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Federal and other regulatory agencies often use or claim to use a weight of evidence (WoE) approach in chemical evaluation. Their approaches to the use of WoE, however, differ significantly, rely heavily on subjective professional judgment, and merit improvement. We review uses of WoE approaches in key articles in the peer‐reviewed scientific literature, and find significant variations. We find that a hypothesis‐based WoE approach, developed by Lorenz Rhomberg et al., can provide a stronger scientific basis for chemical assessment while improving transparency and preserving the appropriate scope of professional judgment. Their approach, while still evolving, relies on the explicit specification of the hypothesized basis for using the information at hand to infer the ability of an agent to cause human health impacts or, more broadly, affect other endpoints of concern. We describe and endorse such a hypothesis‐based WoE approach to chemical evaluation.  相似文献   
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Why do some people and not others become involved in social movements? We examined the relationships between a moral emotion—disgust—and animal activism, attitudes toward animal welfare, and consumption of meat. Participants were recruited through two social networking websites and included animal activists, promoters of animal use, and participants not involved in animal-related causes. They took an online survey which included measures of sensitivity to visceral disgust, attitudes toward animal welfare, and frequency of meat eating. Animal activists were more sensitive to visceral disgust than were promoters of animal use or nonaligned participants. Disgust sensitivity was positively correlated with attitudes toward animal welfare but not with meat consumption. The relationship between animal activism and vegetarianism was complex; nearly half of animal activists ate meat, and half of the vegetarians did not consider themselves to be animal activists. We argue that conflicts over the moral status of animals reflect fundamental differences in moral intuitions.  相似文献   
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Court records from four Ohio counties were used to compare child support orders before and after promulgation of federally mandated guidelines in 1987. There was no significant change in probability of Court Ordered Child Support. Amount Ordered in constant dollars increased between 1985 and 1987–88. Variables influencing Court Ordered Child Support differed post-guidelines. Years Married, Attorney for Both and Attorney for Wife were significant in both years. Number of Children, Rural, and Wife's Motions were significant in 1987–88. Variables affecting amount ordered also differed after adoption of the guidelines. Wife Contested, Husband's Motions, Defendant and Plaintiff no longer were significant in 1987–88. Years Married and Payment by Father were significantly related to Amount Ordered in 1985 but not in 1987–88. Number of Children, Expenses Paid, and Number of Assets were significantly related to Amount Ordered in both years.Salaries and research support were provided by state and federal appropriations to the Ohio Agricultural Research and Development Center, and by the Department of Family Resource Management, and The Office of Research and Graduate Studies, The Ohio State University.Kathryn Stafford is Associate Professor, Department of Family Resource Management, 1787 Neil Avenue, Columbus, OH 43210-1295. Her research interests include household management and time use. She received her Ph.D. from Cornell University.Golden Jackson is Assistant Professor, Department of Family Resource Management, 1787 Neil Avenue, Columbus, OH 43210-1295. Her research is primarily in the area of the economic effects of divorce. She received her Ph.D. from The Ohio State University.Sharon Seiling is Assistant Professor and Extension Specialist in Family Resource Management, Department of Family Resource Management, 1787 Neil Avenue, Columbus, OH 43210-1295. Her research is on the impact of family change, especially divorce, on access to housing and overall financial well-being. She received her Ph.D. from Cornell University.  相似文献   
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This paper suggests that the concept of the muse in relation to the creative process is more than a myth or cultural artifact. It is argued that the muse is a psychic recollection of our memories of the female who presided over our first experiences of consciousness as we traversed the borders of inner and outer reality—that is, the mother. The shift of consciousness required in creative activity triggers recall of this figure. Object relations theory, recent findings from infant research, and the intuitive observations of several authors are used to support this thesis. Clinical examples illustrate the application of this concept in treatment.  相似文献   
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This research tests predictions regarding potential disparities among the employed by personal characteristics in the ability to vary the starting and ending times of their workday and engage in work from home. Women and African-Americans possess less access to flexible work schedules, even when controlling for most job characteristics. Married men have more access, but only if they are parents, and mothers only if they have pre-school-age children. Workers with part-time or long hours gain far greater access. Work-at-home is more common among women, the married and parents-thus, relatively more reflective of family demands. The results suggest where public and organizational policies could be focused to spread flexible work arrangements more toward those who both most value it and lack it.  相似文献   
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Books written for and about children may serve to convey central cultural tenets to new members of society. This paper looks at the depiction of encounters between newcomer and locally born children in contemporary Hebrew literature aimed at teenage readers and presents the major resources and practices by means of which the newcomer protagonists are portrayed as coming to find their place in the new society. The paper suggests that, rather than introducing Israeli‐born readers to newcomer cultures, as might be expected in the current ideological climate of cultural pluralism, these books serve as a means of conveying to children and young people socially sanctioned modes of coming to belong to Israeli society.  相似文献   
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Golden MA 《Omega》2010,62(1):31-49
A family member who is present when a loved one is dying in a hospital setting may be profoundly affected by interactions with others in that setting, including the dying person. Interaction shapes how one experiences a loved one's death and dying. Framed in relational dialectics theory, this qualitative case study describes dialectical contradictions I experienced in the context of my grandmother dying in a hospital setting. Personal journals were analyzed, with three primary dialectics being identified: certainty-uncertainty, control-lack of control, and autonomy-connection. Understanding dialectical contradictions experienced by a family member when a loved one is dying in a hospital setting could lead to enhanced support services for family members.  相似文献   
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This paper addresses needs of patients whom Winnicott called boring. Although often functioning well in the work world, they lack a rich inner life and a capacity for intimacy. Thus, psychotherapy is particularly problematic for them. To develop a model for working with this group of patients, the authors elaborate the concept of autistic barriers from British object relations theory, and suggest a changing role for the therapist in four successive phases of the treatment.  相似文献   
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