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Computing the log concave NPMLE for interval censored data
Authors:Clifford Anderson-Bergman  Yaming Yu
Affiliation:1.Department of Statistics,UC Berkeley,Berkeley,USA;2.Department of Statistics,UC Irvine,Irvine,USA
Abstract:In analyzing interval censored data, a non-parametric estimator is often desired due to difficulties in assessing model fits. Because of this, the non-parametric maximum likelihood estimator (NPMLE) is often the default estimator. However, the estimates for values of interest of the survival function, such as the quantiles, have very large standard errors due to the jagged form of the estimator. By forcing the estimator to be constrained to the class of log concave functions, the estimator is ensured to have a smooth survival estimate which has much better operating characteristics than the unconstrained NPMLE, without needing to specify a parametric family or smoothing parameter. In this paper, we first prove that the likelihood can be maximized under a finite set of parameters under mild conditions, although the log likelihood function is not strictly concave. We then present an efficient algorithm for computing a local maximum of the likelihood function. Using our fast new algorithm, we present evidence from simulated current status data suggesting that the rate of convergence of the log-concave estimator is faster (between (n^{2/5}) and (n^{1/2})) than the unconstrained NPMLE (between (n^{1/3}) and (n^{1/2})).
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