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Marginal homogeneity,symmetry, and independence
Authors:Nathan Mantel  David P. Byar
Affiliation:1. George Washington University , Bethesda, Maryland;2. Clinical and Diagnostic Trials Section , National Cancer Institute , Bethesda, Maryland
Abstract:A contingency table of the mc form provides a convenient summary of data when c individuals in a matched set9 each belonging to a different one of c classifications, are identified as belonging to one of m categories, A study in which matched sets (c=3) of 1 case, 1 hospital control, and 1 neighborhood control are classified into one of m=4 occupational categories would be an example, Independence in the cxm tables for each of the matched sets implies symmetry in the summary mc table with consequent marginal homogeneity. Adaptation of the Mantel-Haenszel procedure for testing independence to the case of many cxm tables so as to yield a chi square with (cl)(ml) degrees of freedom (DF) provides a test of marginal homogeneity in the summary mc table. This can be viewed as a test of symmetry directed against alternatives which would make for marginal inhomogeneity and can differ
Keywords:contingency tables  hypercubic contingency tables  Mantel-Haenszel procedure  multinomial distribution  Chi-square tests  loglineaz models  matched case-control studies  marginal homogeneity
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