Matching Managers to Strategy: Further Tests of the Miles and Snow Typology

This paper integrates prior research on strategic leadership by building on the concept of alignment to explain the performance impact of top managers. Using the Miles and Snow (1978) typology as a theoretical framework, several hypotheses are tested on a sample drawn from three distinct industries. The results show that organizations that are able to achieve an alignment between managerial characteristics and strategic direction perform better than firms where such an alignment is absent. Further, it was found that the strategy-manager match explains a greater proportion of variance in performance than industry membership, organizational age and firm size. Taken together, these findings provide persuasive evidence about the impact that an organization's leaders exert in driving performance outcomes and demonstrates the validity of the administrative dimension of the Miles and Snow typology.     

A statistical framework for expression-based molecular classification in cancer

Summary. Genome-wide measurement of gene expression is a promising approach to the identification of subclasses of cancer that are currently not differentiable, but potentially biologically heterogeneous. This type of molecular classification gives hope for highly individualized and more effective prognosis and treatment of cancer. Statistically, the analysis of gene expression data from unclassified tumours is a complex hypothesis-generating activity, involving data exploration, modelling and expert elicitation. We propose a modelling framework that can be used to inform and organize the development of exploratory tools for classification. Our framework uses latent categories to provide both a statistical definition of differential expression and a precise, experiment-independent, definition of a molecular profile. It also generates natural similarity measures for traditional clustering and gives probabilistic statements about the assignment of tumours to molecular profiles.     

Risk and resilience factors for substance use among street adolescents: Assessment and development of an integrative model

In this study, risk and protective factors for substance use were explored to develop an intervention program and test its efficacy among male street‐based adolescents. Twenty expert interviews and key informant interviews were conducted. In addition, 30 street adolescents (15 substance‐users and 15 non‐users) participated in four focus group discussions for needs assessment, wherein risk and protective factors were discussed. Based on the identified needs, an intervention package was developed and validated by experts. The package was implemented in a natural environment of 50 street adolescents. After the intervention, about 60% of the respondents quit or cut down on their substance use substantially, and approximately 40% of the respondents agreed to reunite with their respective families, while 20% did not change their substance use habits. The results showed that if several protective factors were present, there was a lower risk of substance use. Many factors contribute to substance use and protective factors need to be strengthened in order to make interventions effective.     

Flexible reasoning using sensible agent-based systems: A case study in job flow scheduling

Planning and control systems for highly dynamic and uncertain manufacturing environments require adaptive flexibility and decision-making capabilities. Modern distributed manufacturing systems assess the utility of planning and executing solutions for both system goals (e.g. minimize manufacturing production time for all parts or minimize WIP) and local goals (e.g. expedite part A production schedule or maximize machine X utilization). Sensible Agents have the ability to alter their autonomy levels to choose among a set of decision models in order to handle the differences between local and system goals. In this paper, Sensible Agents are applied to a production planning and control problem in the context of job shop scheduling and decision model theory. Sensible Agents provide for trade-off reasoning mechanisms among system and local utilities that are flexible and responsive to an agent's abilities, situational context and position in the organizational structure of the system.     

Rural homelessness: its effect on healthcare access,healthcare outcomes,mobility, and perspectives of novel technologies

Rural homelessness is an undeniable public health issue that is understudied in the research literature. The purpose of this study was to determine the sociodemographics, physical and mental health status, barriers to access to care, and perspectives on potential technological advances of homeless individuals. A structured 45–90?min interview was utilized to gather demographic, physical health, mental health, mobility, and technology use data from a sample of 75 homeless individuals within three shelters in three micropolitan Nebraska cities. Individuals in this region were more likely to be white, unmarried, and mobile who have various physical and mental health disorders. Adherence to treatment of mental health disorders ranged from 43–60 percent. This population had increased employment, access to healthcare services, and use of technology than predicted. Leaders from all over the country can use these data to help improve state and local efforts to better cater to this vulnerable population's needs.     

The Role of Neighborhood Experiences in Psychological Distress Among African American and White Smokers

Race and Social Problems - Residential area characteristics and discrimination have been associated with psychological distress. Differences in these relationships across racial groups are not well...     

Characteristics of urban male homeless veterans and non-veterans in Omaha,Nebraska

The current study examined differences between urban homeless veterans and non-veterans on sociodemographics, housing, clinical characteristics, and psychosocial factors. We recruited a sample of 196 homeless men (101 veterans, 95 non-veterans) from the Omaha, Nebraska metropolitan area. Structured interviews were conducted by research staff. The results showed that the two groups were similar in most respects, though there were several notable differences. Homeless veterans were found to be older and more educated than non-veterans, more likely to have married, and reported having fewer non-adult children. Multivariable models controlling for age further showed that veterans reported a higher number of medical problems and were more likely to report being diagnosed with major depression or PTSD than non-veterans. Comparison with previous studies suggests changes in certain characteristics of homeless veterans over the past few decades that may reflect the growing proportion of veterans from the all-volunteer force, initiated after the draft ended in 1975. Findings from this study were consistent with previous comparative studies suggesting limited changes in recent decades in the characteristics of homeless veterans as compared to non-veterans, although the high prevalence of major depression and PTSD merit special treatment for these disorders.