| Abstract: | Although most models for incomplete longitudinal data are formulated within the selection model framework, pattern-mixture models have gained considerable interest in recent years R.J.A. Little, Pattern-mixture models for multivariate incomplete data, J. Am. Stat. Assoc. 88 (1993), pp. 125–134; R.J.A. Lrittle, A class of pattern-mixture models for normal incomplete data, Biometrika 81 (1994), pp. 471–483], since it is often argued that selection models, although many are identifiable, should be approached with caution, especially in the context of MNAR models R.J. Glynn, N.M. Laird, and D.B. Rubin, Selection modeling versus mixture modeling with nonignorable nonresponse, in Drawing Inferences from Self-selected Samples, H. Wainer, ed., Springer-Verlag, New York, 1986, pp. 115–142]. In this paper, the focus is on several strategies to fit pattern-mixture models for non-monotone categorical outcomes. The issue of under-identification in pattern-mixture models is addressed through identifying restrictions. Attention will be given to the derivation of the marginal covariate effect in pattern-mixture models for non-monotone categorical data, which is less straightforward than in the case of linear models for continuous data. The techniques developed will be used to analyse data from a clinical study in psychiatry. |
