基因编辑技术背后的伦理与人权

当前基因编辑技术发展迅速,引起各国政府、学术界和企业界的广泛关注。但从近期“基因编辑婴儿”事件来看,基因编辑技术的伦理问题仍须厘清,我国现行法律尚不完善。通过保护基因编辑婴儿隐私、切实发挥伦理委员会作用、加快相关立法工作,我们或可更好地解决基因编辑技术背后的伦理和人权问题。     

“动物与人”：叙事伦理、悖反性与双重困境指向——论“抉择之痛”作为功能指涉的效力边际

对初始情境中受难者“陷困”功能的探讨，是“动物叙事”叙事语法研究中不容忽视的一环，其中贯穿了一个最为基础的叙事功能指向——“抉择之痛”。强调“动物与人”两类受难者角色在身体、心理抑或情感维度陷入某种矛盾与纠结的状态，并且彼此间时常呈现出一定的矛盾悖反性。这一角色身份由动物形象与人类形象分别或共同承担，均指向一种叙事伦理层面的现代境遇的表达。在题材范畴方面，这一功能指涉涵盖了家养类与野生类“动物叙事”各自的叙事范畴。其效力边际已不仅仅局限在单纯生态视域与人性指涉的层面，而是凸显现代语境下人类所面临的共通性的伦理困境：一种挥之不去的矛盾、困惑与不安的情感和心境的写照。     

The Ethical Foundations of Risk Analysis

In the field of risk analysis, the normative value systems underlying accepted methodology are rarely explicitly discussed. This perspective provides a critique of the various ethical frameworks that can be used in risk assessments and risk management decisions. The goal is to acknowledge philosophical weaknesses that should be considered and communicated in order to improve the public acceptance of the work of risk analysts.     

Recognizing Structural Nonidentifiability: When Experiments Do Not Provide Information About Important Parameters and Misleading Models Can Still Have Great Fit

In the quest to model various phenomena, the foundational importance of parameter identifiability to sound statistical modeling may be less well appreciated than goodness of fit. Identifiability concerns the quality of objective information in data to facilitate estimation of a parameter, while nonidentifiability means there are parameters in a model about which the data provide little or no information. In purely empirical models where parsimonious good fit is the chief concern, nonidentifiability (or parameter redundancy) implies overparameterization of the model. In contrast, nonidentifiability implies underinformativeness of available data in mechanistically derived models where parameters are interpreted as having strong practical meaning. This study explores illustrative examples of structural nonidentifiability and its implications using mechanistically derived models (for repeated presence/absence analyses and dose–response of Escherichia coli O157:H7 and norovirus) drawn from quantitative microbial risk assessment. Following algebraic proof of nonidentifiability in these examples, profile likelihood analysis and Bayesian Markov Chain Monte Carlo with uniform priors are illustrated as tools to help detect model parameters that are not strongly identifiable. It is shown that identifiability should be considered during experimental design and ethics approval to ensure generated data can yield strong objective information about all mechanistic parameters of interest. When Bayesian methods are applied to a nonidentifiable model, the subjective prior effectively fabricates information about any parameters about which the data carry no objective information. Finally, structural nonidentifiability can lead to spurious models that fit data well but can yield severely flawed inferences and predictions when they are interpreted or used inappropriately.     

我国幼儿教师职业道德研究回顾与前瞻——基于2009至2018年CNKI学术期刊论文的分析

采用文献计量学研究方法和主题内容分析法，回顾了2009至2018年我国幼儿教师职业道德研究的概貌，发现该领域文献研究的热点方向依次为：幼师师德失范与因应对策、幼师专业学生职业道德培养、幼师师德的规范建构与评价等。为进一步推动我国幼儿教师职业道德研究，关切该问题的学者可以形成研究共同体，从均衡研究维度着手，不断拓展研究视野的广度，并通过开展后续研究推进成果转化。     

美国师德问责体系的结构、特点及启示——基于德克萨斯州的经验

美国德克萨斯州历来重视教育工作者的职业道德建设，建立了一系列教育工作者违规行为问责机制，形成了较为完善的师德问责体系。美国德克萨斯州的师德问责体系具有独特的结构与特征。颁布《教育工作者伦理规范》，使问责有法可依；设立专门机构，使问责主体明确；细化教师违规行为，使问责有据可凭；强调证据证词，使问责合理科学；重视结果多样，使问责责罚分明。这些对于促进我国师德问责的规范化、制度化发展有着积极的借鉴意义。     

The Principles and Ethics of Including Children with Disability in Child Research

This paper provides a set of principles and ethics, developed in collaboration between Pacific‐ and Australian‐based researchers, to guide research practice in a project enabling the self‐reporting of children with disability in Vanuatu and Papua New Guinea (PNG). The paper presents both a summary of academic literature relating to these principles and ethics, as well as their succinct ‘translation’ into a set of action statements for researchers working with children with disability. The paper offers a base for further development by others to guide research practice and foster the autonomous participation of children with disability in developing countries.     

Autonomy,spontaneity and creativity in research with children. A study of experience and participation,in central Italy and North West England

ABSTRACT

Research involving children, deemed to have difficulties with conventional means of communication, can perpetuate reductive forms of representation of children’s knowledges and experiences. This article focuses on the possibilities and opportunities that visual and creative methods can offer to researching with children. Children advance their views in and through spontaneous and concrete forms of participation. Autonomy in aesthetic acts is central to this methodology; to explore practices that produce and reproduce presuppositions deriving from societal attitudes affecting research with children, their agency and self-presentation. This cross-cultural study was conducted in Central Italy and North West England: children contributed their perspectives and experiences through participation in a series of creative encounters resulting in aesthetic and embodied outcomes of sociological and educational significance. The study contributes to the debate on children’s autonomy and the value and quality of participation through artistic practice. Examples from the corpus of data, which includes a series of artefacts and over 900 photographs from each geo-cultural context, are presented. The study shows that it is possible to harmonise power imbalances in spaces of creative freedom, in research and education, where children’s choices and agency are respected.     

‘Making narrative portraits: a methodological approach to analysing qualitative data’

ABSTRACT

This paper proposes the method of ‘narrative portraiture’, which, located within the wider field of narrative studies, offers an analytical tool to narrative data. Two research projects, one on disability and one on identity, are used to illustrate how the method can be applied. While the paper will focus on the methodological benefits and limitations of the approach, throughout the article we also highlight the ethical concern of representation. We suggest that through ‘narrative portraiture’ research findings can be contextualised in broader social narratives without losing sight of the unique personal qualities of the research encounter. Thus, we argue for the importance of bringing the participant and their everyday life experience into focus, highlighting that a portrayal of a sole story can be, not only a medium to understand a research phenomenon, but also a valuable research output in itself.     

For the greater good? Ethical reflections on interviewing the ‘rich’ and ‘poor’ in qualitative research

ABSTRACT

There is increasing emphasis on understanding economic advantage alongside disadvantage – on studying both ‘poverty’ and ‘riches’. This trend prompts and requires new ethical reflection. I argue that in qualitative interview research, a clearer distinction needs to be drawn between ethical commitments to individual research participants, and the group(s) to which they belong. This distinction is often elided in ethics guidelines and when researchers discuss their own work. Attending to the distinction highlights a symmetrical ethical dilemma: researchers studying disadvantage are often motivated to further the interests of the wider group to which their participants belong, yet the study itself risks eliciting or exacerbating negative experiences or identities amongst participants themselves. Conversely, the process of studying advantage frequently bolsters the positive identities or experiences of individual study participants, even as the research findings challenge or subvert the interests of their group.