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A Generalized Log-Normal Model for Grouped Survival Data
Authors:Liciana V. A. Silveira  Enrico A. Colosimo  José Raimundo de S. Passos
Affiliation:1. Departamento de Bioestatística, IB/UNESP , Botucatu, SP, Brazil liciana@ibb.unesp.br;3. Departamento de Estatística, ICEx/UFMG , Belo Horizonte-MG, Brazil;4. Departamento de Bioestatística, IB/UNESP , Botucatu, SP, Brazil
Abstract:
It is common to have experiments in which it is not possible to observe the exact lifetimes but only the interval where they occur. This sort of data presents a high number of ties and it is called grouped or interval-censored survival data. Regression methods for grouped data are available in the statistical literature. The regression structure considers modeling the probability of a subject's survival past a visit time conditional on his survival at the previous visit. Two approaches are presented: assuming that lifetimes come from (1) a continuous proportional hazards model and (2) a logistic model. However, there may be situations in which none of the models are adequate for a particular data set. This article proposes the generalized log-normal model as an alternative model for discrete survival data. This model was introduced by Chen (1995 Chen , G. ( 1995 ). Generalized Log-normal distributions with reliability application . Comput. Stat. Data Anal. 19 : 300 – 319 . [Google Scholar]) and it is extended in this article for grouped survival data. A real example related to a Chagas disease illustrates the proposed model.
Keywords:Discrete models  Interval censoring  Logistic model  Proportional hazards model
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