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A Weighting Approach for GEE Analysis with Missing Data
Authors:Cuiling Wang  Myunghee Cho Paik
Affiliation:1. Department of Epidemiology and Population Health , Albert Einstein College of Medicine , Bronx , New York , USA cuiling.wang@einstein.yu.edu;3. Department of Biostatistics , Columbia University , New York , New York , USA
Abstract:
We propose a new weighting (WT) method to handle missing categorical outcomes in longitudinal data analysis using generalized estimating equations (GEE). The proposed WT provides a valid GEE estimator when the data are missing at random (MAR), and has more stable weights and shows advantage in efficiency compared to the inverse probability weighing method in the presence of small observation probabilities. The WT estimator is similar to the stabilized weighting (SWT) estimator under mild conditions, but it is more stable and efficient than SWT when the associations of the outcome with the observation probabilities and the covariate are strong.
Keywords:Generalized estimating equation (GEE)  Imputation  Inverse probability weighting (IPW)  Longitudinal studies  Missing at random (MAR)  Stabilized weighting
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