The Effect of Active and Passive Peer Discouragement on Adolescent Risk taking: An Experimental Study

This experiment investigated the effect of peer discouragement on adolescent risk taking. Overall, 269 Dutch adolescents aged 11–15 years completed a risk taking computer task in the presence of an e‐confederate who demonstrated very little risk taking (passive peer discouragement) and/or sent risk‐discouraging messages to participants (active peer discouragement). The results showed that, compared to a situation with no peer discouragement, adolescents took significantly less risk only when they encountered a combination of active and passive peer discouragement; hence, when peers practiced what they preached. No gender differences were found in the effect of passive and active peer discouragement on risk taking. The results showed that digital peer messages play a promising role in diminishing adolescent risk taking.     

Language and (in)securitization: Observations from educational research and practice in conflict‐affected contexts

Spurred in part by violent conflict and natural disaster, the surge in global migration calls for renewed attention to the central role of language in everyday (in)securitization. In this brief response, I draw on my work in the Middle East and among Arabic‐speaking populations in the United States to offer some illustration of the instantiation of global, macro‐processes of (in)securitization and surveillance in the everyday micro‐practices of schooling—issues that are possible to “see” when language policy is the site of inquiry. In centring everyday communicative practice, sociolinguistics provides a distinctive entry point for examining the lived experience of this (in)securitization, by illuminating pervasive and mundane micro‐processes within the “extraordinary” and routinized social interactions of everyday schooling.     

The Relations Between Parents' Smoking, General Parenting, Parental Smoking Communication, and Adolescents' Smoking

The present study examined whether the associations between general parenting practices (i.e., support, behavioral control, and psychological control) and parental smoking on the one hand and older and younger siblings' smoking on the other were mediated by parental smoking communication (i.e., frequency and quality of parent–adolescent communication concerning smoking-related issues). The focus of this paper was on examining whether these associations of parental actions and adolescents' smoking were different in older and younger siblings within the family. Participants were 428 Dutch families (mother, father, and their 2 adolescent siblings aged 13–17). The results of parent and adolescent reports indicated that general parenting practices and parental smoking were associated with parental smoking communication, which, in turn, was related with adolescent smoking. The magnitude of the associations between parenting and adolescent smoking did not differ between older and younger siblings. Supportive parents were generally more likely to engage in a high quality communication about smoking with their adolescent children; this was related to a lower likelihood to smoke. Parents who exerted psychological control were more likely to talk more frequently with their adolescents on smoking matters, which in turn, relates to a higher likelihood to smoke. Also, smoking parents were less likely to have high-quality parent–adolescent communication that relates to higher likelihoods to smoke. In general, the findings were similar across reporters. Implications for prevention are addressed.     

AIDE: Adaptive intrapatient dose escalation designs to accelerate Phase I clinical trials

Designing Phase I clinical trials is challenging when accrual is slow or sample size is limited. The corresponding key question is: how to efficiently and reliably identify the maximum tolerated dose (MTD) using a sample size as small as possible? We propose model-assisted and model-based designs with adaptive intrapatient dose escalation (AIDE) to address this challenge. AIDE is adaptive in that the decision of conducting intrapatient dose escalation depends on both the patient's individual safety data, as well as other enrolled patient's safety data. When both data indicate reasonable safety, a patient may perform intrapatient dose escalation, generating toxicity data at more than one dose. This strategy not only provides patients the opportunity to receive higher potentially more effective doses, but also enables efficient statistical learning of the dose-toxicity profile of the treatment, which dramatically reduces the required sample size. Simulation studies show that the proposed designs are safe, robust, and efficient to identify the MTD with a sample size that is substantially smaller than conventional interpatient dose escalation designs. Practical considerations are provided and R code for implementing AIDE is available upon request.