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1.
A novel method was used to incorporate in vivo host–pathogen dynamics into a new robust outbreak model for legionellosis. Dose‐response and time‐dose‐response (TDR) models were generated for Legionella longbeachae exposure to mice via the intratracheal route using a maximum likelihood estimation approach. The best‐fit TDR model was then incorporated into two L. pneumophila outbreak models: an outbreak that occurred at a spa in Japan, and one that occurred in a Melbourne aquarium. The best‐fit TDR from the murine dosing study was the beta‐Poisson with exponential‐reciprocal dependency model, which had a minimized deviance of 32.9. This model was tested against other incubation distributions in the Japan outbreak, and performed consistently well, with reported deviances ranging from 32 to 35. In the case of the Melbourne outbreak, the exponential model with exponential dependency was tested against non‐time‐dependent distributions to explore the performance of the time‐dependent model with the lowest number of parameters. This model reported low minimized deviances around 8 for the Weibull, gamma, and lognormal exposure distribution cases. This work shows that the incorporation of a time factor into outbreak distributions provides models with acceptable fits that can provide insight into the in vivo dynamics of the host‐pathogen system.  相似文献   
2.
Extending the works of scholars who have elucidated writing as the quintessential site for social transformation, the aim of this article is to locate the myriad possibilities for actualizing Donna Haraway's concept of cyborg writing in the field of organization studies. I contend that cyborg writing functions as a discursive mechanism by which to disrupt Enlightenment ideals of Cartesian duality, objectivity and rationality. These ideals inform the very structure of masculine privilege that emerge from having a society that is organized along androcentric values. Situating the scholarship of Jo Brewis, a contemporary scholar in the field, I illuminate how cyborg writing can be practised effectively, whereby greater richness is imparted into conceptualizations of, and theorizing on, organizational and management phenomena. I conclude with a discussion of the implications of cyborg writing, and with the identification of two trajectories that scholars can pursue in future studies. Progress along these two paths will move towards actualizing the feminist project for gender egalitarianism.  相似文献   
3.
A simple approximation for the doubly noncentral t-distribution, based upon the Fieller-Geary Theorem (1930) and approximate normality of the square root of the noncentral chi-square variable observed by Patnaik (1949), is developed, This approximation and an Edgeworth series expansion associated with it are evaluated. The simple approximation is seen to be reasonably accurate for most practical purposes.  相似文献   
4.
If the asymptotic normality of a statistic is inadequate for approximating its distribution in practice, then the statistic may be transformed in order to improve the approximation by accelerating the convergence to normality. We treat a goodness-of-fit statistic, the sum of the logarithms of generalized uniform spacings introduced by Cressie (1976, 1978), in this spirit. Specifically, we apply the method of maximum likelihood to simulations of the statistic in order to estimate a power transformation, as in Box & Cox (1964), and hence develop a small sample normal approximation. This approximation provides a more versatile method of applying the statistic than currently available tables of percentiles.  相似文献   
5.
In an age of transnational mobility, there has been a growing recognition of the need for both English and French mainstream classroom teachers to be trained to teach increasingly plurilingual student populations. In this article, I begin by describing the context for an exploratory comparative and collaborative ethnographic action research study in four English and French schools in Toronto, Canada and one school in Montpellier, France that engaged children as co-researchers of their lived plurilingualism. I analyse in particular the process of creating plurilingual multimodal books with students and teachers across the five different school cases. This paper focuses on the iterative ‘identity text’ creation process across all five schools by examining one plurilingual identity text from each case, along with students’ research conversations about their creative productions, and interviews with their classroom teachers and parents. Finally, I summarize five features of inclusive plurilingual pedagogy that emerged across the five cases and call for further collaborative research across English and French schools and scholarly communities investigating creative plurilingual language and literacy production in the twenty-first century.  相似文献   
6.
In this paper we present a class of ratio type estimators of the population mean and ratio in a finite population sample surveys with without replacement simple random sampling design, where information on an auxiliary variate x positively correlated with the main variate y is available. Large sample approximations to mean square errors (MSE) of these estimatorsare evaluated and their MSE's are compared with the MSE of the usual ratio estimator [ybar]R of [ybar] the population mean of y. It is shown that under certain conditions these estimators are more efficient than [ybar]R. When a prior knowledge of the value of thecoefficient of variation, cy, of y is at hand, ratio type estimator, say [ybar]1 of [ybar] is proposed. It is shown, under certain conditions, that [ybar]1 is more efficient than [ybar]R. When values of cy, cx and the population correlation coefficient ρ is at hand, then we have proposed another estimator, say [ybar]2 of [ybar], which is always better than [ybar]R as far as the efficiency is concerned. In fact, is [ybar] 2 is shown to be even better than [ybar]1. Finally estimators better than the usual ratio estimator [ybar]/[xbar] of [Ybar] are given.  相似文献   
7.
New bounds are obtained for the variance of the minimum variance unbiased estimator of p i n inverse sampling. A generalized procedure for further improving the bounds is also discussed.  相似文献   
8.
The partial least squares (PLS) approach first constructs new explanatory variables, known as factors (or components), which are linear combinations of available predictor variables. A small subset of these factors is then chosen and retained for prediction. We study the performance of PLS in estimating single-index models, especially when the predictor variables exhibit high collinearity. We show that PLS estimates are consistent up to a constant of proportionality. We present three simulation studies that compare the performance of PLS in estimating single-index models with that of sliced inverse regression (SIR). In the first two studies, we find that PLS performs better than SIR when collinearity exists. In the third study, we learn that PLS performs well even when there are multiple dependent variables, the link function is non-linear and the shape of the functional form is not known.  相似文献   
9.
The problem of estimation of parameters of a mixture of degenerate and exponential distributions is considered. A new sampling scheme is proposed and the exact bias and the mean square error (MSE) of the maximum likelihood estimators of the parameters is derived. Moment estimators, their approximate biases and the MSE are obtained. Asymptotic distributions of the estimators are also obtained for both the cases.  相似文献   
10.
Recursive estimates of a probability density function (pdf) are known. This paper presents recursive estimates of a derivative of any desired order of a pdf. Let f be a pdf on the real line and p?0 be any desired integer. Based on a random sample of size n from f, estimators f(p)n of f(p), the pth order derivatives of f, are exhibited. These estimators are of the form n?1∑nj=1δjp, where δjp depends only on p and the jth observation in the sample, and hence can be computed recursively as the sample size increases. These estimators are shown to be asymptotically unbiased, mean square consistent and strongly consistent, both at a point and uniformly on the real line. For pointwise properties, the conditions on f(p) have been weakened with a little stronger assumption on the kernel function.  相似文献   
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