Asymptotic properties of mean survival estimate based on the Kaplan-Meier curve with an extrapolated tail |
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| Authors: | Gong Qi Fang Liang |
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| Affiliation: | Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA. |
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| Abstract: | Asymptotic distribution of the mean survival time based on the Kaplan-Meier curve with an extrapolated 'tail' is derived. A closed formula of the variance estimate is provided. Asymptotic properties of the estimator were studied in a simulation study, which showed that this estimator was unbiased with proper coverage probability and followed a normal distribution. An example is used to demonstrate the application of this estimator. |
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| Keywords: | mean survival restricted mean survival extrapolation variance estimate quality‐adjusted lifetime |
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