Total testosterone levels are correlated to metabolic syndrome components |
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| Authors: | Rodrigo Blaya Leonardo Dalla Giacomassa Rocha Thomaz Fernanda Guilhermano Artur de Oliveira Paludo Luiza Rhoden Graziele Halmenschlager |
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| Institution: | 1. Post-Graduating Course of Medical Sciences, Universidade Federal De Ciências Da Saúde De Porto Alegre (UFCSPA), Urologist at Irmandade Santa Casa De Porto Alegre (ISCMPA) and Hospital Moinhos De Vento De Porto Alegre (HMV), Porto Alegre, RS, Brazil,;2. UFCSPA, Porto Alegre, RS, Brazil,;3. Universidade Católica De Pelotas (UCPel), Pelotas, RS, Brazil,;4. UFCSPA, Centro Universitário Ritter Dos Reis (UniRitter), Porto Alegre, RS, Brazil, and |
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| Abstract: | Introduction: Metabolic syndrome (MetS) is a constellation of interrelated risk factors of metabolic origin. Some studies suggest a possible link between low total testosterone (TT) levels and the presence of MetS.Aim: To analyze the strength and independence of associations between TT and MetS components in non-diabetic men.Methods: In this cross-sectional study, 143 non-diabetic men older than 40 were analyzed.Main outcomes measure: Blood samples were collected to evaluate metabolic profile and TT levels. MetS was defined as the presence of three or more of the following characteristics: fasting blood glucose levels?≥?100?mg/dL, triglyceride?≥?150?mg/dL, HDL-c??102?cm.Results: Mean age of the study population was 61.5?±?8.61 years old. MetS was present in 47.9% of the individuals. Thirty-four men had low TT and MetS was observed in 23 (70%) against 50 (46%) in those with normal TT (≥?300?ng/dL) (OR 4.94, p?p?=?0.03) and HDL-c (Beta: 0.19; p?=?0.04) remained significantly correlated with TT levels.Conclusions: Low TT levels were associated with MetS diagnosis. Abdominal obesity was the MetS component independently correlated to low TT levels. |
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| Keywords: | Testosterone hypogonadism metabolic syndrome X abdominal obesity waist circumference insulin resistance |
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