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Some practical issues of adaptive GPU design
Authors:Ao Yuan
Affiliation:Howard University, Washington, DC, USA
Abstract:We study some practical applications in clinical trial of the adaptive optimal generalized Pólya urn (GPU) design we recently proposed. We considered some common cases in clinical trial: delayed response, staggered/censored entry, heterogeneity and longitudinal/repeated observation. Asymptotic properties of these designs are studied.
Keywords:Generalized Pó  lya urn design   Delayed response   Staggered/censored entry   Heterogeneity   Longitudinal/repeated observation
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