Pluralism and Universality of Environmental Discourse: The Dilemma Between Damage Caused by the Japanese Macaque and its Protection

Abstract:  The subject of this paper is to describe the complexity of relations between man and wild monkeys, which causes difficulties in forming a social consensus related to their conservation and management. To present how the relations are in everyday life, and how they are simplified in universal discursive spaces, interviews and a questionnaire survey have been conducted. As a result, it is clarified that there are three kinds of discursive spaces, that of politics, natural science, and residents. People who share the land with wild monkeys have various terms and stories about their relations with monkeys. The monkeys have various values in the discourse of residents, including many troubles. The existence of monkeys is vivid and close, and can be described as "accessible" nature. However, in discussion of politics or natural sciences, there is less diversity in monkeys' values. In these discursive spaces, monkeys are described simply in the framework of "distant" nature, and wild monkey issues are constructed as a "pest animal issue". The simplified protocol between accessible and distant nature makes the wild monkey issues simple. And the attitudes of residents are shown as controversial through the contradiction between simple-complex issues. In conclusion, this contradiction cannot be solved only by filling the gap between accessible and distant nature with social consensus, but also by connecting the two and enhancing the dynamism of society as a whole.     

Estimation of Benchmark Dose of Lifetime Cadmium Intake for Adverse Renal Effects Using Hybrid Approach in Inhabitants of an Environmentally Exposed River Basin in Japan

The aim of this study is to estimate the reference level of lifetime cadmium intake (LCd) as the benchmark doses (BMDs) and their 95% lower confidence limits (BMDLs) for various renal effects by applying a hybrid approach. The participants comprised 3,013 (1,362 men and 1,651 women) and 278 (129 men and 149 women) inhabitants of the Cd‐polluted and nonpolluted areas, respectively, in the environmentally exposed Kakehashi River basin. Glucose, protein, aminonitrogen, metallothionein, and β₂‐microglobulin in urine were measured as indicators of renal dysfunction. The BMD and BMDL that corresponded to an additional risk of 5% were calculated with background risk at zero exposure set at 5%. The obtained BMDLs of LCd were 3.7 g (glucose), 3.2 g (protein), 3.7 g (aminonitrogen), 1.7 g (metallothionein), and 1.8 g (β₂‐microglobulin) in men and 2.9 g (glucose), 2.5 g (protein), 2.0 g (aminonitrogen), 1.6 g (metallothionein), and 1.3 g (β₂‐microglobulin) in women. The lowest BMDL was 1.7 g (metallothionein) and 1.3 g (β₂‐microglobulin) in men and women, respectively. The lowest BMDL of LCd (1.3 g) was somewhat lower than the representative threshold LCd (2.0 g) calculated in the previous studies. The obtained BMDLs may contribute to further discussion on the health risk assessment of cadmium exposure.     

Finding environmentally important industry clusters: Multiway cut approach using nonnegative matrix factorization

This paper proposes an optimal combinatorial method for finding groups of industries with relatively large CO₂ emissions through industrial relations. Using an economic input–output table, we estimated a non-symmetric matrix describing how much CO₂ is emitted in producing the commodity of industry i, which was purchased to produce commodity of industry j, to meet the final demand for a specific commodity. A symmetric strength of relations matrix describing the CO₂ emissions associated with the industrial relations was further estimated using the non-symmetric matrix. The strength of relations matrix can be viewed as a representation of the supply-chain network of the final commodity. In this study, we estimated the strength of relations matrix associated with the final demand for automobiles and applied the multiway cut approach using nonnegative matrix factorization to the matrix in order to find environmentally important industry clusters in the Japanese automobile supply chain. According to our empirical results, the optimal number of industry clusters is 19, and 4 industry clusters are playing a key role in CO₂ emission reduction.     

The neyman accuracy and the wolfowitz accuracy of the stein type confidence interval for the disturbance variance

In this paper we consider the Neyman accuracy and the Wolfowitz accuracy of the Stein type improved confidence interval I?_S for the disturbance variance in a linear regression model. The Neyman accuracy is a measure related to the unbiasedness of a confidence interval, and the Wolfowitz accuracy is related to the closeness of the endpoints to the true parameter. We show that I?_S is not unbiased and give some numerical results for the Neyman accuracy. As for the Wolfowitz accuracy we derive the sufficient condition for I?_S to improve on the usual confidence interval under this criterion and show numerically that a large degree of improvement can be obtainted.     

