per capita total energy CO₂ emissions in the long-run. This finding implies that expanding the usage of biomass is one way to reduce and control greenhouse gases in the US. Moreover, we find that the inverted U-shaped EKC hypothesis is satisfied for the US case. Findings from this study suggest that energy policies should stimulate an increase of biomass production for reducing total energy CO₂.     

Adherence to three different strategies to prevent early onset GBS infection in newborns

ProblemDespite the introduction of preventive guidelines, no decrease in the incidence of early onset infection was observed.BackgroundEarly onset group B streptococcal (EOGBS) infection is an important cause of neonatal morbidity and mortality.AimOur study was conducted to determine adherence to three guideline-based group B streptococcus (GBS) preventive strategies.MethodsA prospective experimental study clustered by obstetric collaboration region was performed between March 2013 and August 2014 among midwives, obstetricians and paediatricians in the Netherlands. At baseline, the three regions operated according to the Dutch preventive strategy (founded on the risk-based strategy) in order to prevent EOGBS infection, whereas in the study period they followed either the risk-based, the combination or the Dutch strategy. Adherence was measured prospectively per pregnant woman, using predefined core elements of each preventive strategy: identification of risk factors, maternal GBS screening, application of intrapartum antibiotic prophylaxis and observation of the child. Data about adherence to the core elements were collected from medical records, maternal questionnaires and laboratory test results.FindingsIn the three regions, a total of 121 care providers and 1562 women participated.We found an overall adherence of 90% to the risk-based strategy, 57% to the combination strategy and 89% to the Dutch strategy. Adherence to a strategy in case women had EOGBS risk factors was below 20% in all strategies.DiscussionThe majority of women with EOGBS risk factors did not receive the care prescribed by any of three preventive strategies and were not treated optimally.ConclusionThe risk-based and the Dutch strategy are the recommended strategies for implementation.     

Feature screening in ultrahigh-dimensional additive Cox model

The additive Cox model is flexible and powerful for modelling the dynamic changes of regression coefficients in the survival analysis. This paper is concerned with feature screening for the additive Cox model with ultrahigh-dimensional covariates. The proposed screening procedure can effectively identify active predictors. That is, with probability tending to one, the selected variable set includes the actual active predictors. In order to carry out the proposed procedure, we propose an effective algorithm and establish the ascent property of the proposed algorithm. We further prove that the proposed procedure possesses the sure screening property. Furthermore, we examine the finite sample performance of the proposed procedure via Monte Carlo simulations, and illustrate the proposed procedure by a real data example.     

手动爬楼梯轮椅的运动过程分析

对一种手动爬楼梯轮椅的运动过程进行了分析。在各部件不与楼梯台阶相干涉的条件下，计算出了车辆质心位置的座标值，并依此绘出质心的位移轨迹曲线。计算了轮椅在上爬楼梯时运动期的中间段质心的速度、加速度以及人的操纵力值。为进一步进行动力学分析和轮椅的改进设计提供了依据。     

使用PC1D 5.9模拟高效单晶硅太阳能电池

介绍了使用PC1D 5.9软件模拟高效单晶硅太阳能电池的方法。通过建立太阳能电池的结构模型和参数模型,在模拟的电池测试环境下,仿真得到太阳能电池的电压-电流曲线和量子效率曲线,并根据太阳能电池的理论,计算填充因子和转换效率的值。     

Lawrence R. Klein 1920–2013: Notes on the early years

Klein can well be said to have created the field of macroeconometric modeling almost singlehandedly. His international influence started at an early stage. The article offers scattered archive observations on Klein's early years from undergraduate study to the University of Pennsylvania in 1958. Klein was in 1944 recruited by the Cowles Commission in Chicago to construct the first macroeconomic model in the USA, drawing on the experiences of the interwar modeling work of Jan Tinbergen and the new path-breaking econometric methods developed by Trygve Haavelmo. The first Klein model was taken into use at the end of 1945 to shed light on the prospects for the US economy in the transition from war to peace. After two-three years in Chicago Chicago, Klein traveled for a year in Europe and initiated macroeconometric modeling work in Canada, at the University of Michigan, and at Oxford University. This was only the beginning of the lifelong influence exerted on modelers around the globe. The article pays attention to Klein's relation to Paul Samuelson, Jacob Marschak, Trygve Haavelmo, Ragnar Frisch, and others.     

A Semiparametric Regression Model for Longitudinal Data with Non‐stationary Errors

Motivated by the need to analyze the National Longitudinal Surveys data, we propose a new semiparametric longitudinal mean‐covariance model in which the effects on dependent variable of some explanatory variables are linear and others are non‐linear, while the within‐subject correlations are modelled by a non‐stationary autoregressive error structure. We develop an estimation machinery based on least squares technique by approximating non‐parametric functions via B‐spline expansions and establish the asymptotic normality of parametric estimators as well as the rate of convergence for the non‐parametric estimators. We further advocate a new model selection strategy in the varying‐coefficient model framework, for distinguishing whether a component is significant and subsequently whether it is linear or non‐linear. Besides, the proposed method can also be employed for identifying the true order of lagged terms consistently. Monte Carlo studies are conducted to examine the finite sample performance of our approach, and an application of real data is also illustrated.