Parametric Modeling for Survival with Competing Risks and Masked Failure Causes

We consider a life testing situation in which systems are subject to failure from independent competing risks. Following a failure, immediate (stage-1) procedures are used in an attempt to reach a definitive diagnosis. If these procedures fail to result in a diagnosis, this phenomenon is called masking. Stage-2 procedures, such as failure analysis or autopsy, provide definitive diagnosis for a sample of the masked cases. We show how stage-1 and stage-2 information can be combined to provide statistical inference about (a) survival functions of the individual risks, (b) the proportions of failures associated with individual risks and (c) probability, for a specified masked case, that each of the masked competing risks is responsible for the failure. Our development is based on parametric distributional assumptions and the special case for which the failure times for the competing risks have a Weibull distribution is discussed in detail.     

Accountability and academic freedom: The battle concerning research on cold fusion at Texas A&M university

abstract

The Massachusetts Task Force on Human Subject Research has so far been the only serious attempt to investigate radiation experiments on humans. No other federal, state or private agency has looked at a specific experiment in detail. The President's Advisory Committee on Human Radiation Experiments (ACHRE) provided an overview of the entire nationwide research project, but without a thorough evaluation of any single experiment. The Massachusetts Task Force examined a group of experiments using institutionalized children at two state facilities, the Fernald and Wrentham schools, from 1943 to 1973. The experiments were performed under supervision by scientists at Harvard and MIT, and were funded by several federal agencies. The Task Force found that these experiments were conducted according to the ethical and protocol standard of their day. This did not prevent the Task Force from judging that the experiments violated human rights, and recommending apology and compensation to the victims.     

先锋小说中的词语超常搭配现象探微

先锋小说是20世纪80年代的一个重要的文学现象。以先锋小说中的词语超常搭配现象为研究对象，初步分析了先锋小说中的词语超常搭配在主谓结构、偏正结构、动宾结构、并列结构这四种句法结构中的体现，从而从一个侧面展现出先锋小说语言实验的特点。     

在高校物理实验中引入计算机辅助

论述了在物理实验中引入计算机辅助的构思和必要性，列举了计算机在辅助教学（CAI）、模拟实验等方面的应用。     

On aliasing and generalized defining relationships of factorial arrangements

The concepts of defining contrast (DC), generalized defining relationship (GDR) and aliasing structure (AS) are now well established in the terminology of regression analysis and factorial design theory. There is no complete agreement in the literature about the meaning of regular and irregular fractional factorial designs. This paper provides a workable definition of a regular fraction from a symmetrial prime-powered factorial. It characterizes the uniqueness of the GDR for fractions from the most general factorial. Results are also présentés on the uniqueness of the GDR for regular designs, on orthogonality aspects of regular and irregular designs, and on group-theoretic generation of the complete aliasing structure. Examples are provided to illustrate the developments.     

Experimental Coastal Land Reclamation: Qianhai as a Case Interpreted

ABSTRACT

Informed by a Coasian transaction cost paradigm enriched by the concept of Schumpeterian innovations, this paper discusses the advantages of using experimental coastal reclamation of the sea to build new cities with a policy for fostering innovations. A new development area at the margin of Shenzhen in China, Qianhai, is used to demonstrate how urban expansion by urban sprawling in a megacity can be avoided by reclamation of marginal land as analytically less costly than along intra-marginal land and more suitable for experimentation for the type of megacity concept that Qianhai aims to achieve.     

The red and the black: China’s social credit experiment as a total test environment

China's social credit system is an unusually explicit case where technology is used by multiple actors to turn human behavior into a test object on behalf of the state's goal of modifying the larger social environment, making it an intriguing setting for thinking about the new sociology of testing. This article considers how China's search for a usable “credit” score to both allocate financial resources and explicitly measure a citizen's trustworthiness creates an emergent experimental system of governance similar to, yet not quite captured by, the kinds of experimental processes observed in literature on the platform as a form of market-based governance. As a site where “seeing like a state” and “seeing like a market” converge, the social credit system is a vantage point for observing the changing relationship between moral and economic domains in an era of digital platforms. The article highlights the experimental quality of the system and its emerging system of governance structured around reward and punishment and argues that strategic ambiguity, institutionalized through the affordances of digital platforms, is an important part of the design of this large-scale social experiment.     

Grandchildren Caring for Grandparents: Modeling the Complexity of Family Caregiving

ABSTRACT

This study focuses on grandchildren (Generation 3 or G3) caring for grandparents (Generation 1 or G1) and uses agent-based modeling to conceptualize and test a model of two factors—capability and motivation—that may affect a G3's decision to provide care for a G1. We tested our conceptual model and found that the simulated proportion of G3 caregivers has concurrent validity with existing empirical data. In experiments conducted with the validated model, we investigated universal- and targeted-policy changes (tax credit for caregivers) and found that although the universal-policy change increased G3 caregiving overall, a policy change targeting low- and middle-income caregivers was even more successful.     

The toxicology report audit

In a study of volunteers in medical research we found contrasting readings of “being comfortable” by the volunteer research subjects and the researchers. Although the experimental process (testing a new kind of diagnostic technology) involved some physical discomfort—and the researchers focused on this—the volunteers’ concerns centred on feeling socially comfortable and managing feelings of embarrassment or isolation, and they generally made light of the physical aspects. The bias of volunteer concerns, which is understandable in terms of the different situations of researchers and volunteers and the different tensions they create, has potential implications for the engagement of researchers with their research subjects and prevailing standards for the ethical and accountable conduct of research.