Japanese urban sociology: Development and current trends

This article focuses on current trends in Japanese urban sociology as they developed historically. They can be understood in the distinctive context of Japanese sociology, as the products of an interaction between Western sociological theories and their adaptation to Japan’s own materials. The article begins with the historical context of urban development and provides an overview of the development of urban studies in Japan, including issues in the theory of urbanization, the distinctive character of the neighborhood association, Cbonaikai, and the formation of new local communities in suburban areas. The current trends since the 1980s involve the macro approach to urban restructuring, studies on urban ethnicity, and social network analysis. Overall, it is suggested that the influence of American sociology makes Japanese urban analysis comparative. I thank Claude S. Fischer and Tazuko Hanzawa for their help with editing this paper. Remain-ing deficiencies are mine.     

Novel concentration-QTc models for early clinical studies with parallel placebo controls: A simulation study

The QTc interval of the electrocardiogram is a pharmacodynamic biomarker for drug-induced cardiac toxicity. The ICH E14 guideline Questions and Answers offer a solution for evaluating a concentration-QTc relationship in early clinical studies as an alternative to conducting a thorough QT/QTc study. We focused on covariance structures of QTc intervals on the baseline day and dosing day (two-day covariance structure,) and proposed a two-day QTc model to analyze a concentration-QTc relationship for placebo-controlled parallel phase 1 single ascending dose studies. The proposed two-day QTc model is based on a constrained longitudinal data analysis model and a mixed effects model, thus allowing various variance components to capture the two-day covariance structure. We also propose a one-day QTc model for the situation where no baseline day or only a pre-dose baseline is available and models for multiple ascending dose studies where concentration and QTc intervals are available over multiple days. A simulation study shows that the proposed models control the false negative rate for positive drugs and have both higher accuracy and power for negative drugs than existing models in a variety of settings for the two-day covariance structure. The proposed models will promote early and accurate evaluation of the cardiac safety of new drugs.     

Clinical trial of treatment with saikokaryukotsuboreito for eugonadal patients with late-inset hypogonadism-related symptoms

The purpose of this study was to evaluate the efficacy and safety of saikokaryukotsuboreito (SKRBT), which is widely used for a variety of clinical conditions, neuropsychiatric disorders, for patients with LOH-related symptoms. Twenty-two eugonadal patients over 40 years of age with LOH-related symptoms were included in this study. SKRBT was given orally to these patients three times daily to a total of 7.5 g/day for more than two months. Laboratory and endocrinological profiles were reviewed, and LOH symptoms were judged by means of several health assessment instruments such as the Aging Males' Symptoms (AMS) scale, Self-rated Depression Scale (SDS), International Prostate Symptom Score (IPSS), and King's Health Questionnaire (KHQ). Total AMS scores and AMS subscores were significantly decreased after the treatment. The KHQ, general health perception and impact on life scores were also significantly decreased, although no significant improvement was observed in other KHQ factors or the SDS score or IPSS. The serum concentrations of testosterone fractions did not change with treatment. Laboratory values did not change, and no adverse effects were identified after treatment. We conclude that SKRBT may be considered for treatment of patients with LOH-related symptoms for eugonadal patients.     

明末“画本”的兴盛与市场

明末以后,有别于以往仅作为文字附属品的插图,以绘画为主体的纯画本开始大量刊行,我们可以看到《历代古人像赞》、《明状元图考》、《金陵图咏》、《唐诗画谱》等各个领域的画本实例。在中国, 插图本原被认为是通俗之作,多数书籍都仅以文字构成。因此,书籍中开始添加插图,后来甚至出现以绘画为主的书籍,这可说是中国书籍史上的一个大转变。这个转变确实可视为原本属于文人士大夫阶层的“雅”的书籍之通俗化。早期刊行的插图本,如元代的《全相平话》等,便是以通俗市场为取向的。然而,细察明末刊行的画本,则可见在当时版画技巧提升的背景下,出现了水平相当高的“雅”的作品。这些作品都锁定水平较高的读者市场而出版。但从另一个角度观察,在读者的定位上,相较于不借助绘画的帮助也能够鉴赏诗词的读者而言,《唐诗画谱》、《诗馀画谱》等可以说是较低层次的或以所谓中间层读者为取向的出版物。因此,对于明末的书籍市场而言,大众化(通俗化)与精英化(雅化)的两个层面都有考虑的必要。画本与此类在晚明出现的新兴读者有很密切的关系,两者之间是相辅相成的。     

Records of rat control campaigns in a food market with the largest seafood trading volume worldwide

Urban Ecosystems - Brown rats (Rattus norvegicus) and roof rats (Rattus rattus) are among the most common mammals worldwide. Little is known about the effects of season on rat population size,...