VOLUNTAS: International Journal of Voluntary and Nonprofit Organizations - While many scholars have postulated the decline of membership influence as an important consequence of the... 相似文献
A simple connected graph G with 2n vertices is said to be k-extendable for an integer k with \(0<k<n\) if G contains a perfect matching and every matching of cardinality k in G is a subset of some perfect matching. Lakhal and Litzler (Inf Process Lett 65(1):11–16, 1998) discovered a polynomial algorithm that decides whether a bipartite graph is k-extendable. For general graphs, however, it has been an open problem whether there exists a polynomial algorithm. The new result presented in this paper is that the extendability problem is co-NP-complete. 相似文献
For large cohort studies with rare outcomes, the nested case-control design only requires data collection of small subsets of the individuals at risk. These are typically randomly sampled at the observed event times and a weighted, stratified analysis takes over the role of the full cohort analysis. Motivated by observational studies on the impact of hospital-acquired infection on hospital stay outcome, we are interested in situations, where not necessarily the outcome is rare, but time-dependent exposure such as the occurrence of an adverse event or disease progression is. Using the counting process formulation of general nested case-control designs, we propose three sampling schemes where not all commonly observed outcomes need to be included in the analysis. Rather, inclusion probabilities may be time-dependent and may even depend on the past sampling and exposure history. A bootstrap analysis of a full cohort data set from hospital epidemiology allows us to investigate the practical utility of the proposed sampling schemes in comparison to a full cohort analysis and a too simple application of the nested case-control design, if the outcome is not rare.
The Anamnestic Comparative Self Assessment (ACSA) measure of subjective well-being (SWB) aims to reduce the problems of cultural
bias and relativity to external standards by allowing people to define the endpoints or ‘anchors’ of the measurement scale.
In medical terminology anamnestic denotes ‘based on memory’. The ACSA uses subjects’ memories of the best and worst periods
in their lives to define the anchors of the scale. They then assess their current quality of life relative to these personal
anchors. The South African pilot study tested the match between self-assessment of SWB with ACSA and the conventional single-item
measures of life satisfaction and happiness used in the South African Quality of Life Trends Study and analysed the narratives
of the best and worst times of life. The quota sample of 46 consisted of 26 residents of Makana district in the Eastern Cape
Province, South Africa, and 20 patients undergoing treatment in the local TB hospital. Mean SWB ratings with all three measures
of life satisfaction, happiness and ACSA were between 5 and 6 on a 0–10-point scale. Ratings on all three scales were positively
correlated. However, on ACSA the TB patients rated their current SWB 1.84 points lower than the community respondents, suggesting
a greater sensitivity of this measure. It was observed that the starting points of the life stories produced by respondents
to define the anchor periods for ACSA were related to their current assessment of SWB. A typology was developed that combined
the starting point of the life stories with current SWB. The majority of community respondents matched the ‘Achiever’ type
who scored positively on ACSA (i.e., above the mid-point of the scale) and whose life stories started with the worst period
of their lives and proceeded to the best period. The TB patients were the only respondents to represent the ‘Survivor’ type
whose morale had recovered after misfortune in life. ‘Survivors’ started their narratives with the best period in their lives,
then moved to the worst (often health-related) one, and gave positive ACSA ratings. Based on the qualitative analysis of narratives,
it is concluded that ACSA is a sensitive measurement instrument and therefore particularly useful for monitoring the effects
of treatments and social interventions in longitudinal studies. However, further research is required to verify its cross-cultural
validity.
City managers and urban sociologists traditionally viewed ethnic places as undesirable areas of overcrowding and social pathology. Regarded as either transitional districts or obstacles to modernization, ethnic places were subject to slum clearance during the modernist phase of urban development. Ethnic places have acquired a new historical and sentimental salience in the "postmodern" developmental era. Preservationist activists and minority "place entrepreneurs" project ethnic culture and symbolic representations in defensive or proactive ways to stimulate neighborhood revitalization. These trends are evident in the recent urban developmental history of Houston, Texas. 相似文献
We re-evaluate Andreu and Spanos's findings in favour of trend stationarity by considering the extended Nelson-Plosser data set. This expanded (to 1988) data set includes a period of rather different behaviour compared with the original Nelson-Plosser data used by Andreou and Spanos. We find that Andreou and Spanos's models (with only minor adjustments) exhibit remarable stability over this extended period, and indicate that their conclusions are more robust than they have shown. 相似文献
A mechanistic model is presented describing the clearance of a compound in a precision-cut liver slice that is incubated in a culture medium. The problem of estimating metabolic rate constants in PBPK models from liver slice experiments is discussed using identifiability analysis. From the identifiability problem analysis, it appears that in addition to the clearance, the compound's free fraction in the slice and the diffusion rate of the exchange of the compound between culture medium and liver slice should be identified. In addition, knowledge of the culture medium volume, the slice volume, the compound's free fraction, and octanol-water-based partition between medium and slice is presupposed. The formal solution for identification is discussed from the perspective of experimental practice. A formally necessary condition for identification is the sampling of parent compound in liver slice or culture medium. However, due to experimental limitations and errors, sampling the parent compound in the slice together with additional sampling of metabolite pooled from the medium and the slice is required for identification in practice. Moreover, it appears that identification results are unreliable when the value of the intrinsic clearance exceeds the value of the diffusion coefficient, a condition to be verified a posteriori. 相似文献
The development of a Municipal Information System, or currently better known as a local spatial data infrastructure, is considered complex due to the required inter-institutional relationships. In many developing countries Geographical Information Systems (GISs) are introduced but the benefits are modest as no changes take place in technical and organisational structure of organisations. Digital databases and computer-aided design (CAD) maps are mushrooming in great variety within different private and public institutions, municipal organisations and even within single departments and with structures similar to the paper period and thus operating on a stand-alone basis.Many national mapping agencies are not able to provide large-scale digital urban base maps, while the absence or low quality of cadastres makes those basic core data sets unavailable or inaccessible. The result is that duplication and incompatible data are frequently observed and also donor-driven stand-alone projects have a limited impact through the lack of institutional embedding and are not able to mature from the project to the institutional level. However, a positive sign is that there is an increasing awareness among data producers and consumers that investments in the development of digital data sets should be combined to reduce costs and increase benefits from especially GIS, and information and communication technology (ICT) in general.Within Trujillo a long-term vision was developed to make full use of ICT and GIS to modernise all operations of the Municipality to increase the efficiency and effectiveness of its tasks. However, large investments are not feasible due to the very limited municipal budgets. To guarantee the support of the municipal council, short-term results are required. This paper describes three ‘products’ as part of the vision to develop through a step-by-step approach a local spatial data infrastructure for Trujillo.The three, rather different, products are:
1. fiscal cadastre, to increase municipal revenues through property taxation;
2. an ‘environmental atlas’ based on a compatible spatial and attribute data sets from a variety of organisations; and
3. a municipal website with interactive GIS and meta data information.
The paper concludes with some comments on the institutional and political requirements for the successful development of a local spatial data infrastructure and stresses that such an infrastructure is not a product but an incremental development process that will progress only in case such a process is simple, cost effective, user-friendly, and flexible with clear products.Political interest and institutional stability and genuine interest for inter-institutional cooperation will add much to the success of this process. 相似文献