Association between dietary phytoestrogens intakes and prostate cancer risk in Sicily |
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| Authors: | Giorgio I Russo Marina Di Mauro Federica Regis Giulio Reale Daniele Campisi Marina Marranzano |
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| Institution: | 1. Urology Section, University of Catania, Catania, Italy;2. Department of Medical and Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, Section of Hygiene and Preventive Medicine, University of Catania, Catania, Italy |
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| Abstract: | Objective: In this study we aimed to investigate the association between dietary phytoestrogen consumption and prostate cancer in a sample of southern Italian individuals.Methods: A population-based case-control study on the association between prostate cancer and dietary factors was conducted from January 2015 to December 2016 in a single institution of the municipality of Catania, southern Italy (Registration number: 41/2015). A total of 118 histopathological-verified prostate cancer (PCa) cases and a total of 222 controls were collected. Dietary data was collected by using two food frequency questionnaires.Results: Patients with PCa consumed significantly higher levels of phytoestrogens. Multivariate logistic regression showed that lignans (Qquartile]4 vs. Q1, OR odds ratio]?=?4.72; p?p?p?p?p?p?p?Conclusion: We found of an inverse association between dietary isoflavone intake and PCa, while a positive association was found with lignans intake. |
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| Keywords: | Phytoestrogens prostate cancer risk factors diet Mediterranean diet |
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