你所不知道的普京

尽管他常常高调现身,但其形象依然模糊并难以捉摸。他在克格勃内的身份,他在前东德德累斯顿的工作经历从来都是一个谜,甚至他担任圣彼得堡市长助理时的活动,人们也都知之甚少。直到1996年8月,他到莫斯科赴任,仍有人将他贬损为一个平庸的角色。一名叶利钦时代的高官曾评价他是"一个庸才",是"叶利钦家族"的傀儡,追逐金钱的"克格勃恶棍"。也许所有这一切表象都是不准确的。事情的发展最终证明,他比十几年前几乎所有人所能认识到的那个人更加重要,也更     

Personal sacrifice and corporate cultures: career progression for disabled staff in higher education

Disabled people are under-represented in higher education (HE), especially in senior posts. This article reports research on the perspectives of career progression into leadership held by disabled staff in one post-1992 university. Findings indicated that some participants were already engaged in leadership or aspired to such roles, and reported positive experiences. However, participants also experienced barriers to progression, including a lack of awareness of equality and diversity among managers and colleagues, inadequate professional development opportunities and the competitive organisational culture of management that could impact on their health and work–life balance. We conclude that disabled staff in HE do not yet have equal opportunities for progression into leadership roles compared with their non-disabled peers. There is a need for realignment of the culture of leadership and management to make it more compatible with the full inclusion of disabled staff in HE such that their unique contributions are valued.     

Bioaccessibility and Risk of Exposure to Metals and SVOCs in Artificial Turf Field Fill Materials and Fibers

To reduce maintenance costs, municipalities and schools are starting to replace natural grass fields with a new generation synthetic turf. Unlike Astro‐Turf, which was first introduced in the 1960s, synthetic field turf provides more cushioning to athletes. Part of this cushioning comes from materials like crumb rubber infill, which is manufactured from recycled tires and may contain a variety of chemicals. The goal of this study was to evaluate potential exposures from playing on artificial turf fields and associated risks to trace metals, semi‐volatile organic compounds (SVOCs), and polycyclic aromatic hydrocarbons (PAHs) by examining typical artificial turf fibers (n = 8), different types of infill (n = 8), and samples from actual fields (n = 7). Three artificial biofluids were prepared, which included: lung, sweat, and digestive fluids. Artificial biofluids were hypothesized to yield a more representative estimation of dose than the levels obtained from total extraction methods. PAHs were routinely below the limit of detection across all three biofluids, precluding completion of a meaningful risk assessment. No SVOCs were identified at quantifiable levels in any extracts based on a match of their mass spectrum to compounds that are regulated in soil. The metals were measurable but at concentrations for which human health risk was estimated to be low. The study demonstrated that for the products and fields we tested, exposure to infill and artificial turf was generally considered de minimus, with the possible exception of lead for some fields and materials.     

The Value of Information in Decision‐Analytic Modeling for Malaria Vector Control in East Africa

Decision analysis tools and mathematical modeling are increasingly emphasized in malaria control programs worldwide to improve resource allocation and address ongoing challenges with sustainability. However, such tools require substantial scientific evidence, which is costly to acquire. The value of information (VOI) has been proposed as a metric for gauging the value of reduced model uncertainty. We apply this concept to an evidenced‐based Malaria Decision Analysis Support Tool (MDAST) designed for application in East Africa. In developing MDAST, substantial gaps in the scientific evidence base were identified regarding insecticide resistance in malaria vector control and the effectiveness of alternative mosquito control approaches, including larviciding. We identify four entomological parameters in the model (two for insecticide resistance and two for larviciding) that involve high levels of uncertainty and to which outputs in MDAST are sensitive. We estimate and compare a VOI for combinations of these parameters in evaluating three policy alternatives relative to a status quo policy. We find having perfect information on the uncertain parameters could improve program net benefits by up to 5–21%, with the highest VOI associated with jointly eliminating uncertainty about reproductive speed of malaria‐transmitting mosquitoes and initial efficacy of larviciding at reducing the emergence of new adult mosquitoes. Future research on parameter uncertainty in decision analysis of malaria control policy should investigate the VOI with respect to other aspects of malaria transmission (such as antimalarial resistance), the costs of reducing uncertainty in these parameters, and the extent to which imperfect information about these parameters can improve payoffs.     

Computing the log concave NPMLE for interval censored data

In analyzing interval censored data, a non-parametric estimator is often desired due to difficulties in assessing model fits. Because of this, the non-parametric maximum likelihood estimator (NPMLE) is often the default estimator. However, the estimates for values of interest of the survival function, such as the quantiles, have very large standard errors due to the jagged form of the estimator. By forcing the estimator to be constrained to the class of log concave functions, the estimator is ensured to have a smooth survival estimate which has much better operating characteristics than the unconstrained NPMLE, without needing to specify a parametric family or smoothing parameter. In this paper, we first prove that the likelihood can be maximized under a finite set of parameters under mild conditions, although the log likelihood function is not strictly concave. We then present an efficient algorithm for computing a local maximum of the likelihood function. Using our fast new algorithm, we present evidence from simulated current status data suggesting that the rate of convergence of the log-concave estimator is faster (between \(n^{2/5}\) and \(n^{1/2}\)) than the unconstrained NPMLE (between \(n^{1/3}\) and \(n^{1/2}\)).     

Two Pitfalls of Using Standard Regression Diagnostics When Both X and Y Have Measurement Error

Modern exploratory data analysis produces models that are not based on physical theory but that are consistent with pictures of the data. When both X and Y have error this can be risky, because important features are hidden. Two examples are given that show that systematic model departures and heteroscedasticity may not be detectable with standard regression diagnostics.     

Automatic selection of a linear predictor through frequency domain cross-validation

Given data from a weakly stationary stochastic process in discrete time, and any L-step ahead linear predictor estimated from that data, we will construct an approximately unbiased estimator of the resulting mean squared error of L-step ahead linear prediction. The motivation for the estimator is based on frequency domain cross-validation, and hence the range of validity and applicability of the resulting selection method is not limited by particular assumptions about the structure of the underlying stochastic process or the form of the fitted linear predictors. We also propose a new frequency domain predictor fitting method. The method provides a natural finite-past analog to the existing spectral factorization techniques, and it compares favorably with the existing techniques, both asymptotically and for finite samples. In a Monte Carlo study, we compare several predictor selection methods, at lead times one and five. The performance criterion used is the mean squared prediction error of the selected predictor. The new selection methods work well, and a comparison of results for the two different lead times underscores the need for tailoring the selection criterion to suit the lead time.