The efficacy and safety of short-acting testosterone ointment (Glowmin) for late-onset hypogonadism in accordance with testosterone circadian rhythm

Introduction: It is well known that there is a reduction of circadian rhythm in blood testosterone levels with aging. Our previous report revealed that 3?mg of short-acting testosterone ointment (Glowmin: GL) elevated serum testosterone levels to within the physiological range for 4–6?h. The aim of this study was to clarify the clinical efficacy and safety of GL used topically once every morning, to enhance the circadian rhythm of testosterone, for late-onset hypogonadism (LOH).

Methods: A total of 61 LOH patients received 3?mg of GL topically once a day in the morning on scrotal skin for 24 weeks. The clinical efficacy of GL was evaluated by the aging males symptoms (AMS) scale, and blood sampling tests were measured before and after GL treatment.

Results: Mean patients age was 55.3?±?9.2 years old. Total AMS scores at 4, 12, and 24 weeks after GL treatments significantly decreased. The results of sub-analysis of AMS, including psychological, physical, and sexual factors also significantly improved after GL treatments. No severe adverse reactions or abnormal laboratory data were reported.

Conclusions: This study shows that TRT for LOH with once daily GL treatment supports testosterone circadian rhythm and should be considered to be an effective and safe therapy for LOH.     

Alternative Medicine and Herbal Use Among University Students

Abstract

Objective: This study sought to (1) examine perceived stress and resources to cope with stress as predictors of emotional eating during the transition to college and (2) determine whether body mass index (BMI) moderated the emotional eating-stress relationship. Participants: Participants were 97 college freshmen (73% female; BMI: M = 25.3 kg/m², SD = 5.7 kg/m²). Research was conducted in September 2012. Methods: Participants completed the Perceived Stress Scale, Emotional Eating Scale, and Eating and Appraisal Due to Emotions and Stress Questionnaire during the first month of college. Height and weight were measured objectively. Results: BMI moderated the relationship between perceived stress and emotional eating. Higher stress predicted greater emotional eating for the lower BMI groups, but not the highest group. Greater resources to cope with stress predicted lower emotional eating. Conclusions: Greater perceived stress and poorer resources to cope with stress may contribute to emotional eating during the transition to college. The relationship between perceived stress and emotional eating may vary by BMI.     

SOME REMARKS ON THE MEAN, MEDIAN, MODE AND SKEWNESS

Many sufficient conditions for inequalities about the mean, median, mode and skewness have been obtained. The paper presents a theorem that unifies already known results, gives some counter-examples, and considers the cases of Pearson distributions.     

Spatio-temporal distribution patterns of two tachinid flies,Epicampocera succincta andCompsilura concinnata parasitizingPieris

Summary Larvae of genusPieris in the northern part of Kyoto City are parasitized by two tachinid flies:Epicampocera succincta, a specialist on genusPieris, andCompsilura concinnata, a generalist with very wide host-range. We surveyed the parasitism rates ofPieris by both flies for two years at six study areas. In these study areas, there lived three host species in the genusPieris: P. rapae, P. melete, andP. napi, but neither tachinid parasitizedP. napi to any significant extent. In the mountainous district,P. rapae andP. melete coexisted and their populations were relatively continuous, while in the lowland, onlyP. rapae larvae were abundant in spring and autumn, but even they disappeared in summer. Parasitisms byE. succincta occurred mainly in mountainous district and never in the lowland.C. concinnata parasitizedPieris in all the areas, but its parasitisms occurred mainly in autumn. We analyzed the factors affecting the spatial and temporal patterns of parasitism rates and presumed that the temporal discontinuity of host population restricted the distribution of the specialist parasitoid.     

Play Theory of Delinquency: Toward a General Theory of “Action”

This article presents an exploratory conceptual framework for the understanding and analysis of the “play” quality of delinquency by reviewing urban ethnographies treating the relationship between group delinquency and play. An examination of interpretations of the causal mechanism of “action” shows that situation-specific definitions of the situation or “frames” rather than self-sustaining and autonomous (sub)cultural imperatives regulate the active pursuits of youths. This article argues that playlike deviance arises when there is a precarious balance between the playlike definitions of the situation and the definitions of the situation associated with the primary reality. Collective encouragement, intense involvement, and a challenge to reach the limit are mentioned as three elements of action that lead to fatal and irrevocable consequences.     

On Labor Policies Affecting Investment in General Human Capital

Abstract. This paper develops a search model including workers’ investments in general human capital and investigates the effects of labor policies such as subsidies to human capital investment and unemployment benefits on the accumulation of human capital. It is shown that the equilibrium is not optimal because workers underinvest in human capital or firms open too many vacancies in comparison with the number of unemployed workers. Comparative statics show that an increase in subsidies to human capital investment adds to the number of vacancies per unemployed worker and to workers’ investments in human capital and that an increase in unemployment benefits decreases them. Finally, labor policies that remove the distortion are explored.     

Disaster preparedness networks in rural Midwest communities: Organizational roles,collaborations, and support for older residents

ABSTRACT

This study investigated the roles and interconnections among community organizations belonging to local disaster coalitions in Midwest in supporting older residents. Representatives from 44 organizations participated in one-time survey. Most were non-profit (68%) or federal/state/local government agencies (23%). The analyses of 761 relationships showed stronger collaborations in assessment (average strength=2.88 on a 5-point scale), emergency response (2.72), and planning (2.61); and weaker collaborations in co-sponsoring programs (1.71) and supporting older residents (2.03). The extent of collaboration (network density) to support older adults was also low. Coalitions may enhance network density and centralization by developing sub-committee structure and strengthening existing collaborations.     

Selective Amnesia: Memory and History of the Urfalli Syrian Orthodox Christians

This article analyzes how a community of Syrian Orthodox Christians (Urfallis), who were forced to emigrate from Urfa to Aleppo in 1924, reconstruct their collective history. These displaced Christians maintain silence about two important events in their history. The reason for their emigration and their participation in the Syrian nationalist movement during the 1930s are either wiped from their memories or deliberately concealed. This selective amnesia is conditioned largely by the complex relationship between the ruling elite, whether French or Syrian, and ordinary Urfallis. The process of historical reconstruction suggests that the ambivalent position of these Christians, which stems from their religious affiliation and immigrant origin, makes them design alternative narratives in order to adapt to the changing political situation whilst they establish a secure position for themselves within Syrian society.