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1.
Review of Economics of the Household - Tax benefits targeted to low-wage workers have become very common transfer programs that seek to meet both efficiency and equity targets. An expanding... 相似文献
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Exact calculation of power and sample size in bioequivalence studies using two one‐sided tests 下载免费PDF全文
The number of subjects in a pharmacokinetic two‐period two‐treatment crossover bioequivalence study is typically small, most often less than 60. The most common approach to testing for bioequivalence is the two one‐sided tests procedure. No explicit mathematical formula for the power function in the context of the two one‐sided tests procedure exists in the statistical literature, although the exact power based on Owen's special case of bivariate noncentral t‐distribution has been tabulated and graphed. Several approximations have previously been published for the probability of rejection in the two one‐sided tests procedure for crossover bioequivalence studies. These approximations and associated sample size formulas are reviewed in this article and compared for various parameter combinations with exact power formulas derived here, which are computed analytically as univariate integrals and which have been validated by Monte Carlo simulations. The exact formulas for power and sample size are shown to improve markedly in realistic parameter settings over the previous approximations. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
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Letter to the editor by the authors of Exact Calculation of Power and Sample Size in Bioequivalence Studies Using Two One‐sided Tests,Pharmaceutical Statistics,DOI: 10.1002/pst.1666 下载免费PDF全文
This article reflects the views of the authors and should not be construed to be those of the US Food and Drug Administration. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
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Nir Cohen Daniel Czamanski Amir Hefetz 《International migration (Geneva, Switzerland)》2015,53(6):74-88
Recent scholarship emphasizes differences among ethnic groups' internal migration patterns. Yet, with few exceptions, research has focused on the Anglo‐American world, neglecting experiences from other regions. This paper is part of a larger research project that studies mobility among the Arab minority in Israel and its driving forces. In this paper we examine patterns of internal migration by analysing the propensity to migrate as well as migrants' individual and social characteristics. First, we survey the theoretical backdrop that is suggested by recent geographic literature on internal migration among ethnic and racial minorities, including native groups. Second, we contextualize the group studied, providing necessary background information on the political, socio‐economic and demographic conditions of Arabs in Israel. We briefly discuss attributes that are – or have been – potential hindering factors to Arab mobility in the Jewish state. Finally, we analyse 1995 national census data at the micro scale and provide a basis for future explanations of the phenomenon. We conclude by outlying some future directions in the study of internal migration of minorities in Israel. 相似文献
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Examining the Interplay of Career,Migration and National Cultural Identity: The Case of Indian Scientists 下载免费PDF全文
Laurie Cohen Joanne Duberley M.N. Ravishankar 《International migration (Geneva, Switzerland)》2015,53(5):104-121
In this paper, we examine individuals’ career migration across international borders. It is widely recognized that globalization has fundamental implications for the careers of people across geographical and cultural boundaries. However, our understanding of the interplay of migration, career development and national/cultural identities remains undeveloped within the extant literature. In this paper, we seek to offer insights into this relationship. Focusing on Indian scientists, an occupational group whose careers have long been associated with movement around the world, in this paper we examine these issues. Empirically, we examine three themes: why Indian scientists see international mobility as important in the development of their careers; continued links with India; and the interplay of national/cultural affiliation and respondents’ career experiences. In light of our findings, in the discussion section we argue that considering Indian scientists as a career diaspora highlights three important features that in the main have received only limited attention in the extant literature: career as a social form and process; the notion of the scientific career as a cultural product; and the interrelationship of career and national/cultural affiliation as ongoing facets of individuals’ identities as they develop diasporic careers. 相似文献
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María Isabel Ayala 《Sociological Forum》2012,27(4):1037-1045
In this essay, I present an interdisciplinary examination of the state of research in Latino education, addressing not only the cultural forces influencing Latinos’ educational attainment, but also the structural conditions faced by them—as a racialized minority group—throughout their schooling and that have a cumulative effect on their academic attainment. Overall, I suggest that by engaging in a critical review of the literature on Latinos’ educational attainment, the reader will acknowledge that the racially driven hierarchical structural arrangements are highly responsible for the patterns observed. 相似文献
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Research linking childhood physical abuse (CPA) and adult intimate partner aggression (IPA) has focused on individuals without sufficient attention to couple processes. In this study, 109 couples reported on histories of CPA, IPA, and anger expression. Actor-partner interdependence model (APIM) was used to examine links between CPA and revictimization and perpetration of IPA, with anger suppression as a potential mediator. Women's CPA histories were associated with more physical aggression towards and more revictimization by partners. Men's CPA histories were only associated at the trend level with their revictimization. Anger suppression fully mediated the link between women's CPA and both revictimization and perpetration of IPA. Findings suggest that women with CPA histories are more prone to suppress anger, which leaves them at greater risk for revictimization and perpetration of IPA. 相似文献
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Reuven Cohen Mira Gonen Asaf Levin Shmuel Onn 《Journal of Combinatorial Optimization》2017,33(2):645-659
In this paper we define the exact k-coverage problem, and study it for the special cases of intervals and circular-arcs. Given a set system consisting of a ground set of n points with integer demands \(\{d_0,\dots ,d_{n-1}\}\) and integer rewards, subsets of points, and an integer k, select up to k subsets such that the sum of rewards of the covered points is maximized, where point i is covered if exactly \(d_i\) subsets containing it are selected. Here we study this problem and some related optimization problems. We prove that the exact k-coverage problem with unbounded demands is NP-hard even for intervals on the real line and unit rewards. Our NP-hardness proof uses instances where some of the natural parameters of the problem are unbounded (each of these parameters is linear in the number of points). We show that this property is essential, as if we restrict (at least) one of these parameters to be a constant, then the problem is polynomial time solvable. Our polynomial time algorithms are given for various generalizations of the problem (in the setting where one of the parameters is a constant). 相似文献