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A new response-adaptive design for continuous treatment responses for phase III clinical trials |
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| Authors: | Uttam Bandyopadhyay Rahul Bhattacharya |
| Institution: | a Department of Statistics, University of Calcutta, 35 Ballygunge Circular Road, Kolkata 700 019, India b Applied Statistics Unit, Indian Statistical Institute, 203 B.T. Road, Kolkata 700 108, India c Department of Statistics, West Bengal State University, Barasat, Kolkata 700 126, India |
| Abstract: | A new response-adaptive design, applicable for general class of continuous response distributions, is proposed. The allocation design is studied both theoretically and numerically and compared with some existing procedures. The applicability of the proposed procedure is also illustrated using real life data sets. |
| Keywords: | Ethics Optimality Response adaptive procedure |
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