Learning from a lot: Empirical Bayes for high‐dimensional model‐based prediction

Empirical Bayes is a versatile approach to “learn from a lot” in two ways: first, from a large number of variables and, second, from a potentially large amount of prior information, for example, stored in public repositories. We review applications of a variety of empirical Bayes methods to several well‐known model‐based prediction methods, including penalized regression, linear discriminant analysis, and Bayesian models with sparse or dense priors. We discuss “formal” empirical Bayes methods that maximize the marginal likelihood but also more informal approaches based on other data summaries. We contrast empirical Bayes to cross‐validation and full Bayes and discuss hybrid approaches. To study the relation between the quality of an empirical Bayes estimator and p, the number of variables, we consider a simple empirical Bayes estimator in a linear model setting. We argue that empirical Bayes is particularly useful when the prior contains multiple parameters, which model a priori information on variables termed “co‐data”. In particular, we present two novel examples that allow for co‐data: first, a Bayesian spike‐and‐slab setting that facilitates inclusion of multiple co‐data sources and types and, second, a hybrid empirical Bayes–full Bayes ridge regression approach for estimation of the posterior predictive interval.     

面向21世纪“两课“教学总体研究

2 1世纪 ,复杂多变的国际国内形势 ,给“两课”教学带来前所未有的挑战。鉴于此 ,面向新世纪的“两课”教学总体研究势在必行。研究范围包括深化“两课”教学内容、完善课程体系、建全学科体系、改革教学方法、加强师资队伍建设等多个方面     

"信访权"之宪法定位

我国宪法并无信访权的规定,但一般认为,信访制度的宪法依据是宪法第41条,是公民宪法赋予的建议权、申诉权的具体体现。然而从实践和宪法权利理论出发,有必要对信访权加以分解,分为政治性权利和非政治性权利,从代议机构监督和制衡行政权的高度加强信访制度建设,推进我国宪政制度的完善。     

植物功能基因组学手段

综述了近几年发展起来的几种植物功能基因组学手段，对这些方法的优缺点作了比较．并讨论了植物功能基因组学的发展前景。     

深圳“九五”时期居民消费研究

以“九五”时期深圳居民生活消费统计数据为依据,从深圳居民的收入、支出水平入手,对深圳居民的消费水平、消费结构及变化特点进行分析,探讨“九五”时期深圳居民消费存在的主要问题。     

试论工科院校创新型人才培养的途径

从21世纪对创新型人才素质的需要出发,探讨了工科院校创新型人才培养的途径。强调应以更新传统教育观念,改革传统教育教学模式为根本,全面促进教育创新。应深入探索教学内容、教学方式和教学手段的改革,将新颖性、前沿性、综合性的教学内容引入课堂;应加速高校实验室的全面开放,以增加大学生参与科研实践的机会;通过开展大学生科技创新实践活动,创造有利于创新型人才培养的氛围;通过完善大学生的科技活动激励机制,以调动大学生主动进行科技探索和自觉培养创新意识的积极性。     

重庆民族地区旅游业的定位与发展取向

重庆民族地区具有完好的生态环境,丰富的自然旅游资源,深邃的古文化遗存,绚丽多姿的民族风情等旅游资源优势。21世纪,重庆民族地区旅游业的发展要突出旅游的文化内涵和知识性,坚持可持续发展思想,注意利用现代高新技术,重视旅游人才的培养,以民族文化为依托,开发多种形式的民族文化旅游项目。     

河北省高校周边文化圈建设研究

建设河北特色文化大省，实现文化大发展、大繁荣，是时代的课题。高校和地方文化各自独立发展，缺乏竞合的现状是制约河北文化发展的一个难题。高校周边文化圈建设是解决这一难题、建设文化特色大省的有效途径，河北省政府牵头，协调高校，以地方文化为主体，采取以点带面的形式，逐步实现文化圈的建设。     

100 key research questions for the post‐2015 development agenda

The Sustainable Development Goals (SDGs) herald a new phase for international development. This article presents the results of a consultative exercise to collaboratively identify 100 research questions of critical importance for the post‐2015 international development agenda. The final shortlist is grouped into nine thematic areas and was selected by 21 representatives of international and non‐governmental organisations and consultancies, and 14 academics with diverse disciplinary expertise from an initial pool of 704 questions submitted by 110 organisations based in 34 countries. The shortlist includes questions addressing long‐standing problems, new challenges and broader issues related to development policies, practices and institutions. Collectively, these questions are relevant for future development‐related research priorities of governmental and non‐governmental organisations worldwide and could act as focal points for transdisciplinary research collaborations.