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The Incremental Group Testing Model for Gap Closing in Sequencing Long Molecules
Authors:Frank K. Hwang  Wen-Dar Lin
Affiliation:(1) Department of Applied Mathematics, National Chiao Tung University, HsinChu, 30050, Taiwan, Republic of China;(2) Institute of Information Science, Academia Sinica, 128, Academia Road, Sec. 2, Taipei, Taiwan, 115
Abstract:
In this paper, we propose the incremental group testing model for the gap closing problem, which assumes that we can tell the difference between the outcome of testing a subset S, and the outcome of testing S cup {x}. We also give improvements over currently best results in literature for some other models.
Keywords:contig sequencing  gap closing  group testing  multiplex PCR  detecting matrix  separating matrix  affine plane method
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