The Incremental Group Testing Model for Gap Closing in Sequencing Long Molecules |
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Authors: | Frank K. Hwang Wen-Dar Lin |
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Affiliation: | (1) Department of Applied Mathematics, National Chiao Tung University, HsinChu, 30050, Taiwan, Republic of China;(2) Institute of Information Science, Academia Sinica, 128, Academia Road, Sec. 2, Taipei, Taiwan, 115 |
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Abstract: | In this paper, we propose the incremental group testing model for the gap closing problem, which assumes that we can tell the difference between the outcome of testing a subset S, and the outcome of testing S {x}. We also give improvements over currently best results in literature for some other models. |
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Keywords: | contig sequencing gap closing group testing multiplex PCR detecting matrix separating matrix affine plane method |
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