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Institutional Pathology and the Death of Dan Markingson
Authors:Carl Elliott
Affiliation:Center for Bioethics, University of Minnesota, Minneapolis, Minnesota, USA
Abstract:
In the spring of 2015, 11 years after a mentally ill young man named Dan Markingson stabbed himself to death in an industry-sponsored drug study, officials at the University of Minnesota suspended recruitment of subjects into drug trials in its Department of Psychiatry. University officials agreed to act only after a scathing investigation by Minnesota Office of the Legislative Auditor found damning evidence of coerced recruitment, inadequate clinical care, superficial research oversight, a web of serious, disturbing conflicts of interest, and a pattern of misleading public statements by university officials aimed at deflecting scrutiny. In this article, I examine the larger institutional factors leading up to Markingson’s suicide and prevented corrective action for so long.
Keywords:Conflict of interest  human subjects ethics  human subjects regulation and oversight  informed consent  misconduct in research  organizational and institutional ethics  research ethics  research ethics in university contexts  research on the mentally ill  vulnerable populations
